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BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1ohr:A (2.1) BS01 1UN ? GO:0004190 ... Q9Q288 9397180 MOAD: Ki=2nM
    PDBbind: -logKd/Ki=8.70, Ki=2nM
    2 1ohr:B (2.1) BS01 1UN ? GO:0004190 ... Q9Q288 9397180 PDBbind: -logKd/Ki=8.70, Ki=2nM
    3 2pym:A (1.9) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 MOAD: Kd=150nM
    PDBbind: -logKd/Ki=6.82, Kd=150nM
    4 2pym:B (1.9) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 PDBbind: -logKd/Ki=6.82, Kd=150nM
    5 2pyn:A (1.85) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 MOAD: Kd=27nM
    PDBbind: -logKd/Ki=7.57, Kd=27nM
    6 2pyn:B (1.85) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 PDBbind: -logKd/Ki=7.57, Kd=27nM
    7 2q63:A (2.2) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 MOAD: Kd=66nM
    PDBbind: -logKd/Ki=7.18, Kd=66nM
    8 2q63:B (2.2) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 PDBbind: -logKd/Ki=7.18, Kd=66nM
    9 2q64:A (2.5) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 PDBbind: -logKd/Ki=8.52, Kd=3.0nM
    10 2q64:B (2.5) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 17977555 MOAD: Kd=3nM
    PDBbind: -logKd/Ki=8.52, Kd=3.0nM
    11 2qak:A (2.2) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 N/A
    12 2qak:B (2.2) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03367 N/A
    13 2r5q:A (2.3) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... O12158 18092815 PDBbind: -logKd/Ki=8.57, Ki=2.7nM
    14 2r5q:B (2.3) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... O12158 18092815 MOAD: Ki=2.7nM
    PDBbind: -logKd/Ki=8.57, Ki=2.7nM
    15 2r5q:C (2.3) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... O12158 18092815
    16 2r5q:D (2.3) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... O12158 18092815 MOAD: Ki=2.7nM
    17 3ekx:A (1.97) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 PDBbind: -logKd/Ki=9.41, Kd=0.39nM
    18 3ekx:B (1.97) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 MOAD: Kd=0.39nM
    PDBbind: -logKd/Ki=9.41, Kd=0.39nM
    19 3el0:A (2.0) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 MOAD: Kd=34.1nM
    PDBbind: -logKd/Ki=7.47, Kd=34.1nM
    20 3el0:B (2.0) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 PDBbind: -logKd/Ki=7.47, Kd=34.1nM
    21 3el5:A (1.6) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 PDBbind: -logKd/Ki=7.72, Kd=18.9nM
    22 3el5:B (1.6) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P03369 22712830 MOAD: Kd=18.9nM
    PDBbind: -logKd/Ki=7.72, Kd=18.9nM
    23 7doz:A (1.91) BS01 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 34609269
    24 7doz:A (1.91) BS02 1UN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P04585 34609269
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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