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BioLiP
Download all results in tab-seperated text for 15 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3ro9:A (2.596) BS02 06U 1.5.1.3 GO:0000166 ... Q6FPH0 23375226
    2 3ro9:B (2.596) BS02 06U 1.5.1.3 GO:0000166 ... Q6FPH0 23375226
    3 4h95:A (2.6) BS02 06U 1.5.1.3 GO:0004146 ... P22906 23375226 BindingDB: IC50=60nM
    4 4h95:B (2.6) BS02 06U 1.5.1.3 GO:0004146 ... P22906 23375226 BindingDB: IC50=60nM
    5 4kak:A (1.8) BS02 06U 1.5.1.3 GO:0000900 ... P00374 24053334 MOAD: ic50=1300nM
    BindingDB: IC50=1300nM
    6 4kak:B (1.8) BS02 06U 1.5.1.3 GO:0000900 ... P00374 24053334 MOAD: ic50=1300nM
    BindingDB: IC50=1300nM
    7 4osg:A (2.7) BS02 06U N/A GO:0004146 ... N/A 25288083
    8 4osg:A (2.7) BS03 06U N/A GO:0004146 ... N/A 25288083
    9 4osg:B (2.7) BS02 06U N/A GO:0004146 ... N/A 25288083
    10 4osg:C (2.7) BS02 06U N/A GO:0004146 ... N/A 25288083
    11 4osg:D (2.7) BS02 06U N/A GO:0004146 ... N/A 25288083
    12 4xe6:X (2.692) BS01 06U 1.5.1.3 GO:0004146 ... P0A017 N/A BindingDB: IC50=19nM, Ki=2.8nM
    13 4xec:X (2.692) BS01 06U 1.5.1.3 GO:0004146 ... P0A017 26098608 BindingDB: IC50=19nM, Ki=2.8nM
    14 7t7q:X (2.2) BS02 06U 1.5.1.3 GO:0004146 ... P0A017 35143481
    15 7t7s:X (2.2) BS02 06U 1.5.1.3 GO:0004146 ... P0A017 35143481
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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