4hhy	A	2.3637	BS01	15R	A	1	L108 D109 H201 G202 R217 A219 Y228 G233 Y235 S243 Y246 E327	L108 D109 H201 G202 R217 A219 Y228 G233 Y235 S243 Y246 E327	S243 Y246 E327	S243 Y246 E327	2.4.2.-,2.4.2.30	0003950		ic50=1.92nM		IC50=1.9nM	P09874	23473053	401 	KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK
4hhy	B	2.3637	BS01	15R	B	1	D105 L108 D109 H201 G202 R217 I218 A219 Y228 G233 Y235 S243 Y246	D104 L107 D108 H192 G193 R208 I209 A210 Y219 G224 Y226 S234 Y237	S243 Y246 E327	S234 Y237 E318	2.4.2.-,2.4.2.30	0003950		ic50=1.92nM		IC50=1.9nM	P09874	23473053	401 	SKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK
4hhy	C	2.3637	BS01	15R	C	1	L108 D109 V112 H201 G202 R217 A219 Y235 F236 S243 Y246	L103 D104 V107 H196 G197 R212 A214 Y230 F231 S238 Y241	S243 Y246 E327	S238 Y241 E322	2.4.2.-,2.4.2.30	0003950		ic50=1.92nM	-logKd/Ki=8.72, IC50=1.92nM	IC50=1.9nM	P09874	23473053	401 	KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT
4hhy	D	2.3637	BS01	15R	D	1	L108 D109 H201 G202 R217 I218 A219 Y228 Y235 S243 Y246	L85 D86 H167 G168 R183 I184 A185 Y194 Y201 S209 Y212	S243 Y246 E327	S209 Y212 E293	2.4.2.-,2.4.2.30	0003950		ic50=1.92nM		IC50=1.9nM	P09874	23473053	401 	LPKPVQDLIKMIFDVKAMVEDLQGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDNNADSVQAKAEMLDNLLDIEVAYSLPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLK