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BioLiP
Download all results in tab-seperated text for 713946 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    40801 1soo:A (2.6) BS01 H5P 6.3.4.4 GO:0000166 ... P0A7D4 8790347
    40802 1sos:A (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40803 1sos:A (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40804 1sos:B (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40805 1sos:B (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40806 1sos:C (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40807 1sos:C (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40808 1sos:D (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40809 1sos:D (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40810 1sos:E (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40811 1sos:E (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40812 1sos:F (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40813 1sos:F (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40814 1sos:G (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40815 1sos:G (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40816 1sos:H (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40817 1sos:H (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40818 1sos:I (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40819 1sos:I (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40820 1sos:J (2.5) BS01 CU 1.15.1.1 GO:0000302 ... P00441 1463506
    40821 1sos:J (2.5) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 1463506
    40822 1sow:A (1.9) BS01 OXL 1.1.1.27 GO:0003824 ... Q27797 N/A
    40823 1sow:A (1.9) BS02 NAD 1.1.1.27 GO:0003824 ... Q27797 N/A
    40824 1sow:B (1.9) BS01 OXL 1.1.1.27 GO:0003824 ... Q27797 N/A
    40825 1sow:B (1.9) BS02 NAD 1.1.1.27 GO:0003824 ... Q27797 N/A
    40826 1sox:A (1.9) BS01 SO4 1.8.3.1 GO:0005739 ... P07850 9428520
    40827 1sox:A (1.9) BS02 HEM 1.8.3.1 GO:0005739 ... P07850 9428520
    40828 1sox:B (1.9) BS01 SO4 1.8.3.1 GO:0005739 ... P07850 9428520
    40829 1sox:B (1.9) BS02 MO 1.8.3.1 GO:0005739 ... P07850 9428520
    40830 1sox:B (1.9) BS03 HEM 1.8.3.1 GO:0005739 ... P07850 9428520
    40831 1soz:A (2.4) BS01 peptide 3.4.21.107 GO:0004252 ... P0AEE3 15137941
    40832 1soz:B (2.4) BS01 peptide 3.4.21.107 GO:0004252 ... P0AEE3 15137941
    40833 1sp4:A (2.2) BS01 EP2 3.4.22.1 GO:0006508 ... P07688 15084146
    40834 1sp4:B (2.2) BS01 EP2 3.4.22.1 GO:0006508 ... P07688 15084146
    40835 1sp5:A (1.8) BS01 peptide 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03367 N/A
    40836 1sp5:B (1.8) BS01 peptide 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03367 N/A
    40837 1sp8:A (2.0) BS01 FE2 N/A GO:0003868 ... N/A 15084729
    40838 1sp8:B (2.0) BS01 FE2 N/A GO:0003868 ... N/A 15084729
    40839 1sp8:C (2.0) BS01 FE2 N/A GO:0003868 ... N/A 15084729
    40840 1sp8:D (2.0) BS01 FE2 N/A GO:0003868 ... N/A 15084729
    40841 1sp9:A (3.0) BS01 FE2 1.13.11.27 GO:0003868 ... P93836 15084729
    40842 1sp9:B (3.0) BS01 FE2 1.13.11.27 GO:0003868 ... P93836 15084729
    40843 1spa:A (2.0) BS01 NPL 2.6.1.1 GO:0003824 ... P00509 1610831
    40844 1spd:A (2.4) BS01 CU 1.15.1.1 GO:0000302 ... P00441 8351519
    40845 1spd:A (2.4) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 8351519
    40846 1spd:B (2.4) BS01 CU 1.15.1.1 GO:0000302 ... P00441 8351519
    40847 1spd:B (2.4) BS02 ZN 1.15.1.1 GO:0000302 ... P00441 8351519
    40848 1spe:A (2.0) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 8642596
    40849 1spg:A (1.95) BS01 HEM ? GO:0004601 ... P56250 8605630
    40850 1spg:B (1.95) BS01 HEM ? GO:0004601 ... P56251 8605630
    40851 1spj:A (1.7) BS01 CA 3.4.21.35 GO:0003073 ... P06870 15651049
    40852 1spu:A (2.0) BS01 CU 1.4.3.21 GO:0005507 ... P46883 9048544
    40853 1spu:A (2.0) BS02 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    40854 1spu:A (2.0) BS03 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    40855 1spu:B (2.0) BS01 CU 1.4.3.21 GO:0005507 ... P46883 9048544
    40856 1spu:B (2.0) BS02 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    40857 1spu:B (2.0) BS03 CA 1.4.3.21 GO:0005507 ... P46883 9048544
    40858 1sq3:A (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40859 1sq3:A (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40860 1sq3:A (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40861 1sq3:B (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40862 1sq3:B (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40863 1sq3:B (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40864 1sq3:C (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40865 1sq3:C (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40866 1sq3:C (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40867 1sq3:D (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40868 1sq3:D (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40869 1sq3:D (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40870 1sq3:E (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40871 1sq3:E (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40872 1sq3:E (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40873 1sq3:F (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40874 1sq3:F (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40875 1sq3:F (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40876 1sq3:G (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40877 1sq3:G (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40878 1sq3:G (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40879 1sq3:H (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40880 1sq3:H (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40881 1sq3:H (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40882 1sq3:I (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40883 1sq3:I (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40884 1sq3:I (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40885 1sq3:J (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40886 1sq3:J (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40887 1sq3:J (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40888 1sq3:K (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40889 1sq3:K (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40890 1sq3:K (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40891 1sq3:L (2.7) BS01 FE ? GO:0004322 ... O29424 15837202
    40892 1sq3:L (2.7) BS02 FE ? GO:0004322 ... O29424 15837202
    40893 1sq3:L (2.7) BS03 FE ? GO:0004322 ... O29424 15837202
    40894 1sq5:A (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40895 1sq5:A (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40896 1sq5:B (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40897 1sq5:B (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40898 1sq5:C (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40899 1sq5:C (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40900 1sq5:D (2.2) BS01 PAU 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40901 1sq5:D (2.2) BS02 ADP 2.7.1.33 GO:0004594 ... P0A6I3 15136582
    40902 1sq6:A (2.4) BS01 SO4 2.4.2.1
    2.4.2.44
    GO:0003824 ... Q8I3X4 16131758
    40903 1sqa:A (2.0) BS01 UI1 3.4.21.73 GO:0004252 ... P00749 15149645 MOAD: Ki=0.00062uM
    PDBbind: -logKd/Ki=9.21, Ki=0.62nM
    BindingDB: IC50=620nM, Ki=0.620000nM
    40904 1sqb:C (2.69) BS01 HEM 1.10.2.2 GO:0005739 ... P00157 15312779
    40905 1sqb:C (2.69) BS02 HEM 1.10.2.2 GO:0005739 ... P00157 15312779
    40906 1sqb:C (2.69) BS03 AZO 1.10.2.2 GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=7.95, IC50=11.2nM
    40907 1sqd:A (1.8) BS01 FE 1.13.11.27 GO:0003868 ... P93836 15301540
    40908 1sqf:A (2.1) BS01 SAM 2.1.1.176 GO:0001510 ... P36929 14656444
    40909 1sqi:A (2.15) BS01 FE 1.13.11.27 GO:0000139 ... P32755 15301540
    40910 1sqi:A (2.15) BS02 869 1.13.11.27 GO:0000139 ... P32755 15301540 MOAD: ic50<20nM
    PDBbind: -logKd/Ki=7.70, IC50<20nM
    40911 1sqi:B (2.15) BS01 FE 1.13.11.27 GO:0000139 ... P32755 15301540
    40912 1sqi:B (2.15) BS02 869 1.13.11.27 GO:0000139 ... P32755 15301540 MOAD: ic50<20nM
    40913 1sqk:A (2.5) BS01 peptide 3.6.4.- GO:0000287 ... P68135 15163409
    40914 1sqk:A (2.5) BS02 ADP 3.6.4.- GO:0000287 ... P68135 15163409
    40915 1sqk:A (2.5) BS03 LAR 3.6.4.- GO:0000287 ... P68135 15163409
    40916 1sqm:A (2.3) BS01 ZN 3.3.2.6
    3.4.11.4
    GO:0003723 ... P09960 15078870
    40917 1sqo:A (1.84) BS01 UI2 3.4.21.73 GO:0004252 ... P00749 15149645 MOAD: Ki=0.035uM
    PDBbind: -logKd/Ki=7.46, Ki=0.035uM
    BindingDB: Ki=32nM
    40918 1sqp:C (2.7) BS01 HEC ? GO:0005739 ... P00157 15312779
    40919 1sqp:C (2.7) BS02 HEC ? GO:0005739 ... P00157 15312779
    40920 1sqp:C (2.7) BS03 MYX ? GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=8.20, IC50=6.3nM
    40921 1sqp:J (2.7) BS01 PLX 1.10.2.2 GO:0005739 ... P00130 15312779
    40922 1sqq:C (3.0) BS01 HEC ? GO:0005739 ... P00157 15312779
    40923 1sqq:C (3.0) BS02 HEC ? GO:0005739 ... P00157 15312779
    40924 1sqq:C (3.0) BS03 UQ2 ? GO:0005739 ... P00157 15312779
    40925 1sqq:C (3.0) BS04 OST ? GO:0005739 ... P00157 15312779 PDBbind: -logKd/Ki=7.82, Kd=15nM
    40926 1sqt:A (1.9) BS01 UI3 3.4.21.73 GO:0004252 ... P00749 15149645 MOAD: Ki=0.63uM
    PDBbind: -logKd/Ki=6.20, Ki=0.63uM
    BindingDB: Ki=630nM
    40927 1sqv:C (2.85) BS01 HEC 1.10.2.2 GO:0005739 ... P00157 15312779
    40928 1sqv:C (2.85) BS02 HEC 1.10.2.2 GO:0005739 ... P00157 15312779
    40929 1sqv:C (2.85) BS03 UHD 1.10.2.2 GO:0005739 ... P00157 15312779
    40930 1sqv:C (2.85) BS04 UQ2 1.10.2.2 GO:0005739 ... P00157 15312779
    40931 1sqx:C (2.6) BS01 UQ2 ? GO:0005739 ... P00157 15312779
    40932 1sqx:C (2.6) BS02 HEC ? GO:0005739 ... P00157 15312779
    40933 1sqx:C (2.6) BS03 HEC ? GO:0005739 ... P00157 15312779
    40934 1sqx:C (2.6) BS04 SMA ? GO:0005739 ... P00157 15312779
    40935 1sqy:A (2.5) BS01 FE 3.4.21.- GO:0001503 ... P02788 N/A
    40936 1sqy:A (2.5) BS02 FE 3.4.21.- GO:0001503 ... P02788 N/A
    40937 1sqy:A (2.5) BS03 CO3 3.4.21.- GO:0001503 ... P02788 N/A
    40938 1sqy:A (2.5) BS04 CO3 3.4.21.- GO:0001503 ... P02788 N/A
    40939 1sqz:A (1.2) BS01 peptide 3.1.1.4 GO:0004623 ... P59071 N/A
    40940 1sr5:A (3.1) BS01 YYB ? GO:0002020 ... P01008 15311268
    40941 1sr5:A (3.1) BS02 U9J ? GO:0002020 ... P01008 15311268
    40942 1sr5:A (3.1) BS03 GU6 ? GO:0002020 ... P01008 15311268
    40943 1sr5:A (3.1) BS04 U9G ? GO:0002020 ... P01008 15311268
    40944 1sr9:A (2.0) BS01 ZN 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    40945 1sr9:A (2.0) BS02 KIV 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    40946 1sr9:B (2.0) BS01 ZN 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    40947 1sr9:B (2.0) BS02 KIV 2.3.3.13 GO:0000287 ... P9WQB3 15159544
    40948 1srd:A (2.0) BS01 CU 1.15.1.1 GO:0005507 ... P07505 1880134
    40949 1srd:A (2.0) BS02 ZN 1.15.1.1 GO:0005507 ... P07505 1880134
    40950 1srd:B (2.0) BS01 CU 1.15.1.1 GO:0005507 ... P07505 1880134
    40951 1srd:B (2.0) BS02 ZN 1.15.1.1 GO:0005507 ... P07505 1880134
    40952 1srd:C (2.0) BS01 CU 1.15.1.1 GO:0005507 ... P07505 1880134
    40953 1srd:C (2.0) BS02 ZN 1.15.1.1 GO:0005507 ... P07505 1880134
    40954 1srd:D (2.0) BS01 CU 1.15.1.1 GO:0005507 ... P07505 1880134
    40955 1srd:D (2.0) BS02 ZN 1.15.1.1 GO:0005507 ... P07505 1880134
    40956 1srn:A (1.8) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 3680234
    40957 1srp:A (2.0) BS01 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40958 1srp:A (2.0) BS02 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40959 1srp:A (2.0) BS03 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40960 1srp:A (2.0) BS04 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40961 1srp:A (2.0) BS05 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40962 1srp:A (2.0) BS06 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40963 1srp:A (2.0) BS07 CA 3.4.24.40 GO:0004222 ... P07268 8797082
    40964 1srp:A (2.0) BS08 ZN 3.4.24.40 GO:0004222 ... P07268 8797082
    40965 1srr:A (1.9) BS01 CA 2.7.-.- GO:0000160 ... P06628 8805550
    40966 1srr:C (1.9) BS01 CA 2.7.-.- GO:0000160 ... P06628 8805550
    40967 1srs:A (3.2) BS01 dna ? GO:0000981 ... P11831 7637780
    40968 1srs:A (3.2) BS02 dna ? GO:0000981 ... P11831 7637780
    40969 1srs:B (3.2) BS01 dna ? GO:0000981 ... P11831 7637780
    40970 1srs:B (3.2) BS02 dna ? GO:0000981 ... P11831 7637780
    40971 1ss4:B (1.84) BS01 GSH ? GO:0004493 ... Q81F54 N/A
    40972 1ssa:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 8142897
    40973 1ssb:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 8142897
    40974 1ssc:A (2.0) BS01 peptide 4.6.1.18 GO:0003676 ... P61823 15299768
    40975 1ssg:A (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    40976 1ssg:B (2.9) BS01 PGA 4.2.3.3
    5.3.1.1
    GO:0004807 ... P00940 15166315
    40977 1ssh:A (1.4) BS01 peptide ? GO:0006897 ... P43603 N/A
    40978 1ssp:E (1.9) BS01 dna 3.2.2.27 GO:0004844 ... P13051 9724657 PDBbind: Kd=48nM
    40979 1ssp:E (1.9) BS02 URA 3.2.2.27 GO:0004844 ... P13051 9724657
    40980 1ssq:A (1.85) BS01 CYS 2.3.1.30 GO:0005737 ... P43886 15147185 MOAD: Ki=1uM
    PDBbind: -logKd/Ki=6.00, Ki=1uM
    40981 1ssq:D (1.85) BS01 CYS 2.3.1.30 GO:0005737 ... P43886 15147185
    40982 1sst:A (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40983 1sst:A (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40984 1sst:B (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40985 1sst:B (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40986 1sst:C (2.0) BS01 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40987 1sst:C (2.0) BS02 COA 2.3.1.30 GO:0005737 ... P43886 15147185
    40988 1ssx:A (0.83) BS01 SO4 3.4.21.12 GO:0004252 ... P00778 15111063
    40989 1ssx:A (0.83) BS02 SO4 3.4.21.12 GO:0004252 ... P00778 15111063
    40990 1ssx:A (0.83) BS03 SO4 3.4.21.12 GO:0004252 ... P00778 15111063
    40991 1st0:A (1.9) BS01 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    40992 1st0:B (1.9) BS01 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    40993 1st0:B (1.9) BS02 GTG 3.6.1.59 GO:0000288 ... Q96C86 15068804
    40994 1st2:A (2.0) BS01 CA 3.4.21.62 GO:0004252 ... P00782 3286644
    40995 1st2:A (2.0) BS02 CA 3.4.21.62 GO:0004252 ... P00782 3286644
    40996 1st3:A (1.4) BS01 CA 3.4.21.62 GO:0004252 ... P29599 1453465
    40997 1st3:A (1.4) BS02 CA 3.4.21.62 GO:0004252 ... P29599 1453465
    40998 1st4:A (2.02) BS01 GTA 3.6.1.59 GO:0000288 ... Q96C86 15068804
    40999 1st4:B (2.02) BS01 GTA 3.6.1.59 GO:0000288 ... Q96C86 15068804
    41000 1st4:B (2.02) BS02 GTA 3.6.1.59 GO:0000288 ... Q96C86 15068804

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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