3unz A 2.8 BS01 0BZ A 1 L139 G140 A160 L194 Y212 A213 G216 R220 L263 V279 L13 G14 A34 L68 Y86 A87 G90 R94 L137 V153 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=7.80, Kd=16nM IC50=3.7nM, Kd=16nM O14965 22248356 2 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK 3unz B 2.8 BS01 0BZ B 1 R137 L139 V147 A160 L194 Y212 A213 G216 R220 L263 V279 R11 L13 V21 A34 L68 Y86 A87 G90 R94 L137 V153 D256 K258 E260 N261 D274 T292 D130 K132 E134 N135 D148 T166 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 IC50=3.7nM, Kd=16nM O14965 22248356 1 QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSK