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BioLiP
Download all results in tab-seperated text for 28 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3ik3:A (1.9) BS01 0LI 2.7.10.2 GO:0004672 ... P00520 19878872 MOAD: ic50=2nM
    PDBbind: -logKd/Ki=8.70, IC50=2.0nM
    2 3ik3:B (1.9) BS01 0LI 2.7.10.2 GO:0004672 ... P00520 19878872 MOAD: ic50=2nM
    3 3oxz:A (2.2) BS01 0LI 2.7.10.2 GO:0004672 ... P00520 21118377 MOAD: ic50=8.6nM
    PDBbind: -logKd/Ki=8.07, IC50=8.6nM
    4 3zos:A (1.92) BS01 0LI 2.7.10.1 GO:0004672 ... Q08345 24768818 PDBbind: -logKd/Ki=8.89, Kd=1.3nM
    5 3zos:A (1.92) BS02 0LI 2.7.10.1 GO:0004672 ... Q08345 24768818 PDBbind: -logKd/Ki=8.89, Kd=1.3nM
    6 3zos:B (1.92) BS01 0LI 2.7.10.1 GO:0004672 ... Q08345 24768818
    7 3zos:B (1.92) BS02 0LI 2.7.10.1 GO:0004672 ... Q08345 24768818
    8 4c8b:A (2.75) BS01 0LI 2.7.10.2
    2.7.11.1    		 GO:0004672 ... O43353 26320862 BindingDB: IC50=1.000000nM
    9 4c8b:B (2.75) BS01 0LI 2.7.10.2
    2.7.11.1    		 GO:0004672 ... O43353 26320862 BindingDB: IC50=1.000000nM
    10 4qrc:A (1.901) BS01 0LI 2.7.10.1 GO:0004672 ... P22455 25317566 PDBbind: -logKd/Ki=6.34, IC50=452nM
    BindingDB: IC50=8.0nM
    11 4tyj:A (2.45) BS01 0LI 2.7.10.1 GO:0004672 ... P22455 25219510 BindingDB: IC50=8.0nM
    12 4u0i:A (2.0) BS01 0LI 2.7.10.1 GO:0004672 ... P10721 25239608 MOAD: ic50<11nM
    PDBbind: -logKd/Ki=8.22, IC50=6nM
    BindingDB: IC50=1.7nM
    13 4uxq:A (1.85) BS01 0LI 2.7.10.1 GO:0004672 ... P22455 25465127 MOAD: Kd=16nM
    PDBbind: -logKd/Ki=7.80, Kd=16.0nM
    BindingDB: IC50=8.0nM
    14 4v01:A (2.33) BS01 0LI 2.7.10.1 GO:0004672 ... P11362 25465127 PDBbind: -logKd/Ki=8.11, Kd=7.7nM
    15 4v01:B (2.33) BS01 0LI 2.7.10.1 GO:0004672 ... P11362 25465127
    16 4v04:A (2.12) BS01 0LI N/A GO:0004672 ... N/A 25465127 MOAD: Kd=7.7nM
    PDBbind: -logKd/Ki=8.11, Kd=7.7nM
    17 4v04:B (2.12) BS01 0LI N/A GO:0004672 ... N/A 25465127 MOAD: Kd=7.7nM
    18 6eg9:A (2.414) BS01 0LI 2.7.11.1 GO:0000287 ... Q9NWZ3 30679311 MOAD: ic50=66.9nM
    19 6eg9:B (2.414) BS01 0LI 2.7.11.1 GO:0000287 ... Q9NWZ3 30679311 MOAD: ic50=66.9nM
    20 6p3d:A (2.11) BS01 0LI 2.7.11.1 GO:0004672 ... P15056 32873792 MOAD: ic50=14nM
    21 6tu9:A (1.94) BS01 0LI ? GO:0004672 ... Q01973 32619402
    22 6tu9:B (1.94) BS01 0LI ? GO:0004672 ... Q01973 32619402
    23 7ote:A (2.49) BS01 0LI 2.7.10.2 GO:0004672 ... P12931 37848415
    24 7ote:B (2.49) BS01 0LI 2.7.10.2 GO:0004672 ... P12931 37848415
    25 7wf5:A (1.798) BS01 0LI 2.7.10.2 GO:0004672 ... P00523 35151199
    26 7wf5:B (1.798) BS01 0LI 2.7.10.2 GO:0004672 ... P00523 35151199
    27 8u8a:B (3.4) BS01 0LI 2.7.11.1
    3.6.5.-    		 GO:0000139 ... Q5S007 38263358
    28 8u8a:C (3.4) BS01 0LI 2.7.11.1
    3.6.5.-    		 GO:0000139 ... Q5S007 38263358
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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