4hxz A 2.7 BS01 19Y A 1 I38 N41 S42 E45 D68 G72 M73 V115 T162 I164 I31 N34 S35 E38 D61 G65 M66 V98 T145 I147 5.6.2.2 0003677,0003918,0005524,0005694,0006265 -logKd/Ki=6.05, Ki=0.9uM A0A0J9WZF0 23352267 1401 SIEVLTGLDPVKKRPGMYTNIENPNHLIQEIIDNSVDEVLAGFASKINITLYEDNSIEVADDGRGMPVDIHPEHKMSGIELIMTKLHSGGKFSHGVGVSVVNALSTRLEAEIKRDGNVYHIVFEDGFKTKDLEIIDNVGKKNTGTKIRFWPNKKYFDDIKVNFKALKNLLEAKAILCKALTIKYSNEIKKEKLTWHFETGLKGYLDHKLEAETLPAEPFIIDNFSNGDSYLDAVFCWCEDPSESIKNSYVNLIPTPQDGTHVTGLKNGIYDAIKAYIEKNSLSVKNIKITANDSFAQLNYVISVKITNPQFAGQTKEKLSNKDVTNFVATAVKDLLTIWLNQNPDEARQIVENISKVAQKRINADL 4hxz B 2.7 BS01 19Y B 1 I38 N41 E45 D68 R71 G72 M73 P74 V115 T162 I164 I32 N35 E39 D62 R65 G66 M67 P68 V100 T147 I149 5.6.2.2 0003677,0003918,0005524,0005694,0006265 A0A0J9WZF0 23352267 1401 KSIEVLTGLDPVKKRPGMYTNIENPNHLIQEIIDNSVDEVLAGFASKINITLYEDNSIEVADDGRGMPVDIHPEHKMSGIELIMTKLHSGGKFSNHGVGVSVVNALSTRLEAEIKRDGNVYHIVFEDGFKTKDLEIIDNVGKKNTGTKIRFWPNKKYFDDIKVNFKALKNLLEAKAILCKALTIKYSNEIKKEKLTWHFETGLKGYLDHKETLPAEPFIIDNFSNGDSYLDAVFCWNSYVNLIPTPQDGTHVTGLKNAQLNYVISVKITNPTKEKLSNKDVTNF 4hz5 A 2.7 BS01 19Y A 1 I46 N49 E53 D76 R79 G80 M81 P82 H118 T169 I28 N31 E35 D58 R61 G62 M63 P64 H84 T135 5.6.2.2 0003677,0003918,0005524,0006265 -logKd/Ki=5.92, Ki=1.2uM H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE 4hz5 B 2.7 BS01 19Y B 1 I46 N49 E53 D76 R79 G80 M81 P82 T169 V171 I28 N31 E35 D58 R61 G62 M63 P64 T135 V137 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYE 4hz5 C 2.7 BS01 19Y C 1 I46 N49 E53 D76 R79 G80 M81 P82 T169 I28 N31 E35 D58 R61 G62 M63 P64 T135 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE 4hz5 D 2.7 BS01 19Y D 1 I46 N49 E53 D76 R79 G80 M81 I28 N31 E35 D58 R61 G62 M63 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHSGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE 4hz5 E 2.7 BS01 19Y E 1 I46 N49 E53 D76 R79 G80 M81 P82 T169 V171 I28 N31 E35 D58 R61 G62 M63 P64 T135 V137 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE 4hz5 F 2.7 BS01 19Y F 1 I46 N49 E53 D76 R79 G80 M81 P82 T169 I28 N31 E35 D58 R61 G62 M63 P64 T135 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE 4hz5 G 2.7 BS01 19Y G 1 N49 E53 D76 R79 G80 M81 P82 G119 T169 N31 E35 D58 R61 G62 M63 P64 G85 T135 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHHGVGASVVNALSKWLEVHIVRDGVEYMERFEDGGKPVGTLKKIGKTKKRNGTSVTFLPDDTIFSTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYE 4hz5 J 2.7 BS01 19Y J 1 N49 E53 D76 R79 G80 M81 P82 N31 E35 D58 R61 G62 M63 P64 5.6.2.2 0003677,0003918,0005524,0006265 H7C794 23352267 301 GLEAVRKRPGMYIGSTDSRGLHHLVYEIVDNAVDEALSGYGNEINVTIQKDNSICVADSGRGMPTGMHASGIPTVEVIFTVLHGVGASVVNALSKWLEVHIVRDGEYMERFEDGGKPVGTLKKIGTKNGTSVTFLPDDTIFTTNFSYEILAERLRESAFLLKGVKITLTDERGEEPKEEVFHYEE