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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    10401 1evz:A (2.8) BS01 NAD 1.1.1.8 GO:0005829 ... P90551 10801498
    10402 1ew0:A (1.4) BS01 HEM 2.7.13.3 GO:0006355 ... P10955 10926518
    10403 1ew2:A (1.82) BS01 ZN 3.1.3.1 GO:0000287 ... P05187 11124260
    10404 1ew2:A (1.82) BS02 ZN 3.1.3.1 GO:0000287 ... P05187 11124260
    10405 1ew2:A (1.82) BS03 MG 3.1.3.1 GO:0000287 ... P05187 11124260
    10406 1ew2:A (1.82) BS04 MG 3.1.3.1 GO:0000287 ... P05187 11124260
    10407 1ew2:A (1.82) BS05 PO4 3.1.3.1 GO:0000287 ... P05187 11124260
    10408 1ew6:A (1.78) BS01 HEM ? GO:0004601 ... Q9NAV8 10751397
    10409 1ew6:B (1.78) BS01 HEM ? GO:0004601 ... Q9NAV8 10751397
    10410 1ew8:A (2.2) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10411 1ew8:A (2.2) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10412 1ew8:A (2.2) BS03 PO4 3.1.3.1 GO:0000287 ... P00634 10850800
    10413 1ew8:A (2.2) BS04 MG 3.1.3.1 GO:0000287 ... P00634 10850800
    10414 1ew8:A (2.2) BS05 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10415 1ew8:A (2.2) BS06 PAE 3.1.3.1 GO:0000287 ... P00634 10850800 MOAD: Ki=5.5mM
    PDBbind: -logKd/Ki=2.26, Ki=5.5mM
    10416 1ew8:B (2.2) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10417 1ew8:B (2.2) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10418 1ew8:B (2.2) BS03 PO4 3.1.3.1 GO:0000287 ... P00634 10850800
    10419 1ew8:B (2.2) BS04 MG 3.1.3.1 GO:0000287 ... P00634 10850800
    10420 1ew8:B (2.2) BS05 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10421 1ew8:B (2.2) BS06 PAE 3.1.3.1 GO:0000287 ... P00634 10850800 MOAD: Ki=5.5mM
    10422 1ew9:A (2.0) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10423 1ew9:A (2.0) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10424 1ew9:A (2.0) BS03 MG 3.1.3.1 GO:0000287 ... P00634 10850800
    10425 1ew9:A (2.0) BS04 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10426 1ew9:A (2.0) BS05 MMQ 3.1.3.1 GO:0000287 ... P00634 10850800 MOAD: Ki=0.6mM
    PDBbind: -logKd/Ki=3.22, Ki=0.6mM
    10427 1ew9:B (2.0) BS01 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10428 1ew9:B (2.0) BS02 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10429 1ew9:B (2.0) BS03 MG 3.1.3.1 GO:0000287 ... P00634 10850800
    10430 1ew9:B (2.0) BS04 ZN 3.1.3.1 GO:0000287 ... P00634 10850800
    10431 1ew9:B (2.0) BS05 MMQ 3.1.3.1 GO:0000287 ... P00634 10850800 MOAD: Ki=0.6mM
    PDBbind: -logKd/Ki=3.22, Ki=0.6mM
    10432 1ewa:A (2.5) BS01 HEM ? GO:0004601 ... Q9NAV8 10751397
    10433 1ewa:A (2.5) BS02 IOL ? GO:0004601 ... Q9NAV8 10751397
    10434 1ewa:B (2.5) BS01 HEM ? GO:0004601 ... Q9NAV8 10751397
    10435 1ewa:B (2.5) BS02 IOL ? GO:0004601 ... Q9NAV8 10751397
    10436 1ewc:A (1.95) BS01 ZN ? GO:0005576 ... P0A0M0 10986116
    10437 1ewh:A (2.35) BS01 HEC ? GO:0005506 ... P23577 10924110
    10438 1ewh:B (2.35) BS01 HEC ? GO:0005506 ... P23577 10924110
    10439 1ewh:C (2.35) BS01 HEC ? GO:0005506 ... P23577 10924110
    10440 1ewj:A (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052 PDBbind: -logKd/Ki=7.49, Kd=32nM
    10441 1ewj:A (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052 PDBbind: -logKd/Ki=7.49, Kd=32nM
    10442 1ewj:B (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052 PDBbind: -logKd/Ki=7.49, Kd=32nM
    10443 1ewj:B (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052 PDBbind: -logKd/Ki=7.49, Kd=32nM
    10444 1ewj:C (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10445 1ewj:C (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10446 1ewj:D (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10447 1ewj:D (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10448 1ewj:E (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10449 1ewj:E (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10450 1ewj:F (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10451 1ewj:F (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10452 1ewj:G (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10453 1ewj:G (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10454 1ewj:H (2.5) BS01 BLM ? GO:0046677 ... P13081 11134052
    10455 1ewj:H (2.5) BS02 BLM ? GO:0046677 ... P13081 11134052
    10456 1ewk:A (2.2) BS01 MG ? GO:0004930 ... P23385 11069170
    10457 1ewk:A (2.2) BS02 GLU ? GO:0004930 ... P23385 11069170
    10458 1ewk:B (2.2) BS01 MG ? GO:0004930 ... P23385 11069170
    10459 1ewk:B (2.2) BS02 GLU ? GO:0004930 ... P23385 11069170
    10460 1ewl:A (2.0) BS01 R99 3.4.22.51 GO:0006508 ... P25779 N/A
    10461 1ewm:A (2.0) BS01 RL2 3.4.22.51 GO:0006508 ... P25779 N/A
    10462 1ewn:A (2.1) BS01 dna 3.2.2.21 GO:0003677 ... P29372 11106395
    10463 1ewn:A (2.1) BS02 dna 3.2.2.21 GO:0003677 ... P29372 11106395
    10464 1ewo:A (2.1) BS01 VSC 3.4.22.51 GO:0006508 ... P25779 N/A
    10465 1ewp:A (1.75) BS01 0I5 3.4.22.51 GO:0006508 ... P25779 N/A
    10466 1ewq:A (2.2) BS01 dna ? GO:0003677 ... Q56215 11048710
    10467 1ewq:A (2.2) BS02 dna ? GO:0003677 ... Q56215 11048710
    10468 1ewq:B (2.2) BS01 dna ? GO:0003677 ... Q56215 11048710
    10469 1ewq:B (2.2) BS02 dna ? GO:0003677 ... Q56215 11048710
    10470 1ewy:A (2.38) BS01 FAD 1.18.1.2 GO:0016491 ... P21890 11053838
    10471 1ewy:B (2.38) BS01 FAD 1.18.1.2 GO:0016491 ... P21890 11053838
    10472 1ewy:C (2.38) BS01 FAD ? GO:0005515 ... P0A3C8 11053838
    10473 1ewy:C (2.38) BS02 FES ? GO:0005515 ... P0A3C8 11053838
    10474 1ex0:A (2.0) BS01 CA 2.3.2.13 GO:0003810 ... P00488 N/A
    10475 1ex0:B (2.0) BS01 CA 2.3.2.13 GO:0003810 ... P00488 N/A
    10476 1ex1:A (2.2) BS01 GLC 3.2.1.21 GO:0004553 ... Q9XEI3 10368285
    10477 1ex2:A (1.85) BS01 FRU 3.6.1.9 GO:0005737 ... Q02169 10841541
    10478 1ex2:A (1.85) BS02 PO4 3.6.1.9 GO:0005737 ... Q02169 10841541
    10479 1ex2:A (1.85) BS03 PO4 3.6.1.9 GO:0005737 ... Q02169 10841541
    10480 1ex2:B (1.85) BS01 PO4 3.6.1.9 GO:0005737 ... Q02169 10841541
    10481 1ex7:A (1.9) BS01 5GP 2.7.4.8 GO:0004385 ... P15454 11243817
    10482 1ex8:A (1.85) BS01 A4P 2.7.6.3 GO:0000287 ... P26281 11311059 MOAD: Kd=0.47uM
    PDBbind: -logKd/Ki=6.33, Kd=0.47uM
    10483 1ex9:A (2.54) BS01 CA 3.1.1.3 GO:0004806 ... P26876 10893416
    10484 1ex9:A (2.54) BS02 OCP 3.1.1.3 GO:0004806 ... P26876 10893416
    10485 1exa:A (1.59) BS01 394 ? GO:0003677 ... P13631 10841540
    10486 1exb:A (2.1) BS01 NDP 1.1.1.- GO:0002244 ... P62483 10884227
    10487 1exc:A (2.7) BS01 DUT 3.6.1.9 GO:0005737 ... Q02169 10841541
    10488 1exc:A (2.7) BS02 DUT 3.6.1.9 GO:0005737 ... Q02169 10841541
    10489 1exc:B (2.7) BS01 DUT 3.6.1.9 GO:0005737 ... Q02169 10841541
    10490 1exc:B (2.7) BS02 DUT 3.6.1.9 GO:0005737 ... Q02169 10841541
    10491 1exd:A (2.7) BS01 rna 6.1.1.18 GO:0000166 ... P00962 10881199 PDBbind: Kd=7.1nM
    10492 1exd:A (2.7) BS02 SO4 6.1.1.18 GO:0000166 ... P00962 10881199
    10493 1exd:A (2.7) BS03 A 6.1.1.18 GO:0000166 ... P00962 10881199
    10494 1exf:A (2.1) BS01 GLY 3.4.21.- GO:0004252 ... P09331 9048539
    10495 1exi:A (3.12) BS01 dna ? GO:0003677 ... P39075 11201751
    10496 1exi:A (3.12) BS02 118 ? GO:0003677 ... P39075 11201751
    10497 1exi:A (3.12) BS03 118 ? GO:0003677 ... P39075 11201751
    10498 1exj:A (3.0) BS01 dna ? GO:0003677 ... P39075 11201751
    10499 1exj:A (3.0) BS02 P4P ? GO:0003677 ... P39075 11201751
    10500 1exk:A (-1.00) BS01 ZN ? GO:0031072 ... P08622 10891270
    10501 1exk:A (-1.00) BS02 ZN ? GO:0031072 ... P08622 10891270
    10502 1exm:A (1.7) BS01 MG ? GO:0003746 ... P60338 N/A
    10503 1exm:A (1.7) BS02 GNP ? GO:0003746 ... P60338 N/A
    10504 1exp:A (1.8) BS01 G2F 3.2.1.8
    3.2.1.91
    GO:0004553 ... P07986 8564541
    10505 1exp:A (1.8) BS02 BGC 3.2.1.8
    3.2.1.91
    GO:0004553 ... P07986 8564541
    10506 1exr:A (1.0) BS01 CA ? GO:0005509 ... P07463 10966818
    10507 1exr:A (1.0) BS02 CA ? GO:0005509 ... P07463 10966818
    10508 1exr:A (1.0) BS03 CA ? GO:0005509 ... P07463 10966818
    10509 1exr:A (1.0) BS04 CA ? GO:0005509 ... P07463 10966818
    10510 1exv:A (2.4) BS01 NBG 2.4.1.1 GO:0000166 ... P06737 10980448
    10511 1exv:A (2.4) BS02 PLP 2.4.1.1 GO:0000166 ... P06737 10980448
    10512 1exv:A (2.4) BS03 700 2.4.1.1 GO:0000166 ... P06737 10980448 MOAD: ic50=45nM
    PDBbind: -logKd/Ki=7.35, IC50=45nM
    BindingDB: IC50=45nM
    10513 1exv:A (2.4) BS04 700 2.4.1.1 GO:0000166 ... P06737 10980448 MOAD: ic50=45nM
    PDBbind: -logKd/Ki=7.35, IC50=45nM
    BindingDB: IC50=45nM
    10514 1exv:B (2.4) BS01 700 2.4.1.1 GO:0000166 ... P06737 10980448 MOAD: ic50=45nM
    PDBbind: -logKd/Ki=7.35, IC50=45nM
    BindingDB: IC50=45nM
    10515 1exv:B (2.4) BS02 NBG 2.4.1.1 GO:0000166 ... P06737 10980448
    10516 1exv:B (2.4) BS03 PLP 2.4.1.1 GO:0000166 ... P06737 10980448
    10517 1exv:B (2.4) BS04 700 2.4.1.1 GO:0000166 ... P06737 10980448 MOAD: ic50=45nM
    PDBbind: -logKd/Ki=7.35, IC50=45nM
    BindingDB: IC50=45nM
    10518 1exw:A (2.4) BS01 HDS 3.1.2.22 GO:0002084 ... P45478 10801859 PDBbind: -logKd/Ki=3.90, Ki=125uM
    10519 1exx:A (1.67) BS01 961 ? GO:0003677 ... P13631 10841540
    10520 1exz:A (2.3) BS01 CA ? GO:0005173 ... P21583 10884405
    10521 1ey2:A (2.3) BS01 FE2 1.13.11.5 GO:0004411 ... Q93099 10876237
    10522 1ey3:A (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10523 1ey3:B (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10524 1ey3:B (2.3) BS02 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10525 1ey3:C (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10526 1ey3:C (2.3) BS02 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10527 1ey3:D (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10528 1ey3:E (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10529 1ey3:E (2.3) BS02 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10530 1ey3:F (2.3) BS01 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10531 1ey3:F (2.3) BS02 DAK 4.2.1.17
    5.3.3.8
    GO:0003824 ... P14604 11851409
    10532 1eye:A (1.7) BS01 MG 2.5.1.15 GO:0004156 ... P9WND1 11007651
    10533 1eye:A (1.7) BS02 PMM 2.5.1.15 GO:0004156 ... P9WND1 11007651
    10534 1eyf:A (-1.00) BS01 ZN 2.1.1.63
    2.1.1.n11
    GO:0003677 ... P06134 11284682
    10535 1eyg:A (2.8) BS01 dna ? GO:0003697 ... P0AGE0 10932248
    10536 1eyg:A (2.8) BS02 dna ? GO:0003697 ... P0AGE0 10932248
    10537 1eyg:B (2.8) BS01 dna ? GO:0003697 ... P0AGE0 10932248
    10538 1eyg:B (2.8) BS02 dna ? GO:0003697 ... P0AGE0 10932248
    10539 1eyg:C (2.8) BS01 dna ? GO:0003697 ... P0AGE0 10932248
    10540 1eyg:D (2.8) BS01 dna ? GO:0003697 ... P0AGE0 10932248
    10541 1eyg:D (2.8) BS02 dna ? GO:0003697 ... P0AGE0 10932248
    10542 1eyi:A (2.32) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 10913263
    10543 1eyi:A (2.32) BS02 MG 3.1.3.11 GO:0005737 ... P00636 10913263
    10544 1eyi:A (2.32) BS03 MG 3.1.3.11 GO:0005737 ... P00636 10913263
    10545 1eyi:A (2.32) BS04 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10546 1eyi:A (2.32) BS05 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10547 1eyj:A (2.28) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 10913263
    10548 1eyj:A (2.28) BS02 MG 3.1.3.11 GO:0005737 ... P00636 10913263
    10549 1eyj:A (2.28) BS03 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10550 1eyj:A (2.28) BS04 AMP 3.1.3.11 GO:0005737 ... P00636 10913263 BindingDB: IC50=1300nM
    10551 1eyj:B (2.28) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 10913263
    10552 1eyj:B (2.28) BS02 MG 3.1.3.11 GO:0005737 ... P00636 10913263
    10553 1eyj:B (2.28) BS03 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10554 1eyj:B (2.28) BS04 AMP 3.1.3.11 GO:0005737 ... P00636 10913263 BindingDB: IC50=1300nM
    10555 1eyk:A (2.23) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 10913263
    10556 1eyk:A (2.23) BS02 ZN 3.1.3.11 GO:0005737 ... P00636 10913263
    10557 1eyk:A (2.23) BS03 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10558 1eyk:A (2.23) BS04 AMP 3.1.3.11 GO:0005737 ... P00636 10913263 BindingDB: IC50=1300nM
    10559 1eyk:B (2.23) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 10913263
    10560 1eyk:B (2.23) BS02 ZN 3.1.3.11 GO:0005737 ... P00636 10913263
    10561 1eyk:B (2.23) BS03 PO4 3.1.3.11 GO:0005737 ... P00636 10913263
    10562 1eyk:B (2.23) BS04 AMP 3.1.3.11 GO:0005737 ... P00636 10913263 BindingDB: IC50=1300nM
    10563 1eyn:A (1.7) BS01 2AN 2.5.1.7 GO:0003824 ... P33038 10823915 MOAD: Kd=40.8uM
    10564 1eyq:A (1.85) BS01 NAR 5.5.1.6 GO:0009813 ... P28012 10966651
    10565 1eyq:B (1.85) BS01 NAR 5.5.1.6 GO:0009813 ... P28012 10966651
    10566 1eyr:A (2.2) BS01 CDP 2.7.7.43 GO:0005737 ... P0A0Z8 11113120
    10567 1eyr:B (2.2) BS01 CDP 2.7.7.43 GO:0005737 ... P0A0Z8 11113120
    10568 1eys:C (2.2) BS01 HEM N/A GO:0005506 ... N/A 11095707
    10569 1eys:C (2.2) BS02 HEM N/A GO:0005506 ... N/A 11095707
    10570 1eys:C (2.2) BS03 HEM N/A GO:0005506 ... N/A 11095707
    10571 1eys:C (2.2) BS04 HEM N/A GO:0005506 ... N/A 11095707
    10572 1eys:L (2.2) BS01 BCL N/A GO:0009772 ... N/A 11095707
    10573 1eys:L (2.2) BS02 BCL N/A GO:0009772 ... N/A 11095707
    10574 1eys:L (2.2) BS03 BPH N/A GO:0009772 ... N/A 11095707
    10575 1eys:L (2.2) BS04 FE N/A GO:0009772 ... N/A 11095707
    10576 1eys:L (2.2) BS05 BCL N/A GO:0009772 ... N/A 11095707
    10577 1eys:L (2.2) BS06 BPH N/A GO:0009772 ... N/A 11095707
    10578 1eys:L (2.2) BS07 MQ8 N/A GO:0009772 ... N/A 11095707
    10579 1eys:M (2.2) BS01 BCL N/A GO:0009772 ... N/A 11095707
    10580 1eys:M (2.2) BS02 BPH N/A GO:0009772 ... N/A 11095707
    10581 1eys:M (2.2) BS03 FE N/A GO:0009772 ... N/A 11095707
    10582 1eys:M (2.2) BS04 BCL N/A GO:0009772 ... N/A 11095707
    10583 1eys:M (2.2) BS05 BCL N/A GO:0009772 ... N/A 11095707
    10584 1eys:M (2.2) BS06 BPH N/A GO:0009772 ... N/A 11095707
    10585 1eys:M (2.2) BS07 MQ8 N/A GO:0009772 ... N/A 11095707
    10586 1eys:M (2.2) BS08 CRT N/A GO:0009772 ... N/A 11095707
    10587 1eyt:A (1.5) BS01 SF4 ? GO:0009055 ... P80176 11095707
    10588 1eyu:A (1.78) BS01 dna 3.1.21.4 GO:0003677 ... P23657 10903853
    10589 1eyu:A (1.78) BS02 dna 3.1.21.4 GO:0003677 ... P23657 10903853
    10590 1eyu:B (1.78) BS01 dna 3.1.21.4 GO:0003677 ... P23657 10903853
    10591 1eyu:B (1.78) BS02 dna 3.1.21.4 GO:0003677 ... P23657 10903853
    10592 1eyw:A (1.9) BS01 ZN 3.1.8.1 GO:0004063 ... P0A434 10871616
    10593 1eyw:A (1.9) BS02 ZN 3.1.8.1 GO:0004063 ... P0A434 10871616
    10594 1eyw:A (1.9) BS03 TEN 3.1.8.1 GO:0004063 ... P0A434 10871616
    10595 1eyw:A (1.9) BS04 PEL 3.1.8.1 GO:0004063 ... P0A434 10871616
    10596 1eyx:A (2.25) BS01 BLA ? GO:0009507 ... Q7SIG0 11134927
    10597 1eyx:B (2.25) BS01 peptide ? GO:0009507 ... Q7SIF9 11134927
    10598 1eyx:B (2.25) BS02 PUB ? GO:0009507 ... Q7SIF9 11134927
    10599 1eyx:L (2.25) BS01 peptide ? GO:0009507 ... Q7SIF9 11134927
    10600 1eyx:L (2.25) BS02 PUB ? GO:0009507 ... Q7SIF9 11134927

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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