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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    48201 2cvw:A (2.4) BS01 TTP 1.17.4.1 GO:0000166 ... P21524 16537479
    48202 2cvw:A (2.4) BS02 GDP 1.17.4.1 GO:0000166 ... P21524 16537479
    48203 2cvx:A (2.2) BS01 DGT 1.17.4.1 GO:0000166 ... P21524 16537479
    48204 2cvx:A (2.2) BS02 ADP 1.17.4.1 GO:0000166 ... P21524 16537479
    48205 2cvy:A (2.4) BS01 peptide 1.17.4.1 GO:0000166 ... P21524 16537479
    48206 2cvy:A (2.4) BS02 TTP 1.17.4.1 GO:0000166 ... P21524 16537479
    48207 2cw0:D (3.3) BS01 ZN 2.7.7.6 GO:0000287 ... Q8RQE8 16122422
    48208 2cw0:D (3.3) BS02 ZN 2.7.7.6 GO:0000287 ... Q8RQE8 16122422
    48209 2cw0:N (3.3) BS01 ZN 2.7.7.6 GO:0000287 ... Q8RQE8 16122422
    48210 2cw0:N (3.3) BS02 MG 2.7.7.6 GO:0000287 ... Q8RQE8 16122422
    48211 2cw3:A (2.5) BS01 FE 1.15.1.1 GO:0004784 ... Q8ISI9 17077482
    48212 2cw3:B (2.5) BS01 FE 1.15.1.1 GO:0004784 ... Q8ISI9 17077482
    48213 2cw6:A (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48214 2cw6:A (2.1) BS02 3HG 4.1.3.4 GO:0000287 ... P35914 16330550
    48215 2cw6:B (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48216 2cw6:C (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48217 2cw6:D (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48218 2cw6:E (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48219 2cw6:F (2.1) BS01 MG 4.1.3.4 GO:0000287 ... P35914 16330550
    48220 2cww:A (2.6) BS01 SAH 2.1.1.191 GO:0003723 ... Q5SIT4 16511182
    48221 2cww:B (2.6) BS01 SAH 2.1.1.191 GO:0003723 ... Q5SIT4 16511182
    48222 2cx8:A (2.53) BS01 SAH 2.1.1.193 GO:0005737 ... Q5SKI6 N/A
    48223 2cx8:B (2.53) BS01 SAH 2.1.1.193 GO:0005737 ... Q5SKI6 N/A
    48224 2cxb:A (1.95) BS01 HEC ? GO:0009055 ... P0C0X8 15299423
    48225 2cxb:B (1.95) BS01 HEC ? GO:0009055 ... P0C0X8 15299423
    48226 2cxg:A (2.5) BS01 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48227 2cxg:A (2.5) BS02 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48228 2cxg:A (2.5) BS03 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48229 2cxg:A (2.5) BS04 G6D 2.4.1.19 GO:0003824 ... P43379 7857935
    48230 2cxg:A (2.5) BS05 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48231 2cxg:A (2.5) BS06 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48232 2cxg:A (2.5) BS07 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48233 2cxg:A (2.5) BS08 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48234 2cxg:A (2.5) BS09 ACI 2.4.1.19 GO:0003824 ... P43379 7857935
    48235 2cxg:A (2.5) BS10 GLC 2.4.1.19 GO:0003824 ... P43379 7857935
    48236 2cxg:A (2.5) BS11 CA 2.4.1.19 GO:0003824 ... P43379 7857935
    48237 2cxg:A (2.5) BS12 CA 2.4.1.19 GO:0003824 ... P43379 7857935
    48238 2cxn:A (1.4) BS01 PO4 5.3.1.9 GO:0001701 ... P06745 16375918
    48239 2cxo:A (1.8) BS01 DER 5.3.1.9 GO:0001701 ... P06745 16375918
    48240 2cxo:B (1.8) BS01 DER 5.3.1.9 GO:0001701 ... P06745 16375918
    48241 2cxp:A (1.7) BS01 A5P 5.3.1.9 GO:0001701 ... P06745 16375918
    48242 2cxp:B (1.7) BS01 A5P 5.3.1.9 GO:0001701 ... P06745 16375918
    48243 2cxq:A (1.5) BS01 S6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48244 2cxq:B (1.5) BS01 S6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48245 2cxr:A (1.7) BS01 6PG 5.3.1.9 GO:0001701 ... P06745 16375918
    48246 2cxr:B (1.7) BS01 6PG 5.3.1.9 GO:0001701 ... P06745 16375918
    48247 2cxs:A (1.5) BS01 F6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48248 2cxs:B (1.5) BS01 F6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48249 2cxt:A (1.5) BS01 F6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48250 2cxt:B (1.5) BS01 F6P 5.3.1.9 GO:0001701 ... P06745 16375918
    48251 2cxu:A (1.65) BS01 PO4 5.3.1.9 GO:0001701 ... P06745 16375918
    48252 2cy0:A (1.9) BS01 NAP 1.1.1.25 GO:0004764 ... Q5SJF8 17825835
    48253 2cy3:A (1.7) BS01 HEC ? GO:0009055 ... P00136 7966289
    48254 2cy3:A (1.7) BS02 HEC ? GO:0009055 ... P00136 7966289
    48255 2cy3:A (1.7) BS03 HEC ? GO:0009055 ... P00136 7966289
    48256 2cy3:A (1.7) BS04 HEC ? GO:0009055 ... P00136 7966289
    48257 2cyb:A (1.8) BS01 TYR 6.1.1.1 GO:0000166 ... O29482 16325203
    48258 2cyb:B (1.8) BS01 TYR 6.1.1.1 GO:0000166 ... O29482 16325203
    48259 2cyc:A (2.2) BS01 TYR 6.1.1.1 GO:0000166 ... O58739 16325203
    48260 2cyc:B (2.2) BS01 TYR 6.1.1.1 GO:0000166 ... O58739 16325203
    48261 2cyh:A (1.64) BS01 ALA 5.2.1.8 GO:0000413 ... P62937 8652512
    48262 2cyh:A (1.64) BS02 PRO 5.2.1.8 GO:0000413 ... P62937 8652512
    48263 2cym:A (2.0) BS01 HEM ? GO:0009055 ... P00131 1663945
    48264 2cym:A (2.0) BS02 HEM ? GO:0009055 ... P00131 1663945
    48265 2cym:A (2.0) BS03 HEM ? GO:0009055 ... P00131 1663945
    48266 2cym:A (2.0) BS04 HEM ? GO:0009055 ... P00131 1663945
    48267 2cyy:A (1.8) BS01 CA ? GO:0003677 ... O59188 N/A
    48268 2cyy:A (1.8) BS02 CA ? GO:0003677 ... O59188 N/A
    48269 2cyy:A (1.8) BS03 GLN ? GO:0003677 ... O59188 N/A
    48270 2cz2:A (1.4) BS01 GSH 2.5.1.18
    5.2.1.2
    GO:0003824 ... Q9WVL0 N/A
    48271 2czc:A (2.0) BS01 NAD 1.2.1.59 GO:0004365 ... O59494 N/A
    48272 2czc:B (2.0) BS01 NAD 1.2.1.59 GO:0004365 ... O59494 N/A
    48273 2czc:C (2.0) BS01 NAD 1.2.1.59 GO:0004365 ... O59494 N/A
    48274 2czc:D (2.0) BS01 NAD 1.2.1.59 GO:0004365 ... O59494 N/A
    48275 2cze:A (1.85) BS01 U5P 4.1.1.23 GO:0004590 ... O58462 N/A
    48276 2cze:A (1.85) BS02 U5P 4.1.1.23 GO:0004590 ... O58462 N/A
    48277 2cze:B (1.85) BS01 U5P 4.1.1.23 GO:0004590 ... O58462 N/A
    48278 2cze:B (1.85) BS02 U5P 4.1.1.23 GO:0004590 ... O58462 N/A
    48279 2czf:A (1.85) BS01 XMP 4.1.1.23 GO:0004590 ... O58462 N/A
    48280 2czf:B (1.85) BS01 XMP 4.1.1.23 GO:0004590 ... O58462 N/A
    48281 2czh:B (2.7) BS01 PO4 3.1.3.25 GO:0005515 ... O14732 17340635
    48282 2czi:A (3.0) BS01 CA 3.1.3.25 GO:0005515 ... O14732 17340635
    48283 2czi:A (3.0) BS02 CA 3.1.3.25 GO:0005515 ... O14732 17340635
    48284 2czi:A (3.0) BS03 PO4 3.1.3.25 GO:0005515 ... O14732 17340635
    48285 2d06:A (2.3) BS01 A3P 2.8.2.1 GO:0004062 ... P50225 16221673
    48286 2d06:A (2.3) BS02 EST 2.8.2.1 GO:0004062 ... P50225 16221673 MOAD: Ki=83.2uM
    PDBbind: -logKd/Ki=4.08, Ki=83.2uM
    BindingDB: Kd=1200nM
    48287 2d06:B (2.3) BS01 A3P 2.8.2.1 GO:0004062 ... P50225 16221673
    48288 2d06:B (2.3) BS02 EST 2.8.2.1 GO:0004062 ... P50225 16221673 MOAD: Ki=83.2uM
    BindingDB: Kd=1200nM
    48289 2d0b:A (2.1) BS01 MG 3.1.26.4 GO:0000287 ... Q6L6Q4 16343535
    48290 2d0c:A (2.6) BS01 MN 3.1.26.4 GO:0000287 ... Q6L6Q4 16343535
    48291 2d0f:A (2.08) BS01 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48292 2d0f:A (2.08) BS02 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48293 2d0f:A (2.08) BS03 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48294 2d0f:A (2.08) BS04 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48295 2d0f:A (2.08) BS05 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48296 2d0f:A (2.08) BS06 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48297 2d0f:A (2.08) BS07 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48298 2d0f:A (2.08) BS08 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48299 2d0f:A (2.08) BS09 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48300 2d0g:A (2.6) BS01 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48301 2d0g:A (2.6) BS02 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48302 2d0g:A (2.6) BS03 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48303 2d0g:A (2.6) BS04 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48304 2d0g:A (2.6) BS05 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48305 2d0g:A (2.6) BS06 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48306 2d0g:A (2.6) BS07 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48307 2d0g:A (2.6) BS08 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48308 2d0g:A (2.6) BS09 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48309 2d0g:A (2.6) BS10 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48310 2d0g:A (2.6) BS11 BGC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48311 2d0g:A (2.6) BS12 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48312 2d0g:A (2.6) BS13 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48313 2d0g:A (2.6) BS14 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48314 2d0h:A (2.1) BS01 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48315 2d0h:A (2.1) BS02 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48316 2d0h:A (2.1) BS03 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48317 2d0h:A (2.1) BS04 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48318 2d0h:A (2.1) BS05 GLC 3.2.1.135 GO:0004553 ... Q60053 16302977
    48319 2d0h:A (2.1) BS06 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48320 2d0h:A (2.1) BS07 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48321 2d0h:A (2.1) BS08 CA 3.2.1.135 GO:0004553 ... Q60053 16302977
    48322 2d0t:A (2.3) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 16477023
    48323 2d0t:A (2.3) BS02 PIM 1.13.11.52 GO:0002376 ... P14902 16477023 BindingDB: IC50=48000nM
    48324 2d0t:B (2.3) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 16477023
    48325 2d0t:B (2.3) BS02 PIM 1.13.11.52 GO:0002376 ... P14902 16477023 BindingDB: IC50=48000nM
    48326 2d0u:A (3.4) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 16477023
    48327 2d0u:B (3.4) BS01 HEM 1.13.11.52 GO:0002376 ... P14902 16477023
    48328 2d0v:A (2.49) BS01 CA 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48329 2d0v:A (2.49) BS02 PQQ 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48330 2d0v:D (2.49) BS01 CA 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48331 2d0v:D (2.49) BS02 PQQ 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48332 2d0v:I (2.49) BS01 CA 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48333 2d0v:I (2.49) BS02 PQQ 1.1.99.8 GO:0005509 ... Q4AE26 16533029
    48334 2d0w:A (1.98) BS01 ZN ? GO:0005506 ... Q4AE24 16533029
    48335 2d0w:A (1.98) BS02 ZN ? GO:0005506 ... Q4AE24 16533029
    48336 2d0w:A (1.98) BS03 ZN ? GO:0005506 ... Q4AE24 16533029
    48337 2d0w:A (1.98) BS04 HEM ? GO:0005506 ... Q4AE24 16533029
    48338 2d0w:B (1.98) BS01 ZN ? GO:0005506 ... Q4AE24 16533029
    48339 2d0w:B (1.98) BS02 ZN ? GO:0005506 ... Q4AE24 16533029
    48340 2d0w:B (1.98) BS03 ZN ? GO:0005506 ... Q4AE24 16533029
    48341 2d0w:B (1.98) BS04 HEM ? GO:0005506 ... Q4AE24 16533029
    48342 2d10:A (2.5) BS01 peptide ? GO:0003779 ... P26043 16615918
    48343 2d10:B (2.5) BS01 peptide ? GO:0003779 ... P26043 16615918
    48344 2d10:C (2.5) BS01 peptide ? GO:0003779 ... P26043 16615918
    48345 2d10:D (2.5) BS01 peptide ? GO:0003779 ... P26043 16615918
    48346 2d11:A (2.81) BS01 peptide ? GO:0003779 ... P26043 16615918
    48347 2d11:B (2.81) BS01 peptide ? GO:0003779 ... P26043 16615918
    48348 2d11:C (2.81) BS01 peptide ? GO:0003779 ... P26043 16615918
    48349 2d11:D (2.81) BS01 peptide ? GO:0003779 ... P26043 16615918
    48350 2d1f:A (2.5) BS01 PLP 4.2.3.1 GO:0004795 ... P9WG59 18621388
    48351 2d1f:B (2.5) BS01 PLP 4.2.3.1 GO:0004795 ... P9WG59 18621388
    48352 2d1k:A (2.5) BS01 peptide 3.6.4.- GO:0000287 ... P68135 17292833
    48353 2d1k:A (2.5) BS02 ATP 3.6.4.- GO:0000287 ... P68135 17292833
    48354 2d1k:B (2.5) BS01 peptide 3.1.21.1 GO:0002283 ... P00639 17292833
    48355 2d1k:B (2.5) BS02 CA 3.1.21.1 GO:0002283 ... P00639 17292833
    48356 2d1k:B (2.5) BS03 MG 3.1.21.1 GO:0002283 ... P00639 17292833
    48357 2d1n:A (2.37) BS01 ZN 3.4.24.- GO:0004222 ... P45452 16603129
    48358 2d1n:A (2.37) BS02 ZN 3.4.24.- GO:0004222 ... P45452 16603129
    48359 2d1n:A (2.37) BS03 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48360 2d1n:A (2.37) BS04 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48361 2d1n:A (2.37) BS05 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48362 2d1n:A (2.37) BS06 FA4 3.4.24.- GO:0004222 ... P45452 16603129 MOAD: Ki=0.007uM
    PDBbind: -logKd/Ki=8.15, Ki=7nM
    48363 2d1n:B (2.37) BS01 ZN 3.4.24.- GO:0004222 ... P45452 16603129
    48364 2d1n:B (2.37) BS02 ZN 3.4.24.- GO:0004222 ... P45452 16603129
    48365 2d1n:B (2.37) BS03 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48366 2d1n:B (2.37) BS04 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48367 2d1n:B (2.37) BS05 CA 3.4.24.- GO:0004222 ... P45452 16603129
    48368 2d1n:B (2.37) BS06 FA4 3.4.24.- GO:0004222 ... P45452 16603129 MOAD: Ki=0.007uM
    48369 2d1o:A (2.02) BS01 ZN 3.4.24.17 GO:0004222 ... P08254 16603129
    48370 2d1o:A (2.02) BS02 ZN 3.4.24.17 GO:0004222 ... P08254 16603129
    48371 2d1o:A (2.02) BS03 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48372 2d1o:A (2.02) BS04 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48373 2d1o:A (2.02) BS05 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48374 2d1o:A (2.02) BS06 FA4 3.4.24.17 GO:0004222 ... P08254 16603129 MOAD: Ki=0.02uM
    PDBbind: -logKd/Ki=7.70, Ki=0.02uM
    48375 2d1o:B (2.02) BS01 ZN 3.4.24.17 GO:0004222 ... P08254 16603129
    48376 2d1o:B (2.02) BS02 ZN 3.4.24.17 GO:0004222 ... P08254 16603129
    48377 2d1o:B (2.02) BS03 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48378 2d1o:B (2.02) BS04 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48379 2d1o:B (2.02) BS05 CA 3.4.24.17 GO:0004222 ... P08254 16603129
    48380 2d1o:B (2.02) BS06 FA4 3.4.24.17 GO:0004222 ... P08254 16603129 MOAD: Ki=0.02uM
    48381 2d1q:A (2.3) BS01 AMP 1.13.12.7 GO:0001676 ... P13129 16541080
    48382 2d1r:A (1.6) BS01 AMP 1.13.12.7 GO:0001676 ... P13129 16541080
    48383 2d1r:A (1.6) BS02 OLU 1.13.12.7 GO:0001676 ... P13129 16541080
    48384 2d1s:A (1.3) BS01 SLU 1.13.12.7 GO:0001676 ... P13129 16541080
    48385 2d1t:A (1.45) BS01 SLU 1.13.12.7 GO:0001676 ... P13129 16541080
    48386 2d2c:A (3.8) BS01 HEM ? GO:0009055 ... P83791 16371475
    48387 2d2c:A (3.8) BS02 HEM ? GO:0009055 ... P83791 16371475
    48388 2d2c:A (3.8) BS03 HEC ? GO:0009055 ... P83791 16371475
    48389 2d2c:B (3.8) BS01 peptide ? GO:0009055 ... P83792 16371475
    48390 2d2c:B (3.8) BS02 HEC ? GO:0009055 ... P83792 16371475
    48391 2d2c:B (3.8) BS03 BNT ? GO:0009055 ... P83792 16371475
    48392 2d2c:B (3.8) BS04 CLA ? GO:0009055 ... P83792 16371475
    48393 2d2c:C (3.8) BS01 peptide ? GO:0005506 ... P83793 16371475
    48394 2d2c:C (3.8) BS02 BNT ? GO:0005506 ... P83793 16371475
    48395 2d2c:C (3.8) BS03 HEM ? GO:0005506 ... P83793 16371475
    48396 2d2c:D (3.8) BS01 FES 7.1.1.6 GO:0005886 ... P83794 16371475
    48397 2d2c:F (3.8) BS01 peptide ? GO:0009055 ... P83796 16371475
    48398 2d2c:F (3.8) BS02 peptide ? GO:0009055 ... P83796 16371475
    48399 2d2c:N (3.8) BS01 HEM ? GO:0009055 ... P83791 16371475
    48400 2d2c:N (3.8) BS02 HEM ? GO:0009055 ... P83791 16371475

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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