4l6q A 2.79 BS01 1WU A 1 I98 A119 K121 M169 E170 Y171 M172 N219 L221 D232 I72 A93 K95 M143 E144 Y145 M146 N193 L195 D206 D214 K216 N219 D232 T253 D188 K190 N193 D206 T227 2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=6.27, IC50=0.54uM O75116 24049062 501 QRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDVETFPIPKAFVGNQLPFIGFTYYR 4l6q B 2.79 BS01 1WU B 1 I98 V106 A119 K121 M169 E170 Y171 M172 N219 L221 D232 F384 I72 V80 A93 K95 M143 E144 Y145 M146 N193 L195 D206 F358 D214 K216 N219 D232 T253 D188 K190 N193 D206 T227 2.7.11.1 0004672,0004674,0005524,0006468 O75116 24049062 501 QRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDVETFPIPKAFVGNQLPFIGFTYYR