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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    54201 2hys:A (1.2) BS01 HEM ? GO:0005576 ... Q26241 17290983
    54202 2hyu:A (1.86) BS01 SGN ? GO:0001525 ... P07355 16882661
    54203 2hyu:A (1.86) BS02 IDS ? GO:0001525 ... P07355 16882661
    54204 2hyu:A (1.86) BS03 UAP ? GO:0001525 ... P07355 16882661
    54205 2hyu:A (1.86) BS04 CA ? GO:0001525 ... P07355 16882661
    54206 2hyu:A (1.86) BS05 CA ? GO:0001525 ... P07355 16882661
    54207 2hyu:A (1.86) BS06 CA ? GO:0001525 ... P07355 16882661
    54208 2hyu:A (1.86) BS07 CA ? GO:0001525 ... P07355 16882661
    54209 2hyu:A (1.86) BS08 CA ? GO:0001525 ... P07355 16882661
    54210 2hyv:A (1.42) BS01 SGN ? GO:0001525 ... P07355 16882661
    54211 2hyv:A (1.42) BS02 IDS ? GO:0001525 ... P07355 16882661
    54212 2hyv:A (1.42) BS03 CA ? GO:0001525 ... P07355 16882661
    54213 2hyv:A (1.42) BS04 CA ? GO:0001525 ... P07355 16882661
    54214 2hyv:A (1.42) BS05 CA ? GO:0001525 ... P07355 16882661
    54215 2hyv:A (1.42) BS06 CA ? GO:0001525 ... P07355 16882661
    54216 2hyv:A (1.42) BS07 CA ? GO:0001525 ... P07355 16882661
    54217 2hyw:A (2.1) BS01 CA ? GO:0001525 ... P07355 16882661
    54218 2hyw:A (2.1) BS02 CA ? GO:0001525 ... P07355 16882661
    54219 2hyw:A (2.1) BS03 CA ? GO:0001525 ... P07355 16882661
    54220 2hyw:A (2.1) BS04 CA ? GO:0001525 ... P07355 16882661
    54221 2hyw:A (2.1) BS05 CA ? GO:0001525 ... P07355 16882661
    54222 2hyw:A (2.1) BS06 CA ? GO:0001525 ... P07355 16882661
    54223 2hyw:A (2.1) BS07 CA ? GO:0001525 ... P07355 16882661
    54224 2hyw:B (2.1) BS01 CA ? GO:0001525 ... P07355 16882661
    54225 2hyw:B (2.1) BS02 CA ? GO:0001525 ... P07355 16882661
    54226 2hyw:B (2.1) BS03 CA ? GO:0001525 ... P07355 16882661
    54227 2hyw:B (2.1) BS04 CA ? GO:0001525 ... P07355 16882661
    54228 2hyw:B (2.1) BS05 CA ? GO:0001525 ... P07355 16882661
    54229 2hyw:B (2.1) BS06 CA ? GO:0001525 ... P07355 16882661
    54230 2hyw:B (2.1) BS07 CA ? GO:0001525 ... P07355 16882661
    54231 2hz1:A (1.8) BS01 SO3 ? GO:0005344 ... P73925 17242429
    54232 2hz1:A (1.8) BS02 HEM ? GO:0005344 ... P73925 17242429
    54233 2hz2:A (2.0) BS01 HEM ? GO:0005344 ... P73925 17242429
    54234 2hz3:A (1.9) BS01 HEM ? GO:0005344 ... P73925 17242429
    54235 2hza:A (2.1) BS01 NI ? GO:0000976 ... P0A6Z6 16945905
    54236 2hza:A (2.1) BS02 3CM ? GO:0000976 ... P0A6Z6 16945905
    54237 2hza:B (2.1) BS01 3CM ? GO:0000976 ... P0A6Z6 16945905
    54238 2hza:B (2.1) BS02 NI ? GO:0000976 ... P0A6Z6 16945905
    54239 2hzh:A (2.6) BS01 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    54240 2hzh:A (2.6) BS02 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    54241 2hzh:A (2.6) BS03 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    54242 2hzh:A (2.6) BS04 CU 1.10.3.2 GO:0005507 ... Q8TG94 N/A
    54243 2hzl:A (1.4) BS01 NA ? GO:0015849 ... Q3J1R2 17362499
    54244 2hzl:A (1.4) BS02 PYR ? GO:0015849 ... Q3J1R2 17362499 MOAD: Kd=270nM
    PDBbind: -logKd/Ki=6.57, Kd=270nM
    54245 2hzl:B (1.4) BS01 NA ? GO:0015849 ... Q3J1R2 17362499
    54246 2hzl:B (1.4) BS02 PYR ? GO:0015849 ... Q3J1R2 17362499 MOAD: Kd=270nM
    54247 2hzl:B (1.4) BS03 PYR ? GO:0015849 ... Q3J1R2 17362499 MOAD: Kd=270nM
    54248 2hzp:A (2.0) BS01 PLP 3.7.1.3 GO:0005654 ... Q16719 17300176
    54249 2hzq:A (1.8) BS01 STR ? GO:0000302 ... P05090 17699160 MOAD: Kd~1uM
    54250 2hzs:B (2.7) BS01 peptide ? GO:0000979 ... P32585 16964259
    54251 2hzs:D (2.7) BS01 peptide ? GO:0000979 ... P32585 16964259
    54252 2hzs:F (2.7) BS01 peptide ? GO:0000979 ... P32585 16964259
    54253 2hzs:F (2.7) BS02 peptide ? GO:0000979 ... P32585 16964259
    54254 2hzs:H (2.7) BS01 peptide ? GO:0000979 ... P32585 16964259
    54255 2hzv:A (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54256 2hzv:A (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54257 2hzv:A (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54258 2hzv:B (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54259 2hzv:B (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54260 2hzv:B (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54261 2hzv:C (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54262 2hzv:C (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54263 2hzv:C (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54264 2hzv:D (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54265 2hzv:D (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54266 2hzv:D (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54267 2hzv:E (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54268 2hzv:E (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54269 2hzv:E (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54270 2hzv:F (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54271 2hzv:F (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54272 2hzv:F (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54273 2hzv:G (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54274 2hzv:G (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54275 2hzv:G (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54276 2hzv:H (3.1) BS01 dna ? GO:0000976 ... P0A6Z6 16945905
    54277 2hzv:H (3.1) BS02 dna ? GO:0000976 ... P0A6Z6 16945905
    54278 2hzv:H (3.1) BS03 NI ? GO:0000976 ... P0A6Z6 16945905
    54279 2i03:B (2.4) BS01 AXD 3.4.14.5 GO:0001618 ... P27487 17034148 PDBbind: -logKd/Ki=9.00, Ki=1.0nM
    54280 2i05:A (2.6) BS01 dna ? GO:0003677 ... P16525 N/A
    54281 2i05:A (2.6) BS02 dna ? GO:0003677 ... P16525 N/A
    54282 2i06:A (2.2) BS01 dna ? GO:0003677 ... P16525 N/A
    54283 2i06:A (2.2) BS02 dna ? GO:0003677 ... P16525 N/A
    54284 2i0b:A (1.96) BS01 GLU ? GO:0015276 ... P42260 17115050
    54285 2i0b:B (1.96) BS01 GLU ? GO:0015276 ... P42260 17115050
    54286 2i0b:C (1.96) BS01 GLU ? GO:0015276 ... P42260 17115050
    54287 2i0c:A (2.25) BS01 GLU ? GO:0015276 ... P42260 17115050
    54288 2i0c:B (2.25) BS01 GLU ? GO:0015276 ... P42260 17115050
    54289 2i0h:A (2.0) BS01 222 2.7.11.24 GO:0000077 ... Q16539 16945533 MOAD: ic50=9nM
    PDBbind: -logKd/Ki=8.05, IC50=9nM
    54290 2i0h:A (2.0) BS02 222 2.7.11.24 GO:0000077 ... Q16539 16945533 MOAD: ic50=9nM
    PDBbind: -logKd/Ki=8.05, IC50=9nM
    54291 2i0m:A (2.4) BS01 ZN ? GO:0005737 ... P0A3Y7 N/A
    54292 2i0m:A (2.4) BS02 ZN ? GO:0005737 ... P0A3Y7 N/A
    54293 2i0q:A (1.91) BS01 dna ? GO:0000723 ... P29549 17082188
    54294 2i0q:B (1.91) BS01 dna ? GO:0000781 ... P16458 17082188
    54295 2i0s:D (1.4) BS01 HY1 1.4.9.2 GO:0009308 ... P84887 17475620
    54296 2i0s:H (1.4) BS01 HY1 1.4.9.2 GO:0009308 ... P84887 17475620
    54297 2i0t:D (1.35) BS01 PEL 1.4.9.2 GO:0009308 ... P84887 17475620
    54298 2i0t:H (1.35) BS01 PEL 1.4.9.2 GO:0009308 ... P84887 17475620
    54299 2i0u:A (2.2) BS01 CA 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54300 2i0u:A (2.2) BS02 TRT 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54301 2i0u:A (2.2) BS03 TFA 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54302 2i0u:E (2.2) BS01 CA 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54303 2i0u:E (2.2) BS02 TRT 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54304 2i0u:E (2.2) BS03 TFA 3.1.1.4 GO:0004623 ... Q1RP79 N/A
    54305 2i16:A (0.81) BS01 NDP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 17139089
    54306 2i16:A (0.81) BS02 LDT 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 17139089 BindingDB: IC50=30nM
    54307 2i17:A (0.81) BS01 NDP 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 17139089
    54308 2i17:A (0.81) BS02 LDT 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54
    GO:0001523 ... P15121 17139089 BindingDB: IC50=30nM
    54309 2i19:A (2.28) BS01 MG 2.5.1.10 GO:0004161 ... Q86C09 17090032
    54310 2i19:A (2.28) BS02 MG 2.5.1.10 GO:0004161 ... Q86C09 17090032
    54311 2i19:A (2.28) BS03 1BY 2.5.1.10 GO:0004161 ... Q86C09 17090032 PDBbind: -logKd/Ki=7.80, Ki=16nM
    54312 2i19:B (2.28) BS01 MG 2.5.1.10 GO:0004161 ... Q86C09 17090032
    54313 2i19:B (2.28) BS02 MG 2.5.1.10 GO:0004161 ... Q86C09 17090032
    54314 2i19:B (2.28) BS03 1BY 2.5.1.10 GO:0004161 ... Q86C09 17090032 PDBbind: -logKd/Ki=7.80, Ki=16nM
    54315 2i1v:B (2.5) BS01 FDP 2.7.1.105
    3.1.3.46
    GO:0003824 ... Q16875 17499765
    54316 2i1v:B (2.5) BS02 F6P 2.7.1.105
    3.1.3.46
    GO:0003824 ... Q16875 17499765
    54317 2i1v:B (2.5) BS03 ADP 2.7.1.105
    3.1.3.46
    GO:0003824 ... Q16875 17499765
    54318 2i1v:B (2.5) BS04 PHS 2.7.1.105
    3.1.3.46
    GO:0003824 ... Q16875 17499765
    54319 2i1x:A (2.0) BS01 RET ? GO:0005216 ... P02945 17002299
    54320 2i20:A (2.08) BS01 RET ? GO:0005216 ... P02945 17002299
    54321 2i21:A (1.84) BS01 RET ? GO:0005216 ... P02945 17002299
    54322 2i22:B (2.8) BS01 I22 5.3.1.28 GO:0005737 ... P63224 18056714
    54323 2i22:C (2.8) BS01 I22 5.3.1.28 GO:0005737 ... P63224 18056714
    54324 2i29:A (2.1) BS01 NAD 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54325 2i2a:A (2.1) BS01 NAP 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780 MOAD: Ki=0.04mM
    54326 2i2a:A (2.1) BS02 GOL 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54327 2i2b:A (2.1) BS01 CC5 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780 PDBbind: -logKd/Ki=2.44, Ki=3.6mM
    54328 2i2b:A (2.1) BS02 CC5 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780 PDBbind: -logKd/Ki=2.44, Ki=3.6mM
    54329 2i2b:A (2.1) BS03 GOL 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54330 2i2c:A (1.85) BS01 DTA 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780 MOAD: Ki=0.02mM
    PDBbind: -logKd/Ki=4.70, Ki=0.02mM
    54331 2i2d:A (2.22) BS01 A2D 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54332 2i2f:A (1.9) BS01 NAD 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54333 2i2f:A (1.9) BS02 GOL 2.7.1.23 GO:0003951 ... Q8Y8D7 17686780
    54334 2i2r:A (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54335 2i2r:B (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54336 2i2r:C (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54337 2i2r:D (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54338 2i2r:I (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54339 2i2r:J (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54340 2i2r:K (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54341 2i2r:L (3.35) BS01 ZN ? GO:0005249 ... Q62897 17057713
    54342 2i2s:A (2.3) BS01 MNA ? GO:0019028 ... P0C6Y8 17306299
    54343 2i2s:A (2.3) BS02 MNA ? GO:0019028 ... P0C6Y8 17306299
    54344 2i2s:B (2.3) BS01 MNA ? GO:0019028 ... P0C6Y8 17306299
    54345 2i2s:B (2.3) BS02 MNA ? GO:0019028 ... P0C6Y8 17306299
    54346 2i2x:B (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54347 2i2x:D (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54348 2i2x:F (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54349 2i2x:H (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54350 2i2x:J (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54351 2i2x:L (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54352 2i2x:N (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54353 2i2x:P (2.5) BS01 B13 2.1.1.90 GO:0005515 ... Q46EH4 17142327
    54354 2i2y:A (-1.00) BS01 rna ? GO:0003676 ... P19909
    P84103
    17036044
    54355 2i30:A (2.9) BS01 SAL ? GO:0003677 ... P02768 17067818 BindingDB: Ki=5888436553556nM
    54356 2i32:A (2.7) BS01 peptide ? GO:0005634 ... Q9Y294 16980972
    54357 2i32:A (2.7) BS02 peptide ? GO:0005634 ... Q9Y294 16980972
    54358 2i32:B (2.7) BS01 peptide ? GO:0005634 ... Q9Y294 16980972
    54359 2i33:A (1.57) BS01 MG 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54360 2i33:B (1.57) BS01 MG 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54361 2i34:A (2.0) BS01 MG 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54362 2i34:A (2.0) BS02 WO4 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54363 2i34:B (2.0) BS01 MG 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54364 2i34:B (2.0) BS02 WO4 3.1.3.2 GO:0009279 ... A0A6L7HE29 N/A
    54365 2i35:A (3.8) BS01 RET ? GO:0000139 ... P02699 17060607
    54366 2i3c:A (2.8) BS01 ZN 3.5.1.15 GO:0005515 ... P45381 17194761
    54367 2i3c:B (2.8) BS01 ZN 3.5.1.15 GO:0005515 ... P45381 17194761
    54368 2i3g:A (1.85) BS01 NAP 1.2.1.38 GO:0003942 ... P9WPZ9 17316682
    54369 2i3g:B (1.85) BS01 NAP 1.2.1.38 GO:0003942 ... P9WPZ9 17316682
    54370 2i3p:A (2.3) BS01 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54371 2i3p:A (2.3) BS02 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54372 2i3p:B (2.3) BS01 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54373 2i3p:B (2.3) BS02 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54374 2i3q:A (2.3) BS01 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54375 2i3q:A (2.3) BS02 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54376 2i3q:B (2.3) BS01 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54377 2i3q:B (2.3) BS02 dna 3.1.-.- GO:0004519 ... P05725 16971456
    54378 2i3v:A (2.4) BS01 ZN ? GO:0015276 ... P19491 17018279
    54379 2i3v:A (2.4) BS02 GLU ? GO:0015276 ... P19491 17018279 PDBbind: -logKd/Ki=6.55, Ki=282nM
    54380 2i3v:B (2.4) BS01 GLU ? GO:0015276 ... P19491 17018279
    54381 2i3v:C (2.4) BS01 ZN ? GO:0015276 ... P19491 17018279
    54382 2i3v:C (2.4) BS02 GLU ? GO:0015276 ... P19491 17018279
    54383 2i3v:D (2.4) BS01 GLU ? GO:0015276 ... P19491 17018279
    54384 2i3w:A (2.3) BS01 GLU ? GO:0015276 ... P19491 17018279
    54385 2i3w:B (2.3) BS01 GLU ? GO:0015276 ... P19491 17018279
    54386 2i3z:A (2.9) BS01 LIR 3.4.14.5 GO:0001618 ... P14740 17010607 PDBbind: -logKd/Ki=8.70, Ki=2nM
    54387 2i40:A (2.8) BS01 BLZ 2.7.11.22 GO:0000082 ... P24941 16997559 PDBbind: -logKd/Ki=5.80, IC50=1.58uM
    54388 2i40:C (2.8) BS01 BLZ 2.7.11.22 GO:0000082 ... P24941 16997559
    54389 2i4j:A (2.1) BS01 DRJ ? GO:0003677 ... P37231 17403688 PDBbind: -logKd/Ki=6.16, Kd=684.8nM
    BindingDB: Ki=88nM, Kd=270nM, EC50=73.3nM
    54390 2i4m:B (2.8) BS01 P5A 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54391 2i4m:C (2.8) BS01 P5A 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54392 2i4n:A (2.85) BS01 5CA 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54393 2i4n:B (2.85) BS01 5CA 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54394 2i4n:C (2.85) BS01 5CA 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54395 2i4o:A (2.4) BS01 MG 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54396 2i4o:A (2.4) BS02 ATP 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54397 2i4o:B (2.4) BS01 MG 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54398 2i4o:B (2.4) BS02 ATP 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54399 2i4o:C (2.4) BS01 MG 6.1.1.15 GO:0000166 ... Q6N5P6 17027500
    54400 2i4o:C (2.4) BS02 ATP 6.1.1.15 GO:0000166 ... Q6N5P6 17027500

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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