3ro9 A 2.596 BS02 06U A 1 I9 V10 A11 L25 E32 M33 F36 S61 I62 L69 I121 I7 V8 A9 L23 E30 M31 F34 S59 I60 L67 I119 L25 W27 E32 M33 F36 L69 I118 T140 L23 W25 E30 M31 F34 L67 I116 T138 1.5.1.3 0000166,0004146,0005575,0005739,0006730,0016491,0046452,0046654,0046655,0050661 Q6FPH0 23375226 1 KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH 3ro9 B 2.596 BS02 06U B 1 V10 A11 E32 M33 F36 S61 I62 L69 I121 V8 A9 E30 M31 F34 S59 I60 L67 I119 L25 W27 E32 M33 F36 L69 I118 T140 L23 W25 E30 M31 F34 L67 I116 T138 1.5.1.3 0000166,0004146,0005575,0005739,0006730,0016491,0046452,0046654,0046655,0050661 Q6FPH0 23375226 1 KVPVVGIVAALLPEMGIGFQGNLPWRLAKEMKYFREVTTLTNDNSKQNVVIMGRKTWESIPQKFRPLPKRINVVVSRSFDGELRKVEDGIYHSNSLRNCLTALQSSLANENKIERIYIIGGGEIYRQSMDLADHWLITKIMPLPETTIPQMDTFLQKQELEQRFYDNSDKLVDFLPSSIQLEGRLTSQEWNGELVKGLPVQEKGYQFYFTLYTKKLEHHHHHHHH 4h95 A 2.6 BS02 06U A 1 I9 V10 M25 E32 F36 I112 I6 V7 M22 E29 F33 I109 M25 W27 E32 I33 F36 L69 V109 T133 M22 W24 E29 I30 F33 L66 V106 T130 1.5.1.3 0004146,0005739,0006730,0016491,0046452,0046654,0046655,0050661 IC50=60nM P22906 23375226 202 PNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK 4h95 B 2.6 BS02 06U B 1 I9 V10 E32 F36 I62 L69 I112 I6 V7 E29 F33 I59 L66 I109 M25 W27 E32 I33 F36 L69 V109 T133 M22 W24 E29 I30 F33 L66 V106 T130 1.5.1.3 0004146,0005739,0006730,0016491,0046452,0046654,0046655,0050661 IC50=60nM P22906 23375226 202 PNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK 4kak A 1.8 BS02 06U A 1 I7 V8 A9 E30 F31 F34 S59 N64 L67 I7 V8 A9 E30 F31 F34 S59 N64 L67 L22 E30 L22 E30 1.5.1.3 0000900,0003723,0003729,0004146,0005542,0005737,0005739,0005829,0006729,0006730,0008144,0016491,0017148,0031103,0031427,0046452,0046653,0046654,0046655,0050661,0051000,0070402,1990825,2000121 ic50=1300nM IC50=1300nM P00374 24053334 202 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 4kak B 1.8 BS02 06U B 1 I7 V8 E30 F31 F34 S59 P61 N64 I7 V8 E30 F31 F34 S59 P61 N64 L22 E30 L22 E30 1.5.1.3 0000900,0003723,0003729,0004146,0005542,0005737,0005739,0005829,0006729,0006730,0008144,0016491,0017148,0031103,0031427,0046452,0046653,0046654,0046655,0050661,0051000,0070402,1990825,2000121 ic50=1300nM IC50=1300nM P00374 24053334 202 VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND 4osg A 2.7 BS02 06U A 1 I5 A6 M20 D27 F31 M42 T46 I50 L54 I94 I5 A6 M20 D27 F31 M42 T46 I50 L54 I94 0004146,0046654,0050661 25288083 402 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR 4osg A 2.7 BS03 06U C 1 A145 Q146 A145 Q146 0004146,0046654,0050661 25288083 402 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR 4osg B 2.7 BS02 06U B 1 I5 M20 D27 L28 F31 M42 I50 L54 I94 I5 M20 D27 L28 F31 M42 I50 L54 I94 0004146,0046654,0050661 25288083 402 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR 4osg C 2.7 BS02 06U C 1 I5 A6 M20 D27 F31 I50 I94 I5 A6 M20 D27 F31 I50 I94 0004146,0046654,0050661 25288083 402 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR 4osg D 2.7 BS02 06U D 1 I5 A6 M20 D27 L28 F31 T46 I50 L54 I94 I5 A6 M20 D27 L28 F31 T46 I50 L54 I94 0004146,0046654,0050661 25288083 402 MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR 4xe6 X 2.692 BS01 06U X 1 L5 V6 A7 D27 L28 V31 I50 F92 L5 V6 A7 D27 L28 V31 I50 F92 L5 L5 1.5.1.3 0004146,0005829,0006730,0016491,0046452,0046654,0046655,0050661 IC50=19nM, Ki=2.8nM P0A017 201 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 4xec X 2.692 BS01 06U X 1 L5 V6 A7 D27 L28 V31 I50 F92 L5 V6 A7 D27 L28 V31 I50 F92 L5 L5 1.5.1.3 0004146,0005829,0006730,0016491,0046452,0046654,0046655,0050661 IC50=19nM, Ki=2.8nM P0A017 26098608 201 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 7t7q X 2.2 BS02 06U X 1 L5 V6 A7 Q19 D27 L28 V31 I50 F92 L5 V6 A7 Q19 D27 L28 V31 I50 F92 1.5.1.3 0004146,0005829,0006730,0016491,0046452,0046654,0046655,0050661 P0A017 35143481 202 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK 7t7s X 2.2 BS02 06U X 1 L5 V6 A7 Q19 D27 L28 V31 I50 F92 L5 V6 A7 Q19 D27 L28 V31 I50 F92 1.5.1.3 0004146,0005829,0006730,0016491,0046452,0046654,0046655,0050661 P0A017 35143481 202 TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK