3dhk H 1.73 BS03 23U H 1 Y60A W60D A190 C191 S195 V213 S214 W215 G216 E217 F227 Y47 W50 A192 C193 S197 V217 S218 W219 G220 E221 F231 3.4.21.5 0004252,0005509,0006508,0007596 Ki=47nM -logKd/Ki=7.33, Ki=47nM IC50=12nM P00734 19520086 1601 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 5mjt H 1.4 BS02 23U H 1 Y60A W60D N98 L99 I174 S190 V213 S214 W215 G216 E217 F227 Y47 W50 N95 L96 I172 S193 V218 S219 W220 G221 E222 F232 H57 D102 E192 G193 D194 S195 H43 D99 E195 G196 D197 S198 3.4.21.5 0004252,0005509,0006508,0007596 IC50=12nM P00734 301 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDSCEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF