2pj5 A 1.65 BS02 11B A 1 H69 E72 R127 N144 R145 H196 Y198 L203 S207 I247 Y248 D255 E270 H64 E67 R122 N139 R140 H192 Y194 L199 S203 I243 Y244 D251 E266 H69 E72 R127 H196 E270 H64 E67 R122 H192 E266 3.4.17.2 0004181,0006508,0008270 ic50=15nM -logKd/Ki=7.82, IC50=15nM P09955 18219114 401 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL 2pj5 B 1.65 BS02 11B B 1 H69 E72 R127 N144 R145 E163 T164 H196 Y198 L203 S207 Y248 D255 E270 H64 E67 R122 N139 R140 E158 T159 H192 Y194 L199 S203 Y244 D251 E266 H69 E72 R127 H196 E270 H64 E67 R122 H192 E266 3.4.17.2 0004181,0006508,0008270 ic50=15nM P09955 18219114 501 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL 2pj5 C 1.65 BS02 11B C 1 H69 E72 R127 N144 R145 H196 Y198 L203 S207 Y248 D255 E270 H65 E68 R123 N140 R141 H193 Y195 L200 S204 Y245 D252 E267 H69 E72 R127 H196 E270 H65 E68 R123 H193 E267 3.4.17.2 0004181,0006508,0008270 ic50=15nM P09955 18219114 601 TGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL