4j52 A 2.3 BS01 1J3 A 1 L59 C67 A80 G81 K82 V114 L132 C133 R134 R136 F183 L22 C30 A43 G44 K45 V77 L95 C96 R97 R99 F146 D176 K178 G180 N181 D194 T214 D139 K141 G143 N144 D157 T177 2.7.11.21 0004672,0005524,0006468 ic50=3nM -logKd/Ki=8.52, IC50=3nM IC50=3.0nM P53350 23664874 400 KEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKVLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPS