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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    601 1a9x:G (1.8) BS07 ORN 6.3.4.16
    6.3.5.5
    GO:0000166 ... P00968 9636022
    602 1a9y:A (1.8) BS01 NAD 5.1.3.2 GO:0003978 ... P09147 9708982
    603 1a9y:A (1.8) BS02 UPG 5.1.3.2 GO:0003978 ... P09147 9708982
    604 1a9z:A (1.9) BS01 NAD 5.1.3.2 GO:0003978 ... P09147 9708982
    605 1a9z:A (1.9) BS02 UPG 5.1.3.2 GO:0003978 ... P09147 9708982
    606 1aa1:B (2.2) BS01 MG 4.1.1.39 GO:0000287 ... P00875 9092835
    607 1aa1:E (2.2) BS01 MG 4.1.1.39 GO:0000287 ... P00875 9092835
    608 1aa1:H (2.2) BS01 MG 4.1.1.39 GO:0000287 ... P00875 9092835
    609 1aa1:L (2.2) BS01 MG 4.1.1.39 GO:0000287 ... P00875 9092835
    610 1aa6:A (2.3) BS01 SF4 1.17.98.4 GO:0003954 ... P07658 9036855
    611 1aa6:A (2.3) BS02 MGD 1.17.98.4 GO:0003954 ... P07658 9036855
    612 1aa6:A (2.3) BS03 MGD 1.17.98.4 GO:0003954 ... P07658 9036855
    613 1aa9:A (-1.00) BS01 MG 3.6.5.2 GO:0000139 ... P01112 9230043
    614 1aa9:A (-1.00) BS02 GDP 3.6.5.2 GO:0000139 ... P01112 9230043
    615 1aac:A (1.31) BS01 CU ? GO:0005507 ... P22364 15299631
    616 1aam:A (2.8) BS01 PLP 2.6.1.1 GO:0003824 ... P00509 7909946
    617 1aan:A (2.0) BS01 CU ? GO:0005507 ... P22364 8495197
    618 1aaw:A (2.4) BS01 PLP 2.6.1.1 GO:0003824 ... P00509 7909946
    619 1abb:A (2.8) BS01 SO4 2.4.1.1 GO:0000166 ... P00489 1304390
    620 1abb:A (2.8) BS02 PDP 2.4.1.1 GO:0000166 ... P00489 1304390
    621 1abb:A (2.8) BS03 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    622 1abb:A (2.8) BS04 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    623 1abb:B (2.8) BS01 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    624 1abb:B (2.8) BS02 SO4 2.4.1.1 GO:0000166 ... P00489 1304390
    625 1abb:B (2.8) BS03 PDP 2.4.1.1 GO:0000166 ... P00489 1304390
    626 1abb:B (2.8) BS04 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    627 1abb:C (2.8) BS01 SO4 2.4.1.1 GO:0000166 ... P00489 1304390
    628 1abb:C (2.8) BS02 PDP 2.4.1.1 GO:0000166 ... P00489 1304390
    629 1abb:C (2.8) BS03 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    630 1abb:C (2.8) BS04 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    631 1abb:D (2.8) BS01 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    632 1abb:D (2.8) BS02 SO4 2.4.1.1 GO:0000166 ... P00489 1304390
    633 1abb:D (2.8) BS03 PDP 2.4.1.1 GO:0000166 ... P00489 1304390
    634 1abb:D (2.8) BS04 IMP 2.4.1.1 GO:0000166 ... P00489 1304390
    635 1abe:A (1.7) BS01 ARA ? GO:0015407 ... P02924 6379466
    636 1abe:A (1.7) BS02 ARB ? GO:0015407 ... P02924 6379466
    637 1abf:A (1.9) BS01 FCA ? GO:0015407 ... P02924 2818726 MOAD: Kd=3.8uM
    PDBbind: -logKd/Ki=5.42, Kd=3.8uM
    638 1abf:A (1.9) BS02 FCB ? GO:0015407 ... P02924 2818726 MOAD: Kd=3.8uM
    639 1abn:A (2.4) BS01 NDP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 1447221
    640 1abs:A (1.5) BS01 HEM 1.11.1.-
    1.7.-.-
    GO:0004601 ... P02185 7935843
    641 1abt:A (-1.00) BS01 peptide ? GO:0005515 ... P60615 8241115
    642 1abw:A (2.0) BS01 MET ? GO:0004601 ... P69905 9032082
    643 1abw:A (2.0) BS02 LEU ? GO:0004601 ... P69905 9032082
    644 1abw:A (2.0) BS03 MET ? GO:0004601 ... P69905 9032082
    645 1abw:A (2.0) BS04 LEU ? GO:0004601 ... P69905 9032082
    646 1abw:A (2.0) BS05 HEM ? GO:0004601 ... P69905 9032082
    647 1abw:A (2.0) BS06 HEM ? GO:0004601 ... P69905 9032082
    648 1abw:B (2.0) BS01 HEM ? GO:0004601 ... P68871 9032082
    649 1abw:D (2.0) BS01 HEM ? GO:0004601 ... P68871 9032082
    650 1aby:A (2.6) BS01 HEM ? GO:0004601 ... P69905 9032082
    651 1aby:A (2.6) BS02 HEM ? GO:0004601 ... P69905 9032082
    652 1aby:B (2.6) BS01 HEM ? GO:0004601 ... P68871 9032082
    653 1aby:D (2.6) BS01 HEM ? GO:0004601 ... P68871 9032082
    654 1aca:A (-1.00) BS01 COA ? GO:0000062 ... P07107 8503960
    655 1acc:A (2.1) BS01 CA ? GO:0005515 ... P13423 9039918
    656 1acc:A (2.1) BS02 CA ? GO:0005515 ... P13423 9039918
    657 1acj:A (2.8) BS01 THA 3.1.1.7 GO:0001507 ... P04058 8415649 PDBbind: -logKd/Ki=8.09, IC50=8.2nM
    BindingDB: IC50=29nM, Ki=40nM
    658 1acl:A (2.8) BS01 DME 3.1.1.7 GO:0001507 ... P04058 8415649
    659 1acm:A (2.8) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 1303763
    660 1acm:B (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 1303763
    661 1acm:C (2.8) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 1303763
    662 1acm:D (2.8) BS01 ZN ? GO:0005515 ... P0A7F3 1303763
    663 1aco:A (2.05) BS01 TRA 4.2.1.3 GO:0003994 ... P20004 8151704
    664 1aco:A (2.05) BS02 SF4 4.2.1.3 GO:0003994 ... P20004 8151704
    665 1ad3:A (2.6) BS01 NAD 1.2.1.5 GO:0001666 ... P11883 9095201
    666 1ad3:B (2.6) BS01 NAD 1.2.1.5 GO:0001666 ... P11883 9095201
    667 1ad4:A (2.4) BS01 HH2 2.5.1.15 GO:0004156 ... O05701 9149138
    668 1adb:A (2.4) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    669 1adb:A (2.4) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    670 1adb:A (2.4) BS03 CND 1.1.1.1 GO:0004022 ... P00327 7918390
    671 1adb:B (2.4) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    672 1adb:B (2.4) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    673 1adb:B (2.4) BS03 CND 1.1.1.1 GO:0004022 ... P00327 7918390
    674 1adc:A (2.7) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    675 1adc:A (2.7) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    676 1adc:A (2.7) BS03 PAD 1.1.1.1 GO:0004022 ... P00327 7918390
    677 1adc:B (2.7) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    678 1adc:B (2.7) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 7918390
    679 1adc:B (2.7) BS03 PAD 1.1.1.1 GO:0004022 ... P00327 7918390
    680 1add:A (2.4) BS01 ZN 3.5.4.4 GO:0000255 ... P03958 8439534
    681 1add:A (2.4) BS02 1DA 3.5.4.4 GO:0000255 ... P03958 8439534 MOAD: Ki=0.18uM
    PDBbind: -logKd/Ki=6.74, Ki=0.18uM
    682 1adf:A (2.9) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 8286346
    683 1adf:A (2.9) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 8286346
    684 1adf:A (2.9) BS03 TAD 1.1.1.1 GO:0004022 ... P00327 8286346
    685 1adg:A (2.7) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 8286346
    686 1adg:A (2.7) BS02 SAD 1.1.1.1 GO:0004022 ... P00327 8286346
    687 1adj:A (2.7) BS01 HIS 6.1.1.21 GO:0004812 ... P56194 9115984
    688 1adj:B (2.7) BS01 HIS 6.1.1.21 GO:0004812 ... P56194 9115984
    689 1adj:C (2.7) BS01 HIS 6.1.1.21 GO:0004812 ... P56194 9115984
    690 1adj:D (2.7) BS01 HIS 6.1.1.21 GO:0004812 ... P56194 9115984
    691 1adl:A (1.6) BS01 ACD ? GO:0005324 ... P04117 7929228 MOAD: Kd=4.4uM
    PDBbind: -logKd/Ki=5.36, Kd=4.4uM
    692 1ads:A (1.65) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 1621098
    693 1adw:A (2.5) BS01 CU ? GO:0005507 ... P80401 7583671
    694 1adw:B (2.5) BS01 CU ? GO:0005507 ... P80401 7583671
    695 1ady:A (2.8) BS01 HAM 6.1.1.21 GO:0004812 ... P56194 9115984
    696 1ady:B (2.8) BS01 HAM 6.1.1.21 GO:0004812 ... P56194 9115984
    697 1ady:C (2.8) BS01 HAM 6.1.1.21 GO:0004812 ... P56194 9115984
    698 1ady:D (2.8) BS01 HAM 6.1.1.21 GO:0004812 ... P56194 9115984
    699 1ae4:A (2.4) BS01 NAP 1.1.1.19
    1.1.1.2
    1.1.1.20
    1.1.1.372
    1.1.1.54
    1.6.-.-
    GO:0004032 ... P50578 9329083
    700 1aei:A (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    701 1aei:A (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    702 1aei:A (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    703 1aei:A (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    704 1aei:B (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    705 1aei:B (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    706 1aei:B (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    707 1aei:B (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    708 1aei:C (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    709 1aei:C (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    710 1aei:C (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    711 1aei:C (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    712 1aei:D (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    713 1aei:D (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    714 1aei:D (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    715 1aei:D (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    716 1aei:E (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    717 1aei:E (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    718 1aei:E (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    719 1aei:E (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    720 1aei:F (2.8) BS01 CA ? GO:0005509 ... P26256 7477411
    721 1aei:F (2.8) BS02 CA ? GO:0005509 ... P26256 7477411
    722 1aei:F (2.8) BS03 CA ? GO:0005509 ... P26256 7477411
    723 1aei:F (2.8) BS04 CA ? GO:0005509 ... P26256 7477411
    724 1af0:A (1.8) BS01 ZN 3.4.24.40 GO:0001907 ... P23694 N/A
    725 1af0:A (1.8) BS02 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    726 1af0:A (1.8) BS03 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    727 1af0:A (1.8) BS04 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    728 1af0:A (1.8) BS05 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    729 1af0:A (1.8) BS06 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    730 1af0:A (1.8) BS07 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    731 1af0:A (1.8) BS08 CA 3.4.24.40 GO:0001907 ... P23694 N/A
    732 1af0:A (1.8) BS09 0Z9 3.4.24.40 GO:0001907 ... P23694 N/A
    733 1af2:A (2.3) BS01 ZN 3.5.4.5 GO:0001884 ... P0ABF6 9125497
    734 1af2:A (2.3) BS02 U 3.5.4.5 GO:0001884 ... P0ABF6 9125497 PDBbind: -logKd/Ki=3.10, Ki=0.8mM
    735 1af6:A (2.4) BS01 GLC ? GO:0001618 ... P02943 9299337 PDBbind: -logKd/Ki=1.82, Kd=15mM
    736 1af6:A (2.4) BS02 FRU ? GO:0001618 ... P02943 9299337
    737 1af6:B (2.4) BS01 GLC ? GO:0001618 ... P02943 9299337 PDBbind: -logKd/Ki=1.82, Kd=15mM
    738 1af6:B (2.4) BS02 FRU ? GO:0001618 ... P02943 9299337
    739 1af6:C (2.4) BS01 GLC ? GO:0001618 ... P02943 9299337
    740 1af6:C (2.4) BS02 FRU ? GO:0001618 ... P02943 9299337
    741 1afc:A (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    742 1afc:A (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    743 1afc:B (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    744 1afc:B (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    745 1afc:C (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    746 1afc:C (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    747 1afc:D (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    748 1afc:D (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    749 1afc:E (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    750 1afc:E (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    751 1afc:F (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    752 1afc:F (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    753 1afc:G (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    754 1afc:G (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    755 1afc:H (2.7) BS01 GU4 ? GO:0001525 ... P03968 7520817
    756 1afc:H (2.7) BS02 YYJ ? GO:0001525 ... P03968 7520817
    757 1afj:A (-1.00) BS01 HG ? GO:0015097 ... P04129 9188683
    758 1afk:A (1.7) BS01 PAP 4.6.1.18 GO:0003676 ... P61823 9154942 MOAD: Ki=240nM
    PDBbind: -logKd/Ki=6.62, Ki=240nM
    759 1afk:B (1.7) BS01 PAP 4.6.1.18 GO:0003676 ... P61823 9154942 MOAD: Ki=240nM
    760 1afl:A (1.7) BS01 ATR 4.6.1.18 GO:0003676 ... P61823 9154942 MOAD: Ki=520nM
    PDBbind: -logKd/Ki=6.28, Ki=520nM
    761 1afl:B (1.7) BS01 ATR 4.6.1.18 GO:0003676 ... P61823 9154942 MOAD: Ki=520nM
    762 1afs:A (2.5) BS01 NAP 1.1.1.50 GO:0004032 ... P23457 9261071
    763 1afs:A (2.5) BS02 TES 1.1.1.50 GO:0004032 ... P23457 9261071
    764 1afs:B (2.5) BS01 NAP 1.1.1.50 GO:0004032 ... P23457 9261071
    765 1afs:B (2.5) BS02 TES 1.1.1.50 GO:0004032 ... P23457 9261071
    766 1ag1:T (2.36) BS01 PO4 5.3.1.1 GO:0004807 ... P04789 2040290
    767 1ag9:A (1.8) BS01 CA ? GO:0000166 ... P61949 9416602
    768 1ag9:A (1.8) BS02 FMN ? GO:0000166 ... P61949 9416602 MOAD: Kd=1nM
    PDBbind: -logKd/Ki=9.00, Kd=1nM
    769 1ag9:A (1.8) BS03 BTB ? GO:0000166 ... P61949 9416602
    770 1ag9:B (1.8) BS01 CA ? GO:0000166 ... P61949 9416602
    771 1ag9:B (1.8) BS02 FMN ? GO:0000166 ... P61949 9416602 MOAD: Kd=1nM
    PDBbind: -logKd/Ki=9.00, Kd=1nM
    772 1ag9:B (1.8) BS03 BTB ? GO:0000166 ... P61949 9416602
    773 1agn:A (3.0) BS01 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    774 1agn:A (3.0) BS02 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    775 1agn:A (3.0) BS03 ACT 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    776 1agn:A (3.0) BS04 NAD 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    777 1agn:B (3.0) BS01 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    778 1agn:B (3.0) BS02 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    779 1agn:B (3.0) BS03 ACT 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    780 1agn:B (3.0) BS04 NAD 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    781 1agn:C (3.0) BS01 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    782 1agn:C (3.0) BS02 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    783 1agn:C (3.0) BS03 NAD 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    784 1agn:D (3.0) BS01 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    785 1agn:D (3.0) BS02 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    786 1agn:D (3.0) BS03 ZN 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    787 1agn:D (3.0) BS04 ACT 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    788 1agn:D (3.0) BS05 NAD 1.1.1.1
    1.1.1.105
    1.1.1.66
    GO:0001523 ... P40394 9228021
    789 1agp:A (2.3) BS01 MG 3.6.5.2 GO:0003924 ... P01112 8357792
    790 1agp:A (2.3) BS02 GNP 3.6.5.2 GO:0003924 ... P01112 8357792
    791 1agr:A (2.8) BS01 MG ? GO:0000287 ... P10824 9108480
    792 1agr:A (2.8) BS02 ALF ? GO:0000287 ... P10824 9108480
    793 1agr:A (2.8) BS03 GDP ? GO:0000287 ... P10824 9108480
    794 1agr:D (2.8) BS01 MG ? GO:0000287 ... P10824 9108480
    795 1agr:D (2.8) BS02 ALF ? GO:0000287 ... P10824 9108480
    796 1agr:D (2.8) BS03 GDP ? GO:0000287 ... P10824 9108480
    797 1ah0:A (2.3) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P80276 9195881
    798 1ah0:A (2.3) BS02 SBI 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P80276 9195881 BindingDB: IC50=1100nM
    799 1ah3:A (2.3) BS01 NAP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P80276 9195881
    800 1ah3:A (2.3) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P80276 9195881 BindingDB: IC50=16nM

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218