4f65 A 2.26 BS01 0S9 A 1 L484 E486 V492 A512 K514 E531 V561 Y563 A564 S565 G567 L630 L21 E23 V29 A47 K49 E66 V96 Y98 A99 S100 G102 L154 D623 A625 R627 N628 D641 D147 A149 R151 N152 D165 2.7.10.1 0004672,0004713,0005007,0005524,0006468 ic50=2.5nM -logKd/Ki=8.60, IC50=2.5nM IC50=63.1nM P11362 22612866 808 ELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQE 4f65 B 2.26 BS01 0S9 B 1 L484 A512 K514 V561 Y563 A564 S565 G567 L630 L25 A50 K52 V99 Y101 A102 S103 G105 L153 D623 A625 R627 N628 D641 D146 A148 R150 N151 D164 2.7.10.1 0004672,0004713,0005007,0005524,0006468 ic50=2.5nM IC50=63.1nM P11362 22612866 808 VSEYELPEDPRWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSN