3v7t A 2.09 BS01 0GX A 1 Q102 D203 S204 C205 Q206 S209 V227 W229 G230 G232 Q87 D188 S189 C190 Q191 S194 V212 W214 G215 G217 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM -logKd/Ki=7.21, Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t A 2.09 BS03 0GX C 1 P63 Y99 P48 Y84 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM -logKd/Ki=7.21, Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t B 2.09 BS01 0GX B 1 Q102 D203 S204 C205 Q206 S209 V227 W229 G230 G232 C233 Q87 D188 S189 C190 Q191 S194 V212 W214 G215 G217 C218 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t B 2.09 BS03 0GX D 1 P63 Y99 P48 Y84 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t C 2.09 BS01 0GX A 1 P63 Y99 P48 Y84 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM -logKd/Ki=7.21, Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t C 2.09 BS02 0GX C 1 Q102 D203 S204 C205 Q206 S209 V227 W229 G230 G232 Q87 D188 S189 C190 Q191 S194 V212 W214 G215 G217 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM -logKd/Ki=7.21, Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t D 2.09 BS01 0GX B 1 P63 Y99 P48 Y84 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 3v7t D 2.09 BS02 0GX D 1 Q102 D203 S204 C205 S209 V227 W229 G230 E231 G232 Q87 D188 S189 C190 S194 V212 W214 G215 E216 G217 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=62nM P20231 22264487 301 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP