4gv1 A 1.49 BS01 0XZ A 1 K158 G162 V164 A177 K179 M227 Y229 A230 E234 E278 M281 D292 F438 K16 G20 V22 A35 K37 M85 Y87 A88 E92 E136 M139 D150 F296 D274 K276 N279 D292 T312 D132 K134 N137 D150 T170 2.7.11.1 0004672,0004674,0005524,0006468 ic50=3nM -logKd/Ki=8.52, IC50=3nM IC50=4.2nM P31749 23394218 501 SRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPSMECVDSERRPHFPQFDYSAS