3up2 A 2.3001 BS01 0C8 A 1 R137 L139 G140 V147 A213 G216 R220 L263 A273 R14 L16 G17 V24 A90 G93 R97 L140 A150 D256 K258 E260 N261 D274 T292 D133 K135 E137 N138 D151 T169 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 Kd=40nM -logKd/Ki=7.40, Kd=40nM IC50=28nM, Kd=40nM O14965 22248356 1 KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK