3uxd A 1.8 BS01 0CU A 1 W110 G131 I133 V159 E231 W109 G130 I132 V158 E230 0004425 -logKd/Ki=4.41, Ki=39.3uM 22685214 291 PRYLKGALKDVVQLSLRRPSLRASRQRPIISLRERILEFNKRNITAIIAVYKRKSPSGLDVERDPIEYAKFMERYAVGLVILTEEKYFNGSYEDLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSYGMEPAIVINDEEDLDIALRIGARIIIISSRDLETLEINKENQRKLISMIPSNVVKVAASGISERNEIEELRKLGVNAFEIGSSLMRNPEKIKELIL 3uxd B 1.8 BS01 0CU B 1 W110 G131 V159 E231 W109 G130 V158 E230 0004425 22685214 291 PRYLKGALKDVVQLSLRRPSLRASRQRPIISLRERILEFNKRNITAIIAVYKRKSPSGLDVERDPIEYAKFMERYAVGLVILTEEKYFNGSYEDLRKIASSVSIPILMWDFIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSYGMEPAIVINDEEDLDIALRIGARIIIISSRDLETLEINKENQRKLISMIPSNVVKVAASGISERNEIEELRKLGVNAFEIGSSLMRNPEKIKELIL 3uz5 A 1.9 BS01 0CU A 1 W110 G131 I133 V159 E231 W109 G130 I132 V158 E230 0004425 -logKd/Ki=7.22, Ki=0.06uM 22685214 291 PRYLKGWLEDVVQRSQRRPSVRASRQRPIISLKERILEFNKRNITAIMAVYKRKSPSGLDVERDPIEYAKFMERGVVGLAILTEEKYFNGSYEDLRKIASSVSVPILMWDIIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSLGMEPAIVIHDENDLDIALRIGARFIIITSHDLETLEINNENQRKLISMIPSNVVKVVASGISERNEIEELYKLGVNAFEIGTSLMRNPEKIKEFIQ 3uz5 B 1.9 BS01 0CU B 1 W110 D111 G131 I133 V159 E231 W109 D110 G130 I132 V158 E230 0004425 22685214 291 PRYLKGWLEDVVQRSQRRPSVRASRQRPIISLKERILEFNKRNITAIMAVYKRKSPSGLDVERDPIEYAKFMERGVVGLAILTEEKYFNGSYEDLRKIASSVSVPILMWDIIVKESQIDDAYNLGADTVGLIVKILTERELESLLEYARSLGMEPAIVIHDENDLDIALRIGARFIIITSHDLETLEINNENQRKLISMIPSNVVKVVASGISERNEIEELYKLGVNAFEIGTSLMRNPEKIKEFIQ