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BioLiP
Download all results in tab-seperated text for 6 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4j1p:A (1.08) BS01 1K0 ? N/A P25440 24391744 MOAD: Kd=0.206uM
    PDBbind: -logKd/Ki=7.05, IC50=0.09uM
    BindingDB: Kd=5800nM, IC50=251nM
    2 4j3i:A (1.24) BS01 1K0 ? N/A O60885 24391744 MOAD: Kd=8.93uM
    PDBbind: -logKd/Ki=5.74, IC50=1.8uM
    BindingDB: IC50=510nM, Kd=1100nM
    3 4mr3:A (1.68) BS01 1K0 ? N/A O60885 24248379 PDBbind: -logKd/Ki=5.94, Kd=1142nM
    BindingDB: IC50=510nM, Kd=1100nM
    4 4mr4:A (1.66) BS01 1K0 ? N/A O60885 24248379 PDBbind: -logKd/Ki=5.94, Kd=1142nM
    BindingDB: IC50=510nM, Kd=1100nM
    5 4mr5:A (1.63) BS01 1K0 ? N/A P25440 24248379 PDBbind: -logKd/Ki=6.60, Kd=251nM
    BindingDB: Kd=5800nM, IC50=251nM
    6 4mr6:A (1.67) BS01 1K0 ? N/A P25440 24248379 PDBbind: -logKd/Ki=6.60, Kd=251nM
    BindingDB: Kd=5800nM, IC50=251nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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