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BioLiP
Download all results in tab-seperated text for 713946 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    23801 1l8a:A (1.85) BS01 TPP 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23802 1l8a:A (1.85) BS02 MG 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23803 1l8a:A (1.85) BS03 TPP 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23804 1l8a:B (1.85) BS01 MG 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23805 1l8a:B (1.85) BS02 TPP 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23806 1l8a:B (1.85) BS03 TPP 1.2.4.1 GO:0000287 ... P0AFG8 11955070
    23807 1l8b:A (1.8) BS01 MGP ? GO:0003723 ... P63073 12054859 MOAD: Kd=0.14uM
    BindingDB: Kd=10nM
    23808 1l8b:B (1.8) BS01 MGP ? GO:0003723 ... P63073 12054859 MOAD: Kd=0.14uM
    BindingDB: Kd=10nM
    23809 1l8c:A (-1.00) BS01 ZN 2.3.1.-
    2.3.1.48
    GO:0004402 ... P45481 11959977
    23810 1l8c:A (-1.00) BS02 ZN 2.3.1.-
    2.3.1.48
    GO:0004402 ... P45481 11959977
    23811 1l8c:A (-1.00) BS03 ZN 2.3.1.-
    2.3.1.48
    GO:0004402 ... P45481 11959977
    23812 1l8g:A (2.5) BS01 DBD 3.1.3.48 GO:0004725 ... P18031 11732900 PDBbind: -logKd/Ki=6.22, Ki=0.6uM
    BindingDB: Ki=1100nM
    23813 1l8l:A (2.51) BS01 APO 3.1.3.3 GO:0000287 ... P78330 12213811
    23814 1l8l:B (2.51) BS01 APO 3.1.3.3 GO:0000287 ... P78330 12213811
    23815 1l8n:A (1.5) BS01 XYP 3.2.1.131 GO:0004553 ... Q8VVD2 14573597
    23816 1l8n:A (1.5) BS02 XYP 3.2.1.131 GO:0004553 ... Q8VVD2 14573597
    23817 1l8n:A (1.5) BS03 GCW 3.2.1.131 GO:0004553 ... Q8VVD2 14573597
    23818 1l8o:A (2.8) BS01 PO4 3.1.3.3 GO:0000287 ... P78330 12213811
    23819 1l8o:A (2.8) BS02 SER 3.1.3.3 GO:0000287 ... P78330 12213811
    23820 1l8o:B (2.8) BS01 PO4 3.1.3.3 GO:0000287 ... P78330 12213811
    23821 1l8o:B (2.8) BS02 SER 3.1.3.3 GO:0000287 ... P78330 12213811
    23822 1l8p:A (2.1) BS01 MG 4.2.1.11 GO:0000015 ... P00924 12054465
    23823 1l8p:A (2.1) BS02 PAH 4.2.1.11 GO:0000015 ... P00924 12054465
    23824 1l8p:B (2.1) BS01 MG 4.2.1.11 GO:0000015 ... P00924 12054465
    23825 1l8p:B (2.1) BS02 PAH 4.2.1.11 GO:0000015 ... P00924 12054465
    23826 1l8p:C (2.1) BS01 MG 4.2.1.11 GO:0000015 ... P00924 12054465
    23827 1l8p:C (2.1) BS02 PAH 4.2.1.11 GO:0000015 ... P00924 12054465
    23828 1l8p:D (2.1) BS01 MG 4.2.1.11 GO:0000015 ... P00924 12054465
    23829 1l8p:D (2.1) BS02 PAH 4.2.1.11 GO:0000015 ... P00924 12054465
    23830 1l8q:A (2.7) BS01 ADP ? GO:0003677 ... O66659 12234917
    23831 1l8s:A (1.55) BS01 CA 3.1.1.4 GO:0002446 ... P00592 12475227
    23832 1l8s:A (1.55) BS02 PO4 3.1.1.4 GO:0002446 ... P00592 12475227
    23833 1l8s:A (1.55) BS03 PO4 3.1.1.4 GO:0002446 ... P00592 12475227
    23834 1l8s:A (1.55) BS04 ACT 3.1.1.4 GO:0002446 ... P00592 12475227
    23835 1l8s:B (1.55) BS01 PO4 3.1.1.4 GO:0002446 ... P00592 12475227
    23836 1l8s:B (1.55) BS02 CA 3.1.1.4 GO:0002446 ... P00592 12475227
    23837 1l8s:B (1.55) BS03 PO4 3.1.1.4 GO:0002446 ... P00592 12475227
    23838 1l8s:B (1.55) BS04 PO4 3.1.1.4 GO:0002446 ... P00592 12475227
    23839 1l8s:B (1.55) BS05 LPE 3.1.1.4 GO:0002446 ... P00592 12475227
    23840 1l8t:A (2.4) BS01 MG 2.7.1.95 GO:0005524 ... P0A3Y5 12006485
    23841 1l8t:A (2.4) BS02 ADP 2.7.1.95 GO:0005524 ... P0A3Y5 12006485
    23842 1l8t:A (2.4) BS03 KAN 2.7.1.95 GO:0005524 ... P0A3Y5 12006485
    23843 1l8x:B (2.7) BS01 CO 4.98.1.1 GO:0004325 ... P16622 12427010
    23844 1l9a:A (2.9) BS01 rna ? GO:0003723 ... Q58440 12086622
    23845 1l9b:C (2.4) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    23846 1l9b:L (2.4) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    23847 1l9b:L (2.4) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    23848 1l9b:L (2.4) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    23849 1l9b:L (2.4) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    23850 1l9b:L (2.4) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    23851 1l9b:L (2.4) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    23852 1l9b:M (2.4) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    23853 1l9b:M (2.4) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    23854 1l9b:M (2.4) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    23855 1l9b:M (2.4) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    23856 1l9b:M (2.4) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    23857 1l9b:M (2.4) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    23858 1l9b:M (2.4) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    23859 1l9g:A (2.5) BS01 SF4 3.2.2.27 GO:0004844 ... Q9WYY1 N/A
    23860 1l9h:A (2.6) BS01 ZN ? GO:0000139 ... P02699 11972040
    23861 1l9h:A (2.6) BS02 ZN ? GO:0000139 ... P02699 11972040
    23862 1l9h:A (2.6) BS03 ZN ? GO:0000139 ... P02699 11972040
    23863 1l9h:A (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    23864 1l9h:B (2.6) BS01 ZN ? GO:0000139 ... P02699 11972040
    23865 1l9h:B (2.6) BS02 ZN ? GO:0000139 ... P02699 11972040
    23866 1l9h:B (2.6) BS03 ZN ? GO:0000139 ... P02699 11972040
    23867 1l9h:B (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    23868 1l9j:C (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    23869 1l9j:D (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    23870 1l9j:L (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    23871 1l9j:L (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    23872 1l9j:L (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    23873 1l9j:L (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    23874 1l9j:L (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    23875 1l9j:L (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    23876 1l9j:M (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    23877 1l9j:M (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    23878 1l9j:M (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    23879 1l9j:M (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    23880 1l9j:M (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    23881 1l9j:M (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    23882 1l9j:M (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    23883 1l9j:R (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    23884 1l9j:R (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    23885 1l9j:R (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    23886 1l9j:R (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    23887 1l9j:R (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    23888 1l9j:R (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    23889 1l9j:S (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    23890 1l9j:S (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    23891 1l9j:S (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    23892 1l9j:S (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    23893 1l9j:S (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    23894 1l9j:S (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    23895 1l9j:S (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    23896 1l9k:A (2.4) BS01 SAH 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13
    GO:0003968 ... P12823 12032088
    23897 1l9l:A (0.92) BS01 SO4 ? GO:0042742 ... P22749 12488100
    23898 1l9l:A (0.92) BS02 SO4 ? GO:0042742 ... P22749 12488100
    23899 1l9l:A (0.92) BS03 SO4 ? GO:0042742 ... P22749 12488100
    23900 1l9m:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23901 1l9m:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23902 1l9n:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23903 1l9n:A (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23904 1l9n:A (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23905 1l9n:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23906 1l9n:B (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23907 1l9n:B (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    23908 1l9o:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23909 1l9o:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23910 1l9o:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23911 1l9o:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23912 1l9o:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23913 1l9o:C (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23914 1l9o:C (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23915 1l9p:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23916 1l9p:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23917 1l9p:B (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23918 1l9p:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23919 1l9p:C (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23920 1l9p:C (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23921 1l9q:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23922 1l9q:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23923 1l9q:A (1.7) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23924 1l9q:A (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23925 1l9q:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23926 1l9q:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23927 1l9q:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23928 1l9q:B (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23929 1l9q:C (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23930 1l9q:C (1.7) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23931 1l9q:C (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23932 1l9q:C (1.7) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23933 1l9r:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23934 1l9r:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23935 1l9r:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23936 1l9r:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23937 1l9r:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23938 1l9r:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23939 1l9r:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23940 1l9r:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23941 1l9r:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23942 1l9s:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23943 1l9s:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23944 1l9s:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23945 1l9s:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23946 1l9s:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23947 1l9s:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23948 1l9s:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23949 1l9s:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23950 1l9s:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23951 1l9t:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23952 1l9t:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23953 1l9t:A (1.75) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23954 1l9t:A (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23955 1l9t:B (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23956 1l9t:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23957 1l9t:B (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23958 1l9t:B (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23959 1l9t:C (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23960 1l9t:C (1.75) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    23961 1l9t:C (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23962 1l9t:C (1.75) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    23963 1l9w:A (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    23964 1l9w:B (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    23965 1l9w:C (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    23966 1l9w:D (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    23967 1la0:A (-1.00) BS01 CA ? GO:0003009 ... P09860 12147696
    23968 1la0:A (-1.00) BS02 CA ? GO:0003009 ... P09860 12147696
    23969 1la0:A (-1.00) BS03 CA ? GO:0003009 ... P09860 12147696
    23970 1la2:A (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    23971 1la2:B (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    23972 1la2:C (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    23973 1la2:D (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    23974 1la3:A (-1.00) BS01 CA ? GO:0001750 ... P21457 11980481
    23975 1la6:A (2.0) BS01 HEM ? GO:0004601 ... P45718 12093902
    23976 1la6:B (2.0) BS01 HEM ? GO:0004601 ... P45720 12093902
    23977 1laf:E (2.06) BS01 ARG ? GO:0006865 ... P02911 7929349 MOAD: Kd=14nM
    PDBbind: -logKd/Ki=7.85, Kd=14nM
    23978 1lag:E (2.06) BS01 HIS ? GO:0006865 ... P02911 7929349 MOAD: Kd=500nM
    PDBbind: -logKd/Ki=6.30, Kd=500nM
    23979 1lah:E (2.06) BS01 ORN ? GO:0006865 ... P02911 7929349 MOAD: Kd=30nM
    PDBbind: -logKd/Ki=7.52, Kd=30nM
    23980 1lam:A (1.6) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    23981 1lam:A (1.6) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    23982 1lam:A (1.6) BS03 CO3 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    23983 1lan:A (1.9) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    23984 1lan:A (1.9) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    23985 1lan:A (1.9) BS03 LEU 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088 MOAD: Ki=60nM
    PDBbind: -logKd/Ki=7.22, Ki=60nM
    23986 1lap:A (2.7) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    23987 1lap:A (2.7) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    23988 1lat:A (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    23989 1lat:A (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    23990 1lat:A (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    23991 1lat:A (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    23992 1lat:B (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    23993 1lat:B (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    23994 1lat:B (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    23995 1lat:B (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    23996 1lau:E (1.8) BS01 dna 3.2.2.27 GO:0004844 ... P10186 7845459
    23997 1lax:A (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    23998 1lax:A (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028
    23999 1lax:C (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    24000 1lax:C (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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