4k60 A 1.5 BS02 1P8 A 1 A190 F191 K192 G216 A226 A170 F171 K172 G192 A200 H57 D102 K192 G193 D194 S195 G196 H44 D88 K172 G173 D174 S175 G176 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 ic50=570uM -logKd/Ki=3.24, IC50=570uM IC50=570000nM P23946 23659209 703 IIGGTECKPHSRPYMAYLEIVTNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN 5akk A 1.9 BS01 1P8 A 1 M310 M339 Y343 N472 A476 M306 M335 Y339 N466 A470 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F263 H330 D331 W332 N355 N374 Y379 Y460 D490 H518 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 ic50=99.3uM -logKd/Ki=4.00, IC50=99.3uM P34913 25931264 1550 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 5akk A 1.9 BS02 1P8 A 2 P371 M469 N472 P367 M463 N466 F267 H334 D335 W336 N359 N378 Y383 Y466 D496 H524 F263 H330 D331 W332 N355 N374 Y379 Y460 D490 H518 3.1.3.76,3.3.2.10 0000287,0003824,0004301,0005737,0005777,0005782,0005829,0006629,0009056,0009636,0010628,0015643,0016311,0016787,0016791,0033885,0042577,0042632,0042803,0046272,0046839,0046872,0052642,0070062,0090181,0097176 ic50=99.3uM -logKd/Ki=4.00, IC50=99.3uM P34913 25931264 1551 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDAR 5rjo A 1.22 BS01 1P8 A 1 P1340 V1345 Y1350 Y1353 Y1395 P25 V30 Y35 Y38 Y80 ? Q8WWQ0 1501 YDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKR 7qxt AAA 1.51 BS01 1P8 AAA 1 T1023 V1024 K1026 T45 V46 K48 3.6.1.- Q6PL18 36367089 1203 SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQPMDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRACALRDTAYAIIKEELDEDFEQLCEEIQESR 7ze6 A 1.04 BS01 1P8 A 1 P82 N140 P43 N101 ? O60885 36367089 202 GSHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE