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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    50601 2f3z:A (1.6) BS02 CA ? GO:0000086 ... P0DP23 16338416
    50602 2f3z:A (1.6) BS03 CA ? GO:0000086 ... P0DP23 16338416
    50603 2f3z:A (1.6) BS04 CA ? GO:0000086 ... P0DP23 16338416
    50604 2f3z:A (1.6) BS05 CA ? GO:0000086 ... P0DP23 16338416
    50605 2f43:A (3.0) BS01 ATP 3.6.3.14 GO:0001937 ... P15999 16531409
    50606 2f43:B (3.0) BS01 VO4 7.1.2.2 GO:0001525 ... P10719 16531409
    50607 2f43:B (3.0) BS02 MG 7.1.2.2 GO:0001525 ... P10719 16531409
    50608 2f43:B (3.0) BS03 ADP 7.1.2.2 GO:0001525 ... P10719 16531409
    50609 2f48:A (2.11) BS01 FBP 2.7.1.90 GO:0003872 ... P70826 N/A
    50610 2f48:B (2.11) BS01 FBP 2.7.1.90 GO:0003872 ... P70826 N/A
    50611 2f48:B (2.11) BS02 AF3 2.7.1.90 GO:0003872 ... P70826 N/A
    50612 2f49:A (1.9) BS01 peptide 2.7.11.24 GO:0000749 ... P16892 16424299
    50613 2f49:A (1.9) BS02 MG 2.7.11.24 GO:0000749 ... P16892 16424299
    50614 2f49:B (1.9) BS01 MG 2.7.11.24 GO:0000749 ... P16892 16424299
    50615 2f4a:A (1.95) BS01 TOU 3.2.1.17 GO:0003796 ... P00698 16600702
    50616 2f4a:A (1.95) BS02 TOU 3.2.1.17 GO:0003796 ... P00698 16600702
    50617 2f4b:A (2.07) BS01 EHA ? GO:0003677 ... P37231 16451087 MOAD: ic50=50nM
    PDBbind: -logKd/Ki=7.30, IC50=0.05uM
    BindingDB: IC50=50nM, EC50=70nM
    50618 2f4g:A (1.654) BS01 BRJ 3.2.1.17 GO:0003796 ... P00698 16600702
    50619 2f4v:B (3.8) BS01 rna ? GO:0003735 ... P80371 16492561 PDBbind: Kd=2.2uM
    50620 2f4v:C (3.8) BS01 rna ? GO:0003676 ... P80372 16492561 PDBbind: Kd=2.2uM
    50621 2f4v:D (3.8) BS01 rna ? GO:0003723 ... P80373 16492561 PDBbind: Kd=2.2uM
    50622 2f4v:D (3.8) BS02 ZN ? GO:0003723 ... P80373 16492561
    50623 2f4v:D (3.8) BS03 MG ? GO:0003723 ... P80373 16492561
    50624 2f4v:E (3.8) BS01 rna ? GO:0003723 ... Q5SHQ5 16492561 PDBbind: Kd=2.2uM
    50625 2f4v:F (3.8) BS01 rna ? GO:0003735 ... Q5SLP8 16492561 PDBbind: Kd=2.2uM
    50626 2f4v:G (3.8) BS01 rna ? GO:0000028 ... P17291 16492561 PDBbind: Kd=2.2uM
    50627 2f4v:H (3.8) BS01 rna ? GO:0003735 ... P0DOY9 16492561 PDBbind: Kd=2.2uM
    50628 2f4v:I (3.8) BS01 rna ? GO:0000049 ... P80374 16492561 PDBbind: Kd=2.2uM
    50629 2f4v:J (3.8) BS01 rna ? GO:0000049 ... Q5SHN7 16492561 PDBbind: Kd=2.2uM
    50630 2f4v:K (3.8) BS01 rna ? GO:0003735 ... P80376 16492561 PDBbind: Kd=2.2uM
    50631 2f4v:L (3.8) BS01 rna ? GO:0000049 ... Q5SHN3 16492561 PDBbind: Kd=2.2uM
    50632 2f4v:M (3.8) BS01 rna ? GO:0000049 ... P80377 16492561 PDBbind: Kd=2.2uM
    50633 2f4v:N (3.8) BS01 rna ? GO:0003735 ... P0DOY6 16492561 PDBbind: Kd=2.2uM
    50634 2f4v:N (3.8) BS02 ZN ? GO:0003735 ... P0DOY6 16492561
    50635 2f4v:O (3.8) BS01 rna ? GO:0003735 ... Q5SJ76 16492561 PDBbind: Kd=2.2uM
    50636 2f4v:P (3.8) BS01 rna ? GO:0003735 ... Q5SJH3 16492561 PDBbind: Kd=2.2uM
    50637 2f4v:Q (3.8) BS01 rna ? GO:0003735 ... P0DOY7 16492561 PDBbind: Kd=2.2uM
    50638 2f4v:R (3.8) BS01 rna ? GO:0003735 ... Q5SLQ0 16492561 PDBbind: Kd=2.2uM
    50639 2f4v:S (3.8) BS01 rna ? GO:0000028 ... Q5SHP2 16492561 PDBbind: Kd=2.2uM
    50640 2f4v:T (3.8) BS01 rna ? GO:0003723 ... P80380 16492561 PDBbind: Kd=2.2uM
    50641 2f58:L (2.8) BS01 peptide ? GO:0002250 ... P01666 10368281
    50642 2f59:A (2.3) BS01 CA 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50643 2f59:A (2.3) BS02 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50644 2f59:A (2.3) BS03 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50645 2f59:B (2.3) BS01 CA 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50646 2f59:B (2.3) BS02 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50647 2f59:B (2.3) BS03 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50648 2f59:C (2.3) BS01 CA 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50649 2f59:C (2.3) BS02 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50650 2f59:C (2.3) BS03 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50651 2f59:D (2.3) BS01 CA 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50652 2f59:D (2.3) BS02 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50653 2f59:D (2.3) BS03 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50654 2f59:E (2.3) BS01 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50655 2f59:E (2.3) BS02 INI 2.5.1.78 GO:0000906 ... Q57DY1 17854827
    50656 2f5c:A (2.4) BS01 MN ? GO:0003677 ... P54512 16533030
    50657 2f5c:A (2.4) BS02 MN ? GO:0003677 ... P54512 16533030
    50658 2f5d:A (1.9) BS01 MN ? GO:0003677 ... P54512 16533030
    50659 2f5d:A (1.9) BS02 MN ? GO:0003677 ... P54512 16533030
    50660 2f5d:B (1.9) BS01 MN ? GO:0003677 ... P54512 16533030
    50661 2f5d:B (1.9) BS02 MN ? GO:0003677 ... P54512 16533030
    50662 2f5e:A (2.2) BS01 MN ? GO:0003677 ... P54512 16533030
    50663 2f5e:A (2.2) BS02 MN ? GO:0003677 ... P54512 16533030
    50664 2f5e:B (2.2) BS01 MN ? GO:0003677 ... P54512 16533030
    50665 2f5e:B (2.2) BS02 MN ? GO:0003677 ... P54512 16533030
    50666 2f5f:A (2.4) BS01 MN ? GO:0003677 ... P54512 16533030
    50667 2f5f:A (2.4) BS02 MN ? GO:0003677 ... P54512 16533030
    50668 2f5f:B (2.4) BS01 MN ? GO:0003677 ... P54512 16533030
    50669 2f5f:B (2.4) BS02 MN ? GO:0003677 ... P54512 16533030
    50670 2f5v:A (1.41) BS01 KBG 1.1.3.10 GO:0016491 ... Q8J136 16716069
    50671 2f5v:A (1.41) BS02 FAD 1.1.3.10 GO:0016491 ... Q8J136 16716069
    50672 2f5z:A (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50673 2f5z:B (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50674 2f5z:C (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50675 2f5z:D (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50676 2f5z:E (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50677 2f5z:F (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50678 2f5z:G (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50679 2f5z:H (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50680 2f5z:I (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50681 2f5z:J (2.18) BS01 FAD 1.8.1.4 GO:0001669 ... P09622 16442803
    50682 2f62:A (1.5) BS01 12M 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50683 2f62:A (1.5) BS02 12M 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50684 2f62:B (1.5) BS01 12M 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50685 2f62:B (1.5) BS02 12M 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50686 2f64:A (1.6) BS01 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50687 2f64:A (1.6) BS02 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50688 2f64:B (1.6) BS01 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50689 2f64:B (1.6) BS02 12Q 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50690 2f67:A (1.6) BS01 12B 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50691 2f67:A (1.6) BS02 12B 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50692 2f67:B (1.6) BS01 12B 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50693 2f67:B (1.6) BS02 12B 2.4.2.6 GO:0005634 ... Q57VC7 17004709
    50694 2f69:A (1.3) BS01 peptide 2.1.1.364 GO:0005694 ... Q8WTS6 16415881
    50695 2f69:A (1.3) BS02 SAH 2.1.1.364 GO:0005694 ... Q8WTS6 16415881
    50696 2f6c:A (1.84) BS01 FAD 1.1.3.10 GO:0016491 ... Q8J136 16716069
    50697 2f6d:A (1.6) BS01 GLC 3.2.1.3 GO:0000272 ... P08017 16649993
    50698 2f6d:A (1.6) BS02 GLC 3.2.1.3 GO:0000272 ... P08017 16649993
    50699 2f6d:A (1.6) BS03 AC1 3.2.1.3 GO:0000272 ... P08017 16649993
    50700 2f6d:A (1.6) BS04 GLC 3.2.1.3 GO:0000272 ... P08017 16649993
    50701 2f6d:A (1.6) BS05 AC1 3.2.1.3 GO:0000272 ... P08017 16649993
    50702 2f6j:A (2.0) BS01 peptide ? GO:0006357 ... Q12830 16728978
    50703 2f6j:A (2.0) BS02 ZN ? GO:0006357 ... Q12830 16728978
    50704 2f6j:A (2.0) BS03 ZN ? GO:0006357 ... Q12830 16728978
    50705 2f6j:B (2.0) BS01 ZN ? GO:0006357 ... Q12830 16728978
    50706 2f6j:B (2.0) BS02 ZN ? GO:0006357 ... Q12830 16728978
    50707 2f6j:C (2.0) BS01 ZN ? GO:0006357 ... Q12830 16728978
    50708 2f6j:C (2.0) BS02 ZN ? GO:0006357 ... Q12830 16728978
    50709 2f6k:A (2.5) BS01 MN 4.1.1.52 GO:0005737 ... F9US96 N/A
    50710 2f6k:B (2.5) BS01 MN 4.1.1.52 GO:0005737 ... F9US96 N/A
    50711 2f6n:A (2.0) BS01 ZN ? GO:0006357 ... Q12830 16728978
    50712 2f6n:A (2.0) BS02 ZN ? GO:0006357 ... Q12830 16728978
    50713 2f6n:B (2.0) BS01 ZN ? GO:0006357 ... Q12830 16728978
    50714 2f6n:B (2.0) BS02 ZN ? GO:0006357 ... Q12830 16728978
    50715 2f6x:A (2.0) BS01 1GP 2.5.1.41 GO:0000287 ... O29844 16377641
    50716 2f6x:B (2.0) BS01 1GP 2.5.1.41 GO:0000287 ... O29844 16377641
    50717 2f7e:E (2.0) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 16413780
    50718 2f7e:E (2.0) BS02 2EA 2.7.11.11 GO:0001669 ... P00517 16413780 MOAD: ic50=1.3nM
    50719 2f7f:A (2.0) BS01 NIO 6.3.4.21 GO:0004516 ... Q830Y8 N/A
    50720 2f7f:A (2.0) BS02 NIO 6.3.4.21 GO:0004516 ... Q830Y8 N/A
    50721 2f7i:A (1.6) BS01 26C ? GO:0005179 ... P02766 14711308 BindingDB: Kd=72.5nM
    50722 2f7i:B (1.6) BS01 26C ? GO:0005179 ... P02766 14711308 BindingDB: Kd=72.5nM
    50723 2f7n:A (2.0) BS01 CO 1.16.-.- GO:0003677 ... Q9RS64 16828801
    50724 2f7n:A (2.0) BS02 CO 1.16.-.- GO:0003677 ... Q9RS64 16828801
    50725 2f7o:A (1.43) BS01 ZN 3.2.1.114 GO:0000139 ... Q24451 16787095
    50726 2f7o:A (1.43) BS02 MSN 3.2.1.114 GO:0000139 ... Q24451 16787095 MOAD: Ki=0.036uM
    PDBbind: -logKd/Ki=7.44, Ki=0.036uM
    BindingDB: Ki=36nM
    50727 2f7p:A (1.28) BS01 ZN 3.2.1.114 GO:0000139 ... Q24451 16787095
    50728 2f7p:A (1.28) BS02 2SK 3.2.1.114 GO:0000139 ... Q24451 16787095 MOAD: Ki=0.249uM
    PDBbind: -logKd/Ki=6.60, Ki=0.249uM
    50729 2f7q:A (1.85) BS01 ZN 3.2.1.114 GO:0000139 ... Q24451 N/A
    50730 2f7q:A (1.85) BS02 AOL 3.2.1.114 GO:0000139 ... Q24451 N/A BindingDB: IC50=1.00e+5nM
    50731 2f7r:A (1.35) BS01 ZN 3.2.1.114 GO:0000139 ... Q24451 N/A
    50732 2f7r:A (1.35) BS02 SK3 3.2.1.114 GO:0000139 ... Q24451 N/A
    50733 2f7s:A (2.7) BS01 GDP 3.6.5.2 GO:0003924 ... O00194 N/A
    50734 2f7s:B (2.7) BS01 GDP 3.6.5.2 GO:0003924 ... O00194 N/A
    50735 2f7x:E (1.9) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 16403626
    50736 2f7x:E (1.9) BS02 4EA 2.7.11.11 GO:0001669 ... P00517 16403626 MOAD: ic50=14nM
    BindingDB: IC50=38nM
    50737 2f7z:E (3.0) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 16413780
    50738 2f7z:E (3.0) BS02 6EA 2.7.11.11 GO:0001669 ... P00517 16413780
    50739 2f8i:A (1.541) BS01 205 ? GO:0005179 ... P02766 12820260 PDBbind: -logKd/Ki=7.26, Kd=55nM
    50740 2f8i:B (1.541) BS01 205 ? GO:0005179 ... P02766 12820260 PDBbind: -logKd/Ki=7.26, Kd=55nM
    50741 2f8n:A (2.9) BS01 dna ? GO:0000786 ... P84233 N/A
    50742 2f8n:A (2.9) BS02 dna ? GO:0000786 ... P84233 N/A
    50743 2f8n:B (2.9) BS01 dna ? GO:0000786 ... P62799 N/A
    50744 2f8n:B (2.9) BS02 dna ? GO:0000786 ... P62799 N/A
    50745 2f8n:D (2.9) BS01 dna ? GO:0000786 ... Q9D2U9 N/A
    50746 2f8n:D (2.9) BS02 dna ? GO:0000786 ... Q9D2U9 N/A
    50747 2f8n:E (2.9) BS01 dna ? GO:0000786 ... P84233 N/A
    50748 2f8n:E (2.9) BS02 dna ? GO:0000786 ... P84233 N/A
    50749 2f8n:F (2.9) BS01 dna ? GO:0000786 ... P62799 N/A
    50750 2f8n:F (2.9) BS02 dna ? GO:0000786 ... P62799 N/A
    50751 2f8n:G (2.9) BS01 dna ? GO:0000786 ... O75367 N/A
    50752 2f8n:G (2.9) BS02 dna ? GO:0000786 ... O75367 N/A
    50753 2f8n:H (2.9) BS01 dna ? GO:0000786 ... P02281 N/A
    50754 2f8n:H (2.9) BS02 dna ? GO:0000786 ... P02281 N/A
    50755 2f8n:K (2.9) BS01 dna ? GO:0000786 ... Q8CGP6 N/A
    50756 2f8n:K (2.9) BS02 dna ? GO:0000786 ... Q8CGP6 N/A
    50757 2f8x:C (3.25) BS01 dna ? GO:0000978 ... Q06330 16530044
    50758 2f8x:C (3.25) BS02 dna ? GO:0000978 ... Q06330 16530044
    50759 2f90:A (2.0) BS01 ALF 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 17052986
    50760 2f90:B (2.0) BS01 ALF 5.4.2.11
    5.4.2.4
    GO:0003824 ... P07738 17052986
    50761 2f93:A (2.0) BS01 RET ? GO:0005216 ... P42196 16452929
    50762 2f95:A (2.2) BS01 RET ? GO:0005216 ... P42196 16452929
    50763 2f9g:A (2.1) BS01 MG 2.7.11.24 GO:0000749 ... P16892 16424299
    50764 2f9g:A (2.1) BS02 ADP 2.7.11.24 GO:0000749 ... P16892 16424299
    50765 2f9i:B (1.98) BS01 ZN 2.1.3.15 GO:0003989 ... Q5HF73 16460018
    50766 2f9i:D (1.98) BS01 ZN 2.1.3.15 GO:0003989 ... Q5HF73 16460018
    50767 2f9j:B (3.0) BS01 peptide ? GO:0000398 ... Q9Y3B4 16432215
    50768 2f9l:A (1.55) BS01 GDP 3.6.5.2 GO:0001881 ... Q15907 16545962
    50769 2f9m:A (1.95) BS01 MG 3.6.5.2 GO:0001881 ... Q15907 16545962
    50770 2f9m:A (1.95) BS02 GNP 3.6.5.2 GO:0001881 ... Q15907 16545962
    50771 2f9n:A (1.6) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50772 2f9n:A (1.6) BS02 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50773 2f9n:B (1.6) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50774 2f9n:B (1.6) BS02 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50775 2f9n:B (1.6) BS03 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50776 2f9n:C (1.6) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50777 2f9n:C (1.6) BS02 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50778 2f9n:D (1.6) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50779 2f9n:D (1.6) BS02 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50780 2f9n:D (1.6) BS03 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50781 2f9p:A (2.3) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50782 2f9p:A (2.3) BS02 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50783 2f9p:B (2.3) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50784 2f9p:B (2.3) BS02 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50785 2f9p:B (2.3) BS03 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50786 2f9p:C (2.3) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50787 2f9p:C (2.3) BS02 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50788 2f9p:D (2.3) BS01 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50789 2f9p:D (2.3) BS02 peptide 3.4.21.59 GO:0004252 ... Q15661 16414069
    50790 2f9p:D (2.3) BS03 BU3 3.4.21.59 GO:0004252 ... Q15661 16414069
    50791 2f9q:A (3.002) BS01 HEM 1.14.14.- GO:0004497 ... P10635 16352597
    50792 2f9q:B (3.002) BS01 HEM 1.14.14.- GO:0004497 ... P10635 16352597
    50793 2f9q:C (3.002) BS01 HEM 1.14.14.- GO:0004497 ... P10635 16352597
    50794 2f9q:D (3.002) BS01 HEM 1.14.14.- GO:0004497 ... P10635 16352597
    50795 2f9r:A (1.85) BS01 MG 4.6.1.- GO:0005576 ... Q8I914 15654080
    50796 2f9r:B (1.85) BS01 MG 4.6.1.- GO:0005576 ... Q8I914 15654080
    50797 2f9r:C (1.85) BS01 MG 4.6.1.- GO:0005576 ... Q8I914 15654080
    50798 2f9r:D (1.85) BS01 MG 4.6.1.- GO:0005576 ... Q8I914 15654080
    50799 2f9u:A (2.6) BS01 peptide 3.6.4.13 GO:0006508 ... Q91RS4 16413182
    50800 2f9u:A (2.6) BS02 peptide 3.6.4.13 GO:0006508 ... Q91RS4 16413182

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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