1jq7 A 3.0 BS01 0FP A 1 N1062 H1063 S1132 L1133 S1134 S1135 R1165 R1166 N46 H47 S116 L117 S118 S119 R131 R132 3.4.21.97 0004252,0006508 P16753 11524687 261 QSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWDPFRSDSYGLLGNYVDALYIRERLPKLRYDKQLVGVTERESYVKA 1jq7 B 3.0 BS01 0FP B 1 E1331 H1363 S1432 L1433 S1434 S1435 K1456 G1464 R1465 I1531 E25 H45 S114 L115 S116 S117 K126 G134 R135 I192 H1363 S1432 S1434 H1457 R1465 R1466 H45 S114 S116 H127 R135 R136 3.4.21.97 0004252,0006508 P16753 11524687 561 QSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNYVDALYIRERLPKLRYDKQLVGVTERESYVKA 1nju A 2.7 BS01 0FP A 1 E31 N62 H63 S132 L133 S134 S135 R136 R137 C161 V163 G164 R165 I231 E28 N53 H54 S123 L124 S125 S126 R127 R128 C144 V146 G147 R148 I205 3.4.21.97 0004252,0006508 -logKd/Ki=7.30, IC50<0.05uM P16753 12549906 260 DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA 1nju B 2.7 BS01 0FP B 1 N362 H363 S432 L433 S434 S435 R436 R437 K456 C461 V463 G464 R465 N52 H53 S122 L123 S124 S125 R126 R127 K138 C143 V145 G146 R147 3.4.21.97 0004252,0006508 -logKd/Ki=7.30, IC50<0.05uM P16753 12549906 560 DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQASGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA 1nju C 2.7 BS01 0FP C 1 N1062 H1063 S1132 L1133 S1134 S1135 R1136 R1137 K1156 C1161 V1163 G1164 R1165 I1231 N53 H54 S123 L124 S125 S126 R127 R128 K136 C141 V143 G144 R145 I202 3.4.21.97 0004252,0006508 P16753 12549906 1260 DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA 1nju D 2.7 BS01 0FP D 1 E1331 H1363 S1432 L1433 S1434 S1435 R1436 R1437 C1461 V1463 G1464 R1465 R1466 I1531 E28 H54 S123 L124 S125 S126 R127 R128 C144 V146 G147 R148 R149 I205 H1363 S1432 S1434 H1457 R1465 R1466 H54 S123 S125 H140 R148 R149 3.4.21.97 0004252,0006508 P16753 12549906 1560 DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQLSVALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRCDDVEQTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQSGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA 1nkm A 2.7 BS01 0FP A 1 N62 H63 S132 S134 S135 R136 K156 C161 G164 R165 I231 N50 H51 S120 S122 S123 R124 K130 C135 G138 R139 I195 3.4.21.97 0004252,0006508 -logKd/Ki=7.30, IC50<0.05uM P16753 12549906 260 DEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQALPLNINHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKVVEFLSGSYAGLSLSSRRTTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFPDLTAADRDGLRAQWQGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQLVGVTERESYVKA