4kba A 1.98 BS01 1QM A 1 I23 A36 K38 M80 M82 L85 G86 L135 I148 I21 A34 K36 M78 M80 L83 G84 L133 I146 D128 K130 D126 K128 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=6nM -logKd/Ki=8.22, IC50=6.0nM IC50=6.0nM P48730 23919824 401 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLRISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 4kba B 1.98 BS01 1QM B 1 I15 I23 A36 K38 M80 M82 L85 G86 L135 I148 I13 I21 A34 K36 M72 M74 L77 G78 L127 I140 D128 K130 D120 K122 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=6nM IC50=6.0nM P48730 23919824 401 LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 4kba C 1.98 BS01 1QM C 1 I15 I23 A36 M80 M82 L85 G86 L135 I148 I9 I17 A30 M74 M76 L79 G80 L129 I142 D128 K130 D122 K124 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=6nM IC50=6.0nM P48730 23919824 401 NRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 4kba D 1.98 BS01 1QM D 1 I15 I23 A36 K38 M82 L85 G86 L135 I148 I13 I16 A29 K31 M70 L73 G74 L123 I136 D128 K130 D116 K118 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=6nM IC50=6.0nM P48730 23919824 401 LRVGNRYRLGRKIGDIYLGTDIAAGEEVAIKLECPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML