3u8n A 2.35 BS01 09S A 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y182 Y189 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=10.17, Ki=0.067nM Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n A 2.35 BS02 09S E 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=10.17, Ki=0.067nM Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n B 2.35 BS01 09S A 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=10.17, Ki=0.067nM Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n B 2.35 BS02 09S B 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y183 Y190 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 -logKd/Ki=10.17, Ki=0.067nM Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n C 2.35 BS01 09S B 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n C 2.35 BS02 09S C 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y185 Y192 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n D 2.35 BS01 09S C 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n D 2.35 BS02 09S D 1 Y89 W143 T144 C188 Y192 Y89 W143 T144 C188 Y192 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n E 2.35 BS01 09S D 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n E 2.35 BS02 09S E 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n F 2.35 BS01 09S F 1 Y89 W143 T144 Y185 C188 Y192 Y89 W143 T144 Y182 C185 Y189 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n F 2.35 BS02 09S J 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n G 2.35 BS01 09S F 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n G 2.35 BS02 09S G 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n H 2.35 BS01 09S G 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n H 2.35 BS02 09S H 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n I 2.35 BS01 09S H 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n I 2.35 BS02 09S I 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n J 2.35 BS01 09S I 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n J 2.35 BS02 09S J 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n K 2.35 BS01 09S K 1 Y89 W143 T144 Y185 C188 Y192 Y89 W143 T144 Y182 C185 Y189 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n K 2.35 BS02 09S O 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n L 2.35 BS01 09S K 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n L 2.35 BS02 09S L 1 Y89 W143 T144 Y185 C188 Y192 Y89 W143 T144 Y181 C184 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n M 2.35 BS01 09S L 1 W53 A103 R104 L112 M114 W53 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGR 3u8n M 2.35 BS02 09S M 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGR 3u8n N 2.35 BS01 09S M 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n N 2.35 BS02 09S N 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y178 Y185 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n O 2.35 BS01 09S N 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n O 2.35 BS02 09S O 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n P 2.35 BS01 09S P 1 Y89 W143 T144 Y185 C188 Y192 Y89 W143 T144 Y181 C184 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n P 2.35 BS02 09S T 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n Q 2.35 BS01 09S P 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGR 3u8n Q 2.35 BS02 09S Q 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y182 Y189 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGR 3u8n R 2.35 BS01 09S Q 1 A103 R104 L112 M114 A103 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n R 2.35 BS02 09S R 1 Y89 W143 T144 Y192 Y89 W143 T144 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK 3u8n S 2.35 BS01 09S R 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n S 2.35 BS02 09S S 1 Y89 W143 T144 Y185 Y192 Y89 W143 T144 Y181 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRS 3u8n T 2.35 BS01 09S S 1 R104 L112 M114 R104 L112 M114 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG 3u8n T 2.35 BS02 09S T 1 Y89 W143 T144 C188 Y192 Y89 W143 T144 C184 Y188 ? 0004888,0005216,0005230,0005231,0005576,0006811,0007165,0007268,0016020,0034220,0042391,0043005,0043083,0045202,0050877,0060078,0060079,0098794,1904315 Ki=0.067nM P58154 22170047 211 LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG