3uol A 2.4 BS01 0C7 A 1 L139 L194 A213 G216 T217 L263 V279 L13 L68 A87 G90 T91 L137 V153 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 ic50=3.1nM -logKd/Ki=8.51, IC50=3.1nM IC50=3.1nM, Kd=18nM O14965 22248356 2 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 3uol B 2.4 BS01 0C7 B 1 L139 L194 A213 G216 T217 L263 V279 L13 L68 A87 G90 T91 L137 V153 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 ic50=3.1nM IC50=3.1nM, Kd=18nM O14965 22248356 1 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK