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BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    2601 1bpw:C (2.8) BS01 NAD 1.2.1.3
    1.2.1.47
    GO:0004029 ... P56533 9792097
    2602 1bpw:D (2.8) BS01 NAD 1.2.1.3
    1.2.1.47
    GO:0004029 ... P56533 9792097
    2603 1bpx:A (2.4) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2604 1bpx:A (2.4) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2605 1bpx:A (2.4) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2606 1bpy:A (2.2) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2607 1bpy:A (2.2) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2608 1bpy:A (2.2) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2609 1bpy:A (2.2) BS04 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2610 1bpy:A (2.2) BS05 MG 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2611 1bpy:A (2.2) BS06 DCT 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2612 1bpz:A (2.6) BS01 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2613 1bpz:A (2.6) BS02 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2614 1bpz:A (2.6) BS03 dna 2.7.7.7
    4.2.99.-
    4.2.99.18
    GO:0001701 ... P06746 9287163
    2615 1bq1:A (2.5) BS01 UMP 2.1.1.45 GO:0000287 ... P0A884 9826509
    2616 1bq1:A (2.5) BS02 UMP 2.1.1.45 GO:0000287 ... P0A884 9826509
    2617 1bq1:B (2.5) BS01 UMP 2.1.1.45 GO:0000287 ... P0A884 9826509
    2618 1bq1:B (2.5) BS02 UMP 2.1.1.45 GO:0000287 ... P0A884 9826509
    2619 1bq3:A (2.7) BS01 IHP 5.4.2.11 GO:0003824 ... P00950 10369755
    2620 1bq3:D (2.7) BS01 IHP 5.4.2.11 GO:0003824 ... P00950 10369755 PDBbind: -logKd/Ki=5.40, Ki=4uM
    2621 1bq4:A (2.5) BS01 BHC 5.4.2.11 GO:0003824 ... P00950 10369755 MOAD: Ki=6uM
    PDBbind: -logKd/Ki=5.22, Ki=6uM
    2622 1bqk:A (1.35) BS01 CU ? GO:0005507 ... P19567 10364229
    2623 1bqo:A (2.3) BS01 ZN 3.4.24.17 GO:0004222 ... P08254 9733482
    2624 1bqo:A (2.3) BS02 ZN 3.4.24.17 GO:0004222 ... P08254 9733482
    2625 1bqo:A (2.3) BS03 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2626 1bqo:A (2.3) BS04 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2627 1bqo:A (2.3) BS05 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2628 1bqo:B (2.3) BS01 ZN 3.4.24.17 GO:0004222 ... P08254 9733482
    2629 1bqo:B (2.3) BS02 ZN 3.4.24.17 GO:0004222 ... P08254 9733482
    2630 1bqo:B (2.3) BS03 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2631 1bqo:B (2.3) BS04 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2632 1bqo:B (2.3) BS05 CA 3.4.24.17 GO:0004222 ... P08254 9733482
    2633 1bqo:B (2.3) BS06 N25 3.4.24.17 GO:0004222 ... P08254 9733482 MOAD: ic50=18.4nM
    PDBbind: -logKd/Ki=7.74, IC50=18.4nM
    BindingDB: IC50=18nM, Ki=18nM
    2634 1bqq:M (2.75) BS01 CA 3.4.24.80 GO:0004222 ... P50281 9724659
    2635 1bqq:M (2.75) BS02 ZN 3.4.24.80 GO:0004222 ... P50281 9724659
    2636 1bqq:M (2.75) BS03 ZN 3.4.24.80 GO:0004222 ... P50281 9724659
    2637 1bqq:M (2.75) BS04 CA 3.4.24.80 GO:0004222 ... P50281 9724659
    2638 1bqr:A (1.6) BS01 CU ? GO:0005507 ... P19567 10364229
    2639 1bqy:A (2.5) BS01 0GJ 3.4.21.- GO:0004252 ... Q91516 9753698
    2640 1bqy:B (2.5) BS01 0GJ 3.4.21.- GO:0004252 ... Q91516 9753698
    2641 1br1:A (3.5) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2642 1br1:A (3.5) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2643 1br1:A (3.5) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2644 1br1:C (3.5) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2645 1br1:C (3.5) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2646 1br1:C (3.5) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2647 1br1:E (3.5) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2648 1br1:E (3.5) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2649 1br1:E (3.5) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2650 1br1:G (3.5) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2651 1br1:G (3.5) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2652 1br1:G (3.5) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2653 1br2:A (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2654 1br2:A (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2655 1br2:A (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2656 1br2:B (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2657 1br2:B (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2658 1br2:B (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2659 1br2:C (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2660 1br2:C (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2661 1br2:C (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2662 1br2:D (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2663 1br2:D (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2664 1br2:D (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2665 1br2:E (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2666 1br2:E (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2667 1br2:E (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2668 1br2:F (2.9) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2669 1br2:F (2.9) BS02 ALF 3.6.1.32 GO:0003774 ... P10587 9741621
    2670 1br2:F (2.9) BS03 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2671 1br4:A (3.62) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2672 1br4:A (3.62) BS02 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2673 1br4:A (3.62) BS03 BEF 3.6.1.32 GO:0003774 ... P10587 9741621
    2674 1br4:C (3.62) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2675 1br4:C (3.62) BS02 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2676 1br4:C (3.62) BS03 BEF 3.6.1.32 GO:0003774 ... P10587 9741621
    2677 1br4:E (3.62) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2678 1br4:E (3.62) BS02 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2679 1br4:E (3.62) BS03 BEF 3.6.1.32 GO:0003774 ... P10587 9741621
    2680 1br4:G (3.62) BS01 MG 3.6.1.32 GO:0003774 ... P10587 9741621
    2681 1br4:G (3.62) BS02 ADP 3.6.1.32 GO:0003774 ... P10587 9741621
    2682 1br4:G (3.62) BS03 BEF 3.6.1.32 GO:0003774 ... P10587 9741621
    2683 1br8:I (2.9) BS01 peptide ? GO:0002020 ... P01008 9761669
    2684 1bra:A (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00763 8478942
    2685 1bra:A (2.2) BS02 BEN 3.4.21.4 GO:0004252 ... P00763 8478942 MOAD: Ki=15000uM
    PDBbind: -logKd/Ki=1.82, Ki=15000uM
    2686 1brd:A (3.5) BS01 RET ? GO:0005216 ... P02945 2359127
    2687 1brp:A (2.5) BS01 RTL ? GO:0001654 ... P02753 8464067
    2688 1brr:A (2.9) BS01 MAN ? GO:0005216 ... P02945 9751724
    2689 1brr:A (2.9) BS02 RET ? GO:0005216 ... P02945 9751724
    2690 1brr:A (2.9) BS03 ARC ? GO:0005216 ... P02945 9751724
    2691 1brr:A (2.9) BS04 ARC ? GO:0005216 ... P02945 9751724
    2692 1brr:A (2.9) BS05 ARC ? GO:0005216 ... P02945 9751724
    2693 1brr:A (2.9) BS06 ARC ? GO:0005216 ... P02945 9751724
    2694 1brr:A (2.9) BS07 ARC ? GO:0005216 ... P02945 9751724
    2695 1brr:B (2.9) BS01 GLC ? GO:0005216 ... P02945 9751724
    2696 1brr:B (2.9) BS02 RET ? GO:0005216 ... P02945 9751724
    2697 1brr:B (2.9) BS03 ARC ? GO:0005216 ... P02945 9751724
    2698 1brr:B (2.9) BS04 ARC ? GO:0005216 ... P02945 9751724
    2699 1brr:B (2.9) BS05 ARC ? GO:0005216 ... P02945 9751724
    2700 1brr:B (2.9) BS06 ARC ? GO:0005216 ... P02945 9751724
    2701 1brr:B (2.9) BS07 ARC ? GO:0005216 ... P02945 9751724
    2702 1brr:C (2.9) BS01 MAN ? GO:0005216 ... P02945 9751724
    2703 1brr:C (2.9) BS02 ARC ? GO:0005216 ... P02945 9751724
    2704 1brr:C (2.9) BS03 ARC ? GO:0005216 ... P02945 9751724
    2705 1brr:C (2.9) BS04 RET ? GO:0005216 ... P02945 9751724
    2706 1brr:C (2.9) BS05 ARC ? GO:0005216 ... P02945 9751724
    2707 1brr:C (2.9) BS06 ARC ? GO:0005216 ... P02945 9751724
    2708 1bru:P (2.3) BS01 1NB 3.4.21.71 GO:0004175 ... P08419 N/A
    2709 1brw:A (2.1) BS01 PO4 2.4.2.2 GO:0004645 ... P77836 9817849
    2710 1brw:A (2.1) BS02 CA 2.4.2.2 GO:0004645 ... P77836 9817849
    2711 1brw:B (2.1) BS01 PO4 2.4.2.2 GO:0004645 ... P77836 9817849
    2712 1brw:B (2.1) BS02 CA 2.4.2.2 GO:0004645 ... P77836 9817849
    2713 1brw:B (2.1) BS03 URA 2.4.2.2 GO:0004645 ... P77836 9817849
    2714 1brx:A (2.3) BS01 RET ? GO:0005216 ... P02945 9632391
    2715 1bs1:A (1.8) BS01 MG 6.3.3.3 GO:0000287 ... P13000 9865950
    2716 1bs1:A (1.8) BS02 ADP 6.3.3.3 GO:0000287 ... P13000 9865950
    2717 1bs1:A (1.8) BS03 DAA 6.3.3.3 GO:0000287 ... P13000 9865950
    2718 1bs2:A (2.75) BS01 ARG 6.1.1.19 GO:0000166 ... Q05506 9736621
    2719 1bs4:A (1.9) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2720 1bs4:B (1.9) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2721 1bs4:C (1.9) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2722 1bs5:A (2.5) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2723 1bs5:B (2.5) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2724 1bs5:C (2.5) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2725 1bs6:A (2.1) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2726 1bs6:B (2.1) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2727 1bs6:C (2.1) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2728 1bs8:A (2.2) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2729 1bs8:A (2.2) BS02 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2730 1bs8:B (2.2) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2731 1bs8:B (2.2) BS02 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2732 1bs8:C (2.2) BS01 peptide 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2733 1bs8:C (2.2) BS02 ZN 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2734 1bsi:A (2.0) BS01 CA 3.2.1.1 GO:0003824 ... P04746 10091666
    2735 1bsj:A (3.0) BS01 CO 3.5.1.88 GO:0005515 ... P0A6K3 10200158
    2736 1bsj:A (3.0) BS02 MLN 3.5.1.88 GO:0005515 ... P0A6K3 10200158
    2737 1bsk:A (3.0) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 10200158
    2738 1bsk:A (3.0) BS02 MLN 3.5.1.88 GO:0005515 ... P0A6K3 10200158 PDBbind: -logKd/Ki=4.12, Ki=76uM
    2739 1bso:A (2.23) BS01 BRC ? GO:0005515 ... P02754 9827560
    2740 1bsr:A (1.9) BS01 SO4 4.6.1.18 GO:0003676 ... P00669 15299514
    2741 1bsr:B (1.9) BS01 SO4 4.6.1.18 GO:0003676 ... P00669 15299514
    2742 1bsv:A (2.2) BS01 NDP 1.1.1.271 GO:0005737 ... P32055 9862812
    2743 1bsz:A (1.9) BS01 FE 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2744 1bsz:B (1.9) BS01 FE 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2745 1bsz:C (1.9) BS01 FE 3.5.1.88 GO:0005515 ... P0A6K3 9846875
    2746 1bt4:A (2.3) BS01 PLP 2.6.1.52 GO:0004648 ... Q59196 N/A
    2747 1bt6:A (2.4) BS01 peptide ? GO:0001765 ... P60903 9886297
    2748 1bt6:A (2.4) BS02 peptide ? GO:0001765 ... P60903 9886297
    2749 1bt6:B (2.4) BS01 peptide ? GO:0001765 ... P60903 9886297
    2750 1bt6:B (2.4) BS02 peptide ? GO:0001765 ... P60903 9886297
    2751 1btm:A (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 8580851
    2752 1btm:B (2.8) BS01 PGA 5.3.1.1 GO:0004807 ... P00943 8580851
    2753 1bto:A (2.0) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2754 1bto:A (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2755 1bto:A (2.0) BS03 NAD 1.1.1.1 GO:0004022 ... P00327 9003191
    2756 1bto:A (2.0) BS04 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2757 1bto:A (2.0) BS05 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2758 1bto:B (2.0) BS01 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2759 1bto:B (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2760 1bto:B (2.0) BS03 NAD 1.1.1.1 GO:0004022 ... P00327 9003191
    2761 1bto:B (2.0) BS04 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2762 1bto:B (2.0) BS05 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2763 1bto:C (2.0) BS01 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2764 1bto:C (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2765 1bto:C (2.0) BS03 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2766 1bto:C (2.0) BS04 NAD 1.1.1.1 GO:0004022 ... P00327 9003191
    2767 1bto:C (2.0) BS05 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2768 1bto:D (2.0) BS01 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2769 1bto:D (2.0) BS02 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2770 1bto:D (2.0) BS03 ZN 1.1.1.1 GO:0004022 ... P00327 9003191
    2771 1bto:D (2.0) BS04 NAD 1.1.1.1 GO:0004022 ... P00327 9003191
    2772 1bto:D (2.0) BS05 SSB 1.1.1.1 GO:0004022 ... P00327 9003191 MOAD: Ki=0.31uM
    2773 1btp:A (2.2) BS01 CA 3.4.21.4 GO:0004175 ... P00760 7548040
    2774 1btu:A (1.6) BS01 CA 3.4.21.36 GO:0004252 ... P00772 9860865
    2775 1btu:A (1.6) BS02 2BL 3.4.21.36 GO:0004252 ... P00772 9860865
    2776 1btw:A (1.7) BS01 0ZW 3.4.21.4 GO:0004175 ... P00760 7599119
    2777 1btw:A (1.7) BS02 CA 3.4.21.4 GO:0004175 ... P00760 7599119
    2778 1btx:A (1.7) BS01 0ZX 3.4.21.4 GO:0004175 ... P00760 7599119
    2779 1bty:A (1.5) BS01 CA 3.4.21.4 GO:0004175 ... P00760 7599119
    2780 1btz:A (2.0) BS01 0ZY 3.4.21.4 GO:0004175 ... P00760 7599119
    2781 1btz:A (2.0) BS02 CA 3.4.21.4 GO:0004175 ... P00760 7599119
    2782 1bu3:A (1.65) BS01 CA ? GO:0005509 ... P56503 10739249
    2783 1bu3:A (1.65) BS02 CA ? GO:0005509 ... P56503 10739249
    2784 1bu4:A (1.9) BS01 2GP 4.6.1.24 GO:0001411 ... P00651 10373011
    2785 1bu6:O (2.37) BS01 GOL 2.7.1.30 GO:0004370 ... P0A6F3 9817843
    2786 1bu6:X (2.37) BS01 GOL 2.7.1.30 GO:0004370 ... P0A6F3 9817843
    2787 1bu6:Y (2.37) BS01 GOL 2.7.1.30 GO:0004370 ... P0A6F3 9817843
    2788 1bu6:Z (2.37) BS01 GOL 2.7.1.30 GO:0004370 ... P0A6F3 9817843
    2789 1buv:M (2.75) BS01 CA 3.4.24.80 GO:0004222 ... P50281 9724659
    2790 1buv:M (2.75) BS02 ZN 3.4.24.80 GO:0004222 ... P50281 9724659
    2791 1buv:M (2.75) BS03 ZN 3.4.24.80 GO:0004222 ... P50281 9724659
    2792 1buv:M (2.75) BS04 CA 3.4.24.80 GO:0004222 ... P50281 9724659
    2793 1buw:A (1.9) BS01 HEM ? GO:0004601 ... P69905 9843411
    2794 1buw:A (1.9) BS02 NO ? GO:0004601 ... P69905 9843411
    2795 1buw:B (1.9) BS01 HEM ? GO:0004601 ... P68871 9843411
    2796 1buw:B (1.9) BS02 NO ? GO:0004601 ... P68871 9843411
    2797 1buw:C (1.9) BS01 HEM ? GO:0004601 ... P69905 9843411
    2798 1buw:C (1.9) BS02 NO ? GO:0004601 ... P69905 9843411
    2799 1buw:D (1.9) BS01 HEM ? GO:0004601 ... P68871 9843411
    2800 1buw:D (1.9) BS02 NO ? GO:0004601 ... P68871 9843411

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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