3ujs B 1.65 BS02 0V5 B 1 G37 A38 S39 Q165 E166 D244 D317 K342 R371 S372 K393 G37 A38 S39 Q165 E166 D244 D317 K342 R371 S372 K393 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 S39 H157 E166 E209 D244 E292 D317 K342 H370 K393 4.2.1.11 0000015,0000287,0001917,0004634,0005515,0005615,0005737,0005829,0005886,0006094,0006096,0016020,0016829,0043025,0043204,0046872,0061621,0070062 Ki=0.4mM P09104 22437160 602 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL 4umb A 2.17 BS02 0V5 A 1 R94 K99 A166 R167 K188 R236 H270 R79 K84 A151 R152 K173 R221 H255 2.5.1.54 0003849,0005737,0008652,0009058,0009073,0009423,0016740,0046872 Ki=99uM -logKd/Ki=4.00, Ki=99uM Q9K169 25245459 1353 KELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARA 4umb B 2.17 BS02 0V5 B 1 R94 K99 P100 G165 A166 R167 K188 R236 H270 R78 K83 P84 G149 A150 R151 K172 R220 H254 2.5.1.54 0003849,0005737,0008652,0009058,0009073,0009423,0016740,0046872 Ki=99uM -logKd/Ki=4.00, Ki=99uM Q9K169 25245459 1351 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb C 2.17 BS02 0V5 C 1 R94 K99 P100 R167 K188 R236 H270 R78 K83 P84 R151 K172 R220 H254 2.5.1.54 0003849,0005737,0008652,0009058,0009073,0009423,0016740,0046872 Ki=99uM Q9K169 25245459 1351 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 4umb D 2.17 BS02 0V5 D 1 R94 K99 P100 G165 A166 K188 R236 H270 R78 K83 P84 G149 A150 K172 R220 H254 2.5.1.54 0003849,0005737,0008652,0009058,0009073,0009423,0016740,0046872 Ki=99uM Q9K169 25245459 1351 ELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMAR 5u4h A 1.05 BS01 0V5 A 1 M91 R92 C116 R398 M93 R94 C118 R400 K22 N23 D49 R92 C116 R121 D306 H335 L371 R372 R398 K24 N25 D51 R94 C118 R123 D308 H337 L373 R374 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 A0A0R0VXX6 509 NAMDKFLITGGVKLEGEVRISGAKNAALPLLAAMILADSPITLTNVPNLKDVNTLVKLIGGLGVTISYENDTVKADTSTLDNQFAPYELVKTMRASILVLGPLLARYGNAKVSLPGGCAIGSRPVDQHLKALEALGAHIEVENGYVHATVDGRLKGGEVVFDMVTVGGTENILMAAALADGVTTIRNAAREPEITDLAQMLIKMGAKIEGLDTDTLVVTGVESLHGCEYAVVADRIETGSYLAAAAITGGRVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELDMLGKRPKAVSFRTLPHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELSRMGANIQVEGHDAVVTGVEKLQAAPVMATDLRASFSLVLAALVAEGDTLIDRIYHIDRGYEHVEEKLQGLGAKIKRVS 5u4h B 1.05 BS01 0V5 B 1 R92 C116 R398 R94 C118 R400 K22 N23 D49 R92 C116 R121 D306 H335 L371 R372 R398 K24 N25 D51 R94 C118 R123 D308 H337 L373 R374 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 A0A0R0VXX6 506 NAMDKFLITGGVKLEGEVRISGAKNAALPLLAAMILADSPITLTNVPNLKDVNTLVKLIGGLGVTISYENDTVKADTSTLDNQFAPYELVKTMRASILVLGPLLARYGNAKVSLPGGCAIGSRPVDQHLKALEALGAHIEVENGYVHATVDGRLKGGEVVFDMVTVGGTENILMAAALADGVTTIRNAAREPEITDLAQMLIKMGAKIEGLDTDTLVVTGVESLHGCEYAVVADRIETGSYLAAAAITGGRVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELDMLGKRPKAVSFRTLPHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELSRMGANIQVEGHDAVVTGVEKLQAAPVMATDLRASFSLVLAALVAEGDTLIDRIYHIDRGYEHVEEKLQGLGAKIKRVS 5wi5 A 2.0 BS01 0V5 A 1 M95 R96 C120 T121 R401 M95 R96 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIEA 5wi5 B 2.0 BS01 0V5 B 1 M95 R96 C120 T121 R401 M95 R96 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIEA 5wi5 C 2.0 BS01 0V5 C 1 R96 C120 T121 R401 R96 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIE 5wi5 D 2.0 BS01 0V5 D 1 C120 T121 R401 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIEA 6cn1 A 2.75 BS02 0V5 A 1 R93 C117 R400 R94 C118 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 502 AMDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 B 2.75 BS02 0V5 B 1 R93 C117 R400 R93 C117 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 501 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 C 2.75 BS02 0V5 C 1 R93 C117 R400 R93 C117 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 502 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 D 2.75 BS02 0V5 D 1 M92 R93 C117 A118 R400 M92 R93 C117 A118 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 501 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 E 2.75 BS02 0V5 E 1 R93 C117 R400 R93 C117 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 501 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 F 2.75 BS02 0V5 F 1 R93 C117 R400 R93 C117 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 502 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 G 2.75 BS02 0V5 G 1 M92 R93 C117 R400 M92 R93 C117 R400 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 501 MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6cn1 H 2.75 BS02 0V5 H 1 R93 C117 A118 R400 R94 C118 A119 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q88P88 502 AMDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNIQGAGTDTITIDGVERLDSANYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADINTGEDWIELDMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGVKALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG 6nkj A 1.3 BS01 0V5 A 1 R96 C120 T121 R401 R96 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIE 6nkj B 1.3 BS01 0V5 B 1 R96 C120 T121 R401 R96 C120 T121 R401 K23 N24 C120 R125 D309 R401 K23 N24 C120 R125 D309 R401 2.5.1.7 0003824,0005737,0008360,0008760,0009252,0016740,0016765,0019277,0051301,0071555 Q97NQ4 501 MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIE