2hnc A 1.55 BS02 1SA A 1 H94 H119 L198 T199 T200 H91 H116 L194 T195 T196 H64 H94 H96 E106 H119 T199 H61 H91 H93 E103 H116 T195 4.2.1.1,4.2.1.69 0002009,0004064,0004089,0005515,0005737,0005829,0005886,0006730,0008270,0015670,0016829,0018820,0032230,0032849,0038166,0043209,0044070,0045177,0046872,0046903,0051453,0070050,0070062,2001150,2001225 Ki=60nM -logKd/Ki=7.22, Ki=60nM Ki=60nM, IC50=2900nM P00918 17000110 265 HWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK 5tuo A 2.5 BS02 1SA A 1 H84 T86 H110 H112 L190 T191 A192 H61 T63 H87 H89 L167 T168 A169 H85 H110 H112 E116 H129 T191 H62 H87 H89 E93 H106 T168 4.2.1.1 0004089,0008270,0046872 Ki=323nM -logKd/Ki=6.49, Ki=323nM A0A0M3KL20 28002963 303 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo B 2.5 BS02 1SA B 1 H110 H112 L190 T191 H87 H89 L160 T161 H85 H110 H112 E116 H129 T191 H62 H87 H89 E93 H106 T161 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo C 2.5 BS02 1SA C 1 H84 H110 H112 L190 T191 A192 H63 H89 H91 L169 T170 A171 H85 H110 H112 E116 H129 T191 H64 H89 H91 E95 H108 T170 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo D 2.5 BS02 1SA D 1 H84 H110 L190 T191 A192 H59 H85 L163 T164 A165 H85 H110 H112 E116 H129 T191 H60 H85 H87 E91 H104 T164 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 WDYKNENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKKNSPNQRPVQPDYNTVIIKSSAETR 5tuo E 2.5 BS02 1SA E 1 H110 H129 L190 T191 H91 H110 L171 T172 H85 H110 H112 E116 H129 T191 H66 H91 H93 E97 H110 T172 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 NTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo F 2.5 BS02 1SA F 1 H110 H129 L190 T191 H83 H99 L151 T152 H85 H110 H112 E116 H129 T191 H58 H83 H85 E89 H99 T152 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 302 WDYENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKLSAHFVHKDAKGRLLVLAIGFENPNLDPILEGIQKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIVSAKQLAEIKKRMPNQRPVQPDYNTVIIKSSAET 5tuo G 2.5 BS02 1SA G 1 H110 H129 L190 T191 H88 H107 L168 T169 H85 H110 H112 E116 H129 T191 H63 H88 H90 E94 H107 T169 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 TKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNFKEVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR 5tuo H 2.5 BS02 1SA H 1 W23 H84 H110 H112 L190 T191 A192 W1 H60 H86 H88 L161 T162 A163 H85 H110 H112 E116 H129 T191 H61 H86 H88 E92 H105 T162 4.2.1.1 0004089,0008270,0046872 Ki=323nM A0A0M3KL20 28002963 303 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKVALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR