4hy0 A 2.84 BS03 1AQ A 1 K297 G306 L307 T308 D309 K311 E314 Q319 W323 K44 G53 L54 T55 D56 K58 E61 Q66 W70 2.3.2.27 -logKd/Ki=6.70, IC50=200nM IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 A 2.84 BS04 1AQ F 1 T345 L348 T92 L95 2.3.2.27 -logKd/Ki=6.70, IC50=200nM IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 B 2.84 BS02 1AQ B 1 K297 K299 G306 L307 T308 D309 W310 E314 Q319 W323 K44 K46 G53 L54 T55 D56 W57 E61 Q66 W70 2.3.2.27 -logKd/Ki=6.70, IC50=200nM IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 B 2.84 BS03 1AQ E 1 T345 L348 T92 L95 2.3.2.27 -logKd/Ki=6.70, IC50=200nM IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 C 2.84 BS02 1AQ C 1 K297 G306 L307 T308 D309 K311 E314 Q319 W323 K44 G53 L54 T55 D56 K58 E61 Q66 W70 2.3.2.27 IC50=200nM P98170 23298277 402 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEE 4hy0 C 2.84 BS03 1AQ D 1 T345 H346 E349 T92 H93 E96 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEE 4hy0 C 2.84 BS04 1AQ H 1 L344 L348 L91 L95 2.3.2.27 IC50=200nM P98170 23298277 402 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEE 4hy0 D 2.84 BS01 1AQ A 1 T345 L348 E349 T92 L95 E96 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC 4hy0 D 2.84 BS04 1AQ D 1 G306 L307 T308 D309 E314 W323 G53 L54 T55 D56 E61 W70 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC 4hy0 E 2.84 BS03 1AQ E 1 K297 G306 L307 T308 D309 K311 E314 Q319 W323 K44 G53 L54 T55 D56 K58 E61 Q66 W70 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 F 2.84 BS02 1AQ F 1 K297 G306 L307 T308 D309 E314 Q319 W323 K44 G53 L54 T55 D56 E61 Q66 W70 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy0 G 2.84 BS01 1AQ B 1 T345 E349 T92 E96 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC 4hy0 G 2.84 BS03 1AQ G 1 K297 G306 L307 T308 D309 W310 E314 Q319 W323 K44 G53 L54 T55 D56 W57 E61 Q66 W70 2.3.2.27 IC50=200nM P98170 23298277 403 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC 4hy0 H 2.84 BS02 1AQ H 1 G306 L307 T308 D309 E314 Q319 Y324 G53 L54 T55 D56 E61 Q66 Y71 2.3.2.27 IC50=200nM P98170 23298277 402 TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLE 4hy5 A 1.752 BS02 1AQ A 1 D297 G306 L307 R308 C309 E311 D314 W323 D46 G55 L56 R57 C58 E60 D63 W72 2.3.2.27 ic50=1.3nM -logKd/Ki=8.89, IC50=1.3nM Q13490 23298277 402 GSSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRY 4hy5 B 1.752 BS02 1AQ B 1 G306 L307 R308 C309 W310 E311 D314 W323 G50 L51 R52 C53 W54 E55 D58 W67 2.3.2.27 ic50=1.3nM Q13490 23298277 402 NLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRY