4l02 A 2.75 BS01 1V2 A 1 D81 F173 I174 V177 D178 F192 T196 L268 F288 F303 H311 G342 D77 F169 I170 V173 D174 F188 T192 L264 F284 F299 H307 G338 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 -logKd/Ki=7.70, IC50=0.02uM IC50=20nM Q9NYA1 23845219 401 AMGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 4l02 B 2.75 BS01 1V2 B 1 D81 F173 I174 V177 D178 F192 T196 L268 F288 F303 M306 H311 D74 F166 I167 V170 D171 F183 T187 L247 F267 F282 M285 H290 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 IC50=20nM Q9NYA1 23845219 401 SGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKKGVFAVDGELMVSEAVQGQVHPNYFWMVS 4l02 C 2.75 BS01 1V2 C 1 D81 F173 I174 V177 D178 F192 T196 L268 M272 F288 F303 M306 H311 L319 D76 F168 I169 V172 D173 F187 T191 L249 M253 F269 F284 M287 H292 L300 2.3.1.-,2.7.1.91 0000287,0001568,0001727,0003376,0003677,0005515,0005516,0005524,0005634,0005654,0005737,0005768,0005829,0005886,0005905,0006473,0006629,0006670,0006954,0007420,0008283,0008284,0008289,0008481,0010008,0010800,0010803,0016020,0016301,0016310,0016407,0017050,0019722,0030100,0030139,0030148,0030307,0030335,0031398,0031901,0032651,0032740,0034612,0035556,0035924,0038036,0043066,0043231,0045202,0045766,0045840,0045931,0045987,0046512,0046521,0048146,0050764,0051092,0051721,0070301,0071363,0071897,0090520,0098793,0150077,1900060,1900745,1901224,1903978,1905364 IC50=20nM Q9NYA1 23845219 401 MGSGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPNYFWMVSG