4ly1 A 1.57 BS03 20Y A 1 Y29 M35 L144 H145 H146 G154 F155 C156 D181 H183 F210 L276 G305 G306 Y308 Y18 M24 L133 H134 H135 G143 F144 C145 D170 H172 F199 L265 G294 G295 Y297 3.5.1.-,3.5.1.98 0004407 Kd=0.0552uM -logKd/Ki=7.26, Kd=0.0552uM IC50=100nM, Ki=1.5nM, Kd=55.2nM Q92769 23897821 407 GKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 4ly1 B 1.57 BS03 20Y B 1 Y29 M35 L144 H145 H146 G154 F155 C156 D181 H183 F210 L276 G305 G306 Y308 Y17 M23 L132 H133 H134 G142 F143 C144 D169 H171 F198 L264 G293 G294 Y296 3.5.1.-,3.5.1.98 0004407 Kd=0.0552uM IC50=100nM, Ki=1.5nM, Kd=55.2nM Q92769 23897821 408 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLP 4ly1 C 1.57 BS03 20Y C 1 M35 L144 H145 H146 G154 F155 C156 D181 H183 F210 L276 G305 G306 Y308 M23 L132 H133 H134 G142 F143 C144 D169 H171 F198 L264 G293 G294 Y296 3.5.1.-,3.5.1.98 0004407 Kd=0.0552uM IC50=100nM, Ki=1.5nM, Kd=55.2nM Q92769 23897821 406 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRML