4fc0 A 2.95 BS01 0T2 A 1 A480 K482 E500 V503 L504 L513 I526 T528 W530 C531 G533 G592 D593 F594 A34 K36 E54 V57 L58 L67 I80 T82 W84 C85 G87 G146 D147 F148 D575 K577 N579 N580 D593 S615 D129 K131 N133 N134 D147 S151 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.16, IC50=69nM IC50=69nM P15056 22883026 901 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGGSILWMAPEVIRMNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP 4fc0 B 2.95 BS01 0T2 B 1 A480 K482 E500 L504 I526 T528 W530 C531 G533 H573 G592 D593 F594 A597 A34 K36 E54 L58 I80 T82 W84 C85 G87 H127 G146 D147 F148 A151 D575 K577 N579 N580 D593 W603 S615 D129 K131 N133 N134 D147 W157 S159 2.7.11.1 0004672,0005524,0006468 IC50=69nM P15056 22883026 901 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS