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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    6001 1e6z:A (1.99) BS01 NGO 3.2.1.14 GO:0004553 ... Q54276 11481469
    6002 1e6z:B (1.99) BS01 NGO 3.2.1.14 GO:0004553 ... Q54276 11481469
    6003 1e70:M (1.65) BS01 G2F 3.2.1.147 GO:0004553 ... P29736 10978344
    6004 1e70:M (1.65) BS02 ZN 3.2.1.147 GO:0004553 ... P29736 10978344
    6005 1e70:M (1.65) BS03 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6006 1e70:M (1.65) BS04 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6007 1e70:M (1.65) BS05 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6008 1e71:M (1.5) BS01 ASC 3.2.1.147 GO:0004553 ... P29736 10978344
    6009 1e71:M (1.5) BS02 ZN 3.2.1.147 GO:0004553 ... P29736 10978344
    6010 1e71:M (1.5) BS03 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6011 1e71:M (1.5) BS04 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6012 1e71:M (1.5) BS05 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6013 1e71:M (1.5) BS06 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6014 1e72:M (1.6) BS01 ASC 3.2.1.147 GO:0004553 ... P29736 10978344
    6015 1e72:M (1.6) BS02 GOX 3.2.1.147 GO:0004553 ... P29736 10978344 MOAD: Ki=0.6mM
    PDBbind: -logKd/Ki=3.22, Ki=0.6mM
    6016 1e72:M (1.6) BS03 ZN 3.2.1.147 GO:0004553 ... P29736 10978344
    6017 1e72:M (1.6) BS04 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6018 1e72:M (1.6) BS05 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6019 1e73:M (1.5) BS01 ASC 3.2.1.147 GO:0004553 ... P29736 10978344
    6020 1e73:M (1.5) BS02 G2F 3.2.1.147 GO:0004553 ... P29736 10978344
    6021 1e73:M (1.5) BS03 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6022 1e73:M (1.5) BS04 SO4 3.2.1.147 GO:0004553 ... P29736 10978344
    6023 1e73:M (1.5) BS05 ZN 3.2.1.147 GO:0004553 ... P29736 10978344
    6024 1e77:A (2.69) BS01 BG6 1.1.1.363 GO:0004345 ... P11411 11106478
    6025 1e79:A (2.4) BS01 ATP 3.6.1.34 GO:0005515 ... P19483 11062563
    6026 1e79:B (2.4) BS01 ADP 3.6.1.34 GO:0005515 ... P19483 11062563
    6027 1e79:C (2.4) BS01 ATP 3.6.1.34 GO:0005515 ... P19483 11062563
    6028 1e79:D (2.4) BS01 ADP 7.1.2.2 GO:0005515 ... P00829 11062563
    6029 1e79:D (2.4) BS02 DCW 7.1.2.2 GO:0005515 ... P00829 11062563
    6030 1e79:F (2.4) BS01 ADP 7.1.2.2 GO:0005515 ... P00829 11062563
    6031 1e7a:A (2.2) BS01 PFL ? GO:0003677 ... P02768 10940303
    6032 1e7a:A (2.2) BS02 PFL ? GO:0003677 ... P02768 10940303
    6033 1e7a:B (2.2) BS01 PFL ? GO:0003677 ... P02768 10940303
    6034 1e7a:B (2.2) BS02 PFL ? GO:0003677 ... P02768 10940303
    6035 1e7b:A (2.38) BS01 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6036 1e7b:A (2.38) BS02 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6037 1e7b:B (2.38) BS01 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6038 1e7b:B (2.38) BS02 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6039 1e7b:B (2.38) BS03 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6040 1e7c:A (2.4) BS01 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6041 1e7c:A (2.4) BS02 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6042 1e7c:A (2.4) BS03 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6043 1e7c:A (2.4) BS04 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6044 1e7c:A (2.4) BS05 HLT ? GO:0003677 ... P02768 10940303 BindingDB: IC50=2900000nM
    6045 1e7k:A (2.9) BS01 rna ? GO:0000398 ... P55769 11163207
    6046 1e7k:B (2.9) BS01 rna ? GO:0000398 ... P55769 11163207
    6047 1e7p:A (3.1) BS01 FAD 1.3.5.1 GO:0000104 ... P17412 11248702
    6048 1e7p:B (3.1) BS01 FES 1.3.5.1 GO:0005886 ... P17596 11248702
    6049 1e7p:B (3.1) BS02 F3S 1.3.5.1 GO:0005886 ... P17596 11248702
    6050 1e7p:B (3.1) BS03 SF4 1.3.5.1 GO:0005886 ... P17596 11248702
    6051 1e7p:C (3.1) BS01 HEM ? GO:0005886 ... P17413 11248702
    6052 1e7p:C (3.1) BS02 HEM ? GO:0005886 ... P17413 11248702
    6053 1e7p:D (3.1) BS01 FAD 1.3.5.1 GO:0000104 ... P17412 11248702
    6054 1e7p:E (3.1) BS01 FES 1.3.5.1 GO:0005886 ... P17596 11248702
    6055 1e7p:E (3.1) BS02 F3S 1.3.5.1 GO:0005886 ... P17596 11248702
    6056 1e7p:E (3.1) BS03 SF4 1.3.5.1 GO:0005886 ... P17596 11248702
    6057 1e7p:F (3.1) BS01 HEM ? GO:0005886 ... P17413 11248702
    6058 1e7p:F (3.1) BS02 HEM ? GO:0005886 ... P17413 11248702
    6059 1e7p:G (3.1) BS01 FAD 1.3.5.1 GO:0000104 ... P17412 11248702
    6060 1e7p:H (3.1) BS01 FES 1.3.5.1 GO:0005886 ... P17596 11248702
    6061 1e7p:H (3.1) BS02 F3S 1.3.5.1 GO:0005886 ... P17596 11248702
    6062 1e7p:H (3.1) BS03 SF4 1.3.5.1 GO:0005886 ... P17596 11248702
    6063 1e7p:I (3.1) BS01 HEM ? GO:0005886 ... P17413 11248702
    6064 1e7p:I (3.1) BS02 HEM ? GO:0005886 ... P17413 11248702
    6065 1e7p:J (3.1) BS01 FAD 1.3.5.1 GO:0000104 ... P17412 11248702
    6066 1e7p:K (3.1) BS01 FES 1.3.5.1 GO:0005886 ... P17596 11248702
    6067 1e7p:K (3.1) BS02 F3S 1.3.5.1 GO:0005886 ... P17596 11248702
    6068 1e7p:K (3.1) BS03 SF4 1.3.5.1 GO:0005886 ... P17596 11248702
    6069 1e7p:L (3.1) BS01 HEM ? GO:0005886 ... P17413 11248702
    6070 1e7p:L (3.1) BS02 HEM ? GO:0005886 ... P17413 11248702
    6071 1e7q:A (1.6) BS01 NAP 1.1.1.271 GO:0005737 ... P32055 11021971
    6072 1e7q:A (1.6) BS02 UVW 1.1.1.271 GO:0005737 ... P32055 11021971
    6073 1e7r:A (1.6) BS01 NAP 1.1.1.271 GO:0005737 ... P32055 11021971
    6074 1e7r:A (1.6) BS02 UVW 1.1.1.271 GO:0005737 ... P32055 11021971
    6075 1e7s:A (1.5) BS01 NAP 1.1.1.271 GO:0005737 ... P32055 11021971
    6076 1e7s:A (1.5) BS02 UVW 1.1.1.271 GO:0005737 ... P32055 11021971
    6077 1e7w:A (1.75) BS01 NDP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6078 1e7w:A (1.75) BS02 MTX 1.5.1.33 GO:0004155 ... Q01782 11373620 BindingDB: Ki=180nM
    6079 1e7w:B (1.75) BS01 NDP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6080 1e7w:B (1.75) BS02 MTX 1.5.1.33 GO:0004155 ... Q01782 11373620 BindingDB: Ki=180nM
    6081 1e7y:A (2.48) BS01 BG6 1.1.1.363 GO:0004345 ... P11411 11106478
    6082 1e7y:A (2.48) BS02 NDP 1.1.1.363 GO:0004345 ... P11411 11106478
    6083 1e83:A (2.05) BS01 HEC ? GO:0005506 ... P00138 11060017
    6084 1e84:A (1.9) BS01 HEC ? GO:0005506 ... P00138 11060017
    6085 1e85:A (1.35) BS01 HEC ? GO:0005506 ... P00138 11060017
    6086 1e86:A (1.95) BS01 HEC ? GO:0005506 ... P00138 11060017
    6087 1e86:A (1.95) BS02 CMO ? GO:0005506 ... P00138 11060017
    6088 1e8a:A (1.95) BS01 CA ? GO:0002548 ... P80511 11134923
    6089 1e8a:A (1.95) BS02 CA ? GO:0002548 ... P80511 11134923
    6090 1e8a:B (1.95) BS01 CA ? GO:0002548 ... P80511 11134923
    6091 1e8a:B (1.95) BS02 CA ? GO:0002548 ... P80511 11134923
    6092 1e8c:A (2.0) BS01 UAG 6.3.2.13 GO:0000287 ... P22188 11124264
    6093 1e8c:A (2.0) BS02 API 6.3.2.13 GO:0000287 ... P22188 11124264
    6094 1e8c:B (2.0) BS01 UAG 6.3.2.13 GO:0000287 ... P22188 11124264
    6095 1e8c:B (2.0) BS02 API 6.3.2.13 GO:0000287 ... P22188 11124264
    6096 1e8e:A (-1.00) BS01 HEC ? GO:0003674 ... Q9RQB9 11327772
    6097 1e8g:A (2.1) BS01 FAD 1.1.3.38 GO:0003824 ... P56216 10984479 MOAD: Kd=1.8uM
    6098 1e8g:A (2.1) BS02 FCR 1.1.3.38 GO:0003824 ... P56216 10984479
    6099 1e8g:B (2.1) BS01 FAD 1.1.3.38 GO:0003824 ... P56216 10984479 MOAD: Kd=1.8uM
    6100 1e8g:B (2.1) BS02 FCR 1.1.3.38 GO:0003824 ... P56216 10984479
    6101 1e8h:A (2.6) BS01 ADP 1.1.3.38 GO:0003824 ... P56216 10984479 PDBbind: -logKd/Ki=5.68, Kd=2.1uM
    6102 1e8h:B (2.6) BS01 ADP 1.1.3.38 GO:0003824 ... P56216 10984479
    6103 1e8k:A (1.9) BS01 ALA 5.2.1.8 GO:0000413 ... P52011 11180378
    6104 1e8k:A (1.9) BS02 PRO 5.2.1.8 GO:0000413 ... P52011 11180378
    6105 1e8m:A (1.5) BS01 P0H 3.4.21.26 GO:0004252 ... P23687 11031266
    6106 1e8n:A (1.5) BS01 peptide 3.4.21.26 GO:0004252 ... P23687 11031266
    6107 1e8o:A (3.2) BS01 rna ? GO:0003723 ... P49458 11089964
    6108 1e8o:B (3.2) BS01 rna ? GO:0005786 ... P37108 11089964
    6109 1e8o:C (3.2) BS01 rna ? GO:0003723 ... P49458 11089964
    6110 1e8o:D (3.2) BS01 rna ? GO:0005786 ... P37108 11089964
    6111 1e8t:A (2.5) BS01 CA 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6112 1e8u:A (2.0) BS01 CA 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6113 1e8u:A (2.0) BS02 SLB 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6114 1e8u:B (2.0) BS01 CA 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6115 1e8u:B (2.0) BS02 SLB 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6116 1e8v:A (2.0) BS01 CA 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6117 1e8v:A (2.0) BS02 DAN 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6118 1e8v:B (2.0) BS01 CA 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6119 1e8v:B (2.0) BS02 DAN 3.2.1.18 GO:0004308 ... Q9Q2W5 11062565
    6120 1e92:A (2.2) BS01 NAP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6121 1e92:A (2.2) BS02 HBI 1.5.1.33 GO:0004155 ... Q01782 11373620
    6122 1e92:B (2.2) BS01 NAP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6123 1e92:B (2.2) BS02 HBI 1.5.1.33 GO:0004155 ... Q01782 11373620
    6124 1e92:C (2.2) BS01 NAP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6125 1e92:C (2.2) BS02 HBI 1.5.1.33 GO:0004155 ... Q01782 11373620
    6126 1e92:D (2.2) BS01 NAP 1.5.1.33 GO:0004155 ... Q01782 11373620
    6127 1e92:D (2.2) BS02 HBI 1.5.1.33 GO:0004155 ... Q01782 11373620
    6128 1e93:A (2.0) BS01 HEM 1.11.1.6 GO:0004096 ... P42321 12486720
    6129 1e94:E (2.8) BS01 ANP ? GO:0000287 ... P0A6H5 11114186
    6130 1e94:F (2.8) BS01 ANP ? GO:0000287 ... P0A6H5 11114186
    6131 1e96:A (2.4) BS01 GTP 3.6.5.2 GO:0001764 ... P63000 11090627 MOAD: Kd=2.7uM
    6132 1e96:A (2.4) BS02 MG 3.6.5.2 GO:0001764 ... P63000 11090627
    6133 1e98:A (1.9) BS01 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6134 1e98:A (1.9) BS02 ATM 2.7.4.9 GO:0004550 ... P23919 11071809
    6135 1e99:A (1.8) BS01 ATM 2.7.4.9 GO:0004550 ... P23919 11071809
    6136 1e99:A (1.8) BS02 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6137 1e9a:A (1.6) BS01 Z5A 2.7.4.9 GO:0004550 ... P23919 11071809
    6138 1e9b:A (1.7) BS01 ATM 2.7.4.9 GO:0004550 ... P23919 11071809
    6139 1e9b:A (1.7) BS02 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6140 1e9b:A (1.7) BS03 ANP 2.7.4.9 GO:0004550 ... P23919 11071809
    6141 1e9c:A (1.6) BS01 TMP 2.7.4.9 GO:0004550 ... P23919 11071809
    6142 1e9c:A (1.6) BS02 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6143 1e9c:A (1.6) BS03 ANP 2.7.4.9 GO:0004550 ... P23919 11071809
    6144 1e9d:A (1.7) BS01 ATM 2.7.4.9 GO:0004550 ... P23919 11071809
    6145 1e9d:A (1.7) BS02 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6146 1e9e:A (1.6) BS01 TMP 2.7.4.9 GO:0004550 ... P23919 11071809
    6147 1e9e:A (1.6) BS02 ADP 2.7.4.9 GO:0004550 ... P23919 11071809
    6148 1e9g:A (1.15) BS01 MN 3.6.1.1 GO:0000287 ... P00817 11248042
    6149 1e9g:A (1.15) BS02 MN 3.6.1.1 GO:0000287 ... P00817 11248042
    6150 1e9g:A (1.15) BS03 PO4 3.6.1.1 GO:0000287 ... P00817 11248042
    6151 1e9g:A (1.15) BS04 PO4 3.6.1.1 GO:0000287 ... P00817 11248042
    6152 1e9g:B (1.15) BS01 MN 3.6.1.1 GO:0000287 ... P00817 11248042
    6153 1e9g:B (1.15) BS02 MN 3.6.1.1 GO:0000287 ... P00817 11248042
    6154 1e9g:B (1.15) BS03 PO4 3.6.1.1 GO:0000287 ... P00817 11248042
    6155 1e9g:B (1.15) BS04 PO4 3.6.1.1 GO:0000287 ... P00817 11248042
    6156 1e9h:A (2.5) BS01 INR 2.7.11.22 GO:0000082 ... P24941 11377199 MOAD: ic50=35nM
    PDBbind: -logKd/Ki=7.46, IC50=35nM
    BindingDB: IC50=3e+2nM
    6157 1e9h:C (2.5) BS01 INR 2.7.11.22 GO:0000082 ... P24941 11377199 MOAD: ic50=35nM
    BindingDB: IC50=3e+2nM
    6158 1e9i:A (2.48) BS01 MG 4.2.1.11 GO:0000015 ... P0A6P9 11676541
    6159 1e9i:B (2.48) BS01 MG 4.2.1.11 GO:0000015 ... P0A6P9 11676541
    6160 1e9i:C (2.48) BS01 MG 4.2.1.11 GO:0000015 ... P0A6P9 11676541
    6161 1e9i:D (2.48) BS01 MG 4.2.1.11 GO:0000015 ... P0A6P9 11676541
    6162 1e9l:A (2.5) BS01 GCS 3.2.1.52 GO:0000272 ... O35744 11278670
    6163 1e9o:A (1.85) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6164 1e9o:A (1.85) BS02 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6165 1e9o:B (1.85) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6166 1e9o:B (1.85) BS02 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6167 1e9p:A (1.7) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6168 1e9p:A (1.7) BS02 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6169 1e9p:B (1.7) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6170 1e9p:B (1.7) BS02 ZN 1.15.1.1 GO:0000209 ... P00442 11080458
    6171 1e9q:A (1.75) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6172 1e9q:A (1.75) BS02 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6173 1e9q:B (1.75) BS01 CU 1.15.1.1 GO:0000209 ... P00442 11080458
    6174 1e9q:B (1.75) BS02 ZN 1.15.1.1 GO:0000209 ... P00442 11080458
    6175 1e9v:A (1.79) BS01 FSO 1.7.99.1 GO:0003824 ... P31101 N/A
    6176 1e9v:A (1.79) BS02 SF4 1.7.99.1 GO:0003824 ... P31101 N/A
    6177 1e9x:A (2.1) BS01 HEM 1.14.15.36 GO:0004497 ... P9WPP9 11248033
    6178 1e9x:A (2.1) BS02 PIM 1.14.15.36 GO:0004497 ... P9WPP9 11248033
    6179 1ea1:A (2.21) BS01 HEM 1.14.15.36 GO:0004497 ... P9WPP9 11248033
    6180 1ea1:A (2.21) BS02 TPF 1.14.15.36 GO:0004497 ... P9WPP9 11248033
    6181 1ea4:A (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6182 1ea4:A (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6183 1ea4:B (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6184 1ea4:B (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6185 1ea4:B (2.95) BS03 dna ? GO:0003677 ... P13920 11428897
    6186 1ea4:D (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6187 1ea4:D (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6188 1ea4:E (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6189 1ea4:E (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6190 1ea4:F (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6191 1ea4:F (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6192 1ea4:G (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6193 1ea4:G (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6194 1ea4:H (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6195 1ea4:H (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6196 1ea4:J (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6197 1ea4:J (2.95) BS02 dna ? GO:0003677 ... P13920 11428897
    6198 1ea4:K (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6199 1ea4:L (2.95) BS01 dna ? GO:0003677 ... P13920 11428897
    6200 1ea4:L (2.95) BS02 dna ? GO:0003677 ... P13920 11428897

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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