4jh0 A 2.35 BS01 1MD A 1 R125 E205 E206 Y547 S630 Y662 Y666 N710 R87 E167 E168 Y509 S592 Y624 Y628 N672 Y547 S630 Y631 D708 H740 Y509 S592 Y593 D670 H702 3.4.14.5 0001618,0001662,0001666,0002020,0004177,0004252,0005102,0005515,0005576,0005765,0005886,0005925,0006508,0007155,0008236,0008239,0008284,0009986,0010716,0016020,0016324,0016486,0019065,0030027,0030139,0031258,0031295,0033632,0035641,0036343,0042110,0042802,0042803,0042995,0043542,0045121,0045499,0046581,0046718,0046813,0050919,0061025,0070062,0070161,0090024,0120116 Ki=0.94nM -logKd/Ki=9.03, Ki=0.94nM P27487 23964740 801 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 4jh0 B 2.35 BS01 1MD B 1 R125 E205 E206 Y547 S630 Y662 Y666 N710 R87 E167 E168 Y509 S592 Y624 Y628 N672 Y547 S630 Y631 D708 H740 Y509 S592 Y593 D670 H702 3.4.14.5 0001618,0001662,0001666,0002020,0004177,0004252,0005102,0005515,0005576,0005765,0005886,0005925,0006508,0007155,0008236,0008239,0008284,0009986,0010716,0016020,0016324,0016486,0019065,0030027,0030139,0031258,0031295,0033632,0035641,0036343,0042110,0042802,0042803,0042995,0043542,0045121,0045499,0046581,0046718,0046813,0050919,0061025,0070062,0070161,0090024,0120116 Ki=0.94nM P27487 23964740 801 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP