4e5w A 1.86 BS01 0NT A 1 L881 G882 E883 V889 A906 M956 F958 L959 R1007 N1008 L1010 D1021 L29 G30 E31 V37 A54 M96 F98 L99 R147 N148 L150 D161 D1003 A1005 R1007 N1008 D1021 D1040 D143 A145 R147 N148 D161 D180 2.7.10.2 0004672,0004713,0005524,0006468 Ki=22nM -logKd/Ki=7.66, Ki=22nM Ki=22nM, EC50=>8800nM P23458 22591402 1201 GDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKNHIADLKKEIEILRNLYHENIVKYKGICTENGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK 4e5w B 1.86 BS01 0NT B 1 L881 G882 E883 V889 A906 M956 F958 L959 R1007 N1008 L1010 D1021 L17 G18 E19 V25 A42 M85 F87 L88 R136 N137 L139 D150 D1003 A1005 R1007 N1008 D1021 D1040 D132 A134 R136 N137 D150 D167 2.7.10.2 0004672,0004713,0005524,0006468 Ki=22nM Ki=22nM, EC50=>8800nM P23458 22591402 1202 VDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPNHIADLKKEIEILRNLYHENIVKYKGICTENGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIEKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALL