4hw2 A 2.8 BS01 19H A 1 A227 F228 M231 M250 V253 F254 R263 L267 F270 I294 A55 F56 M59 M78 V81 F82 R91 L95 F98 I122 ? 0042981 -logKd/Ki=7.26, Ki=0.055uM Ki=55nM Q07820 23244564 401 GDELYRQSLEIISRYLREQATGAKDTKPMSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 4hw2 B 2.8 BS01 19H B 1 A227 F228 M250 V253 F254 R263 L267 F270 A57 F58 M80 V83 F84 R93 L97 F100 ? 0042981 Ki=55nM Q07820 23244564 401 GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 4hw2 C 2.8 BS01 19H C 1 A227 F228 M231 M250 V253 F254 R263 L267 F270 G271 A57 F58 M61 M80 V83 F84 R93 L97 F100 G101 ? 0042981 Ki=55nM Q07820 23244564 400 GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH 4hw2 D 2.8 BS01 19H D 1 F228 M231 V253 F254 R263 L267 F270 F58 M61 V83 F84 R93 L97 F100 ? 0042981 Ki=55nM Q07820 23244564 400 GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 4hw2 E 2.8 BS01 19H E 1 A227 L246 M250 V253 F254 R263 T266 L267 F270 A57 L76 M80 V83 F84 R93 T96 L97 F100 ? 0042981 Ki=55nM Q07820 23244564 400 GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV 4hw2 F 2.8 BS01 19H F 1 A227 F228 M231 M250 V253 F254 R263 T266 L267 F270 A57 F58 M61 M80 V83 F84 R93 T96 L97 F100 ? 0042981 Ki=55nM Q07820 23244564 400 GDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH 4wmu A 1.55 BS03 19H A 1 A227 F228 L246 M250 F254 R263 T266 L267 F270 G271 I294 A423 F424 L442 M446 F450 R459 T462 L463 F466 G467 I490 ? 0005515,0006974,0008643,0015144,0015768,0016020,0030288,0034219,0034289,0042597,0042956,0042981,0043190,0055052,0055085,0060326,1901982,1990060 Kd=0.18uM -logKd/Ki=6.74, Kd=0.18uM P0AEX9,Q07820 25909780 402 GKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTGSELYRQSLEIISRYLREQATGAADTAPMGASGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH