4hyi A 1.399 BS01 1AO A 1 Y20 A36 K38 E85 Y86 C87 E91 E134 L137 D148 Y18 A34 K36 E80 Y81 C82 E86 E129 L132 D143 D130 K132 E134 N135 D148 T170 D125 K127 E129 N130 D143 T165 2.7.11.1 0000077,0004672,0004674,0005524,0006468 ic50=3nM -logKd/Ki=8.52, IC50=3nM EC50=750nM, IC50=2.0nM O14757 23535330 304 VPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAK