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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    45801 1s77:D (2.69) BS05 POP 2.7.7.6 GO:0000428 ... P00573 15016374
    45802 1s7d:A (2.17) BS01 ZN ? GO:0008270 ... P76344 N/A
    45803 1s7d:A (2.17) BS02 ZN ? GO:0008270 ... P76344 N/A
    45804 1s7g:A (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45805 1s7g:A (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45806 1s7g:A (2.3) BS03 NAD 2.3.1.286 GO:0005737 ... O30124 15023335
    45807 1s7g:B (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45808 1s7g:B (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45809 1s7g:B (2.3) BS03 NAD 2.3.1.286 GO:0005737 ... O30124 15023335
    45810 1s7g:C (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45811 1s7g:C (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45812 1s7g:C (2.3) BS03 NAD 2.3.1.286 GO:0005737 ... O30124 15023335
    45813 1s7g:D (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45814 1s7g:D (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45815 1s7g:E (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    45816 1s7g:E (2.3) BS02 APR 2.3.1.286 GO:0005737 ... O30124 15023335
    45817 1s7l:A (2.3) BS01 COA 2.3.1.- GO:0005737 ... Q8ZPC0 15817456
    45818 1s7n:A (2.1) BS01 COA 2.3.1.- GO:0005737 ... Q8ZPC0 15817456
    45819 1s7n:B (2.1) BS01 COA 2.3.1.- GO:0005737 ... Q8ZPC0 15817456
    45820 1s7n:C (2.1) BS01 COA 2.3.1.- GO:0005737 ... Q8ZPC0 15817456
    45821 1s7n:D (2.1) BS01 COA 2.3.1.- GO:0005737 ... Q8ZPC0 15817456
    45822 1s7q:A (1.99) BS01 peptide ? GO:0001913 ... P01901 15100292
    45823 1s7r:A (2.95) BS01 peptide ? GO:0001913 ... P01901 15100292
    45824 1s7r:D (2.95) BS01 peptide ? GO:0001913 ... P01901 15100292
    45825 1s7s:A (1.99) BS01 peptide ? GO:0001913 ... P01901 15100292
    45826 1s7t:A (2.3) BS01 peptide ? GO:0001913 ... P01901 15100292
    45827 1s7t:D (2.3) BS01 peptide ? GO:0001913 ... P01901 15100292
    45828 1s7u:A (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45829 1s7u:D (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45830 1s7u:G (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45831 1s7u:J (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45832 1s7v:A (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45833 1s7v:D (2.2) BS01 peptide ? GO:0001913 ... P01899 15100292
    45834 1s7w:A (2.4) BS01 peptide ? GO:0001913 ... P01899 15100292
    45835 1s7w:D (2.4) BS01 peptide ? GO:0001913 ... P01899 15100292
    45836 1s7w:G (2.4) BS01 peptide ? GO:0001913 ... P01899 15100292
    45837 1s7w:J (2.4) BS01 peptide ? GO:0001913 ... P01899 15100292
    45838 1s7w:K (2.4) BS01 peptide ? GO:0001913 ... P01887 15100292
    45839 1s7x:A (2.41) BS01 peptide ? GO:0001913 ... P01899 15100292
    45840 1s7x:D (2.41) BS01 peptide ? GO:0001913 ... P01899 15100292
    45841 1s7x:G (2.41) BS01 peptide ? GO:0001913 ... P01899 15100292
    45842 1s7x:J (2.41) BS01 peptide ? GO:0001913 ... P01899 15100292
    45843 1s7x:K (2.41) BS01 peptide ? GO:0001913 ... P01887 15100292
    45844 1s7y:A (1.75) BS01 GLU ? GO:0015276 ... P42260 15721240 MOAD: Ki=1.4uM
    45845 1s7y:B (1.75) BS01 GLU ? GO:0015276 ... P42260 15721240
    45846 1s81:A (1.7) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    45847 1s81:A (1.7) BS02 EDO 3.4.21.4 GO:0004252 ... P00761 15005618
    45848 1s81:A (1.7) BS03 EDO 3.4.21.4 GO:0004252 ... P00761 15005618
    45849 1s81:A (1.7) BS04 EDO 3.4.21.4 GO:0004252 ... P00761 15005618
    45850 1s82:A (1.85) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    45851 1s82:A (1.85) BS02 EDO 3.4.21.4 GO:0004252 ... P00761 15005618
    45852 1s82:A (1.85) BS03 EDO 3.4.21.4 GO:0004252 ... P00761 15005618
    45853 1s82:A (1.85) BS04 SBE 3.4.21.4 GO:0004252 ... P00761 15005618
    45854 1s83:A (1.25) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    45855 1s83:A (1.25) BS02 MG 3.4.21.4 GO:0004252 ... P00761 15005618
    45856 1s83:A (1.25) BS03 4HA 3.4.21.4 GO:0004252 ... P00761 15005618
    45857 1s84:A (1.85) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    45858 1s84:A (1.85) BS02 DYB 3.4.21.4 GO:0004252 ... P00761 15005618
    45859 1s85:A (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    45860 1s85:A (2.2) BS02 SBZ 3.4.21.4 GO:0004252 ... P00761 15005618
    45861 1s89:A (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    PDBbind: -logKd/Ki=5.24, Ki=5.8uM
    45862 1s89:B (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    45863 1s89:C (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    45864 1s89:D (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    45865 1s89:E (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    45866 1s89:F (2.22) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki=5.8uM
    PDBbind: -logKd/Ki=5.24, Ki=5.8uM
    45867 1s8a:A (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45868 1s8a:B (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45869 1s8a:C (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45870 1s8a:D (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45871 1s8a:E (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45872 1s8a:F (2.2) BS01 PGA 4.2.3.3 GO:0005737 ... P0A731 15049687 MOAD: Ki~74uM
    45873 1s8c:A (2.19) BS01 BLA 1.14.14.18 GO:0004392 ... P09601 15049686
    45874 1s8e:A (2.3) BS01 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    45875 1s8e:A (2.3) BS02 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    45876 1s8e:B (2.3) BS01 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    45877 1s8e:B (2.3) BS02 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    45878 1s8f:A (1.77) BS01 GDP ? GO:0003924 ... P24408 15196914
    45879 1s8f:B (1.77) BS01 GDP ? GO:0003924 ... P24408 15196914
    45880 1s8j:A (2.3) BS01 NO3 ? GO:0005216 ... P02945 15109251
    45881 1s8j:A (2.3) BS02 RET ? GO:0005216 ... P02945 15109251
    45882 1s8l:A (2.3) BS01 RET ? GO:0005216 ... P02945 15109251
    45883 1s8n:A (1.482) BS01 AZI ? GO:0000160 ... P9WGM3 15341725
    45884 1s95:A (1.6) BS01 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    45885 1s95:A (1.6) BS02 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    45886 1s95:B (1.6) BS01 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    45887 1s95:B (1.6) BS02 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    45888 1s97:A (2.4) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45889 1s97:A (2.4) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45890 1s97:A (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45891 1s97:A (2.4) BS04 DCT 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45892 1s97:B (2.4) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45893 1s97:B (2.4) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45894 1s97:B (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45895 1s97:B (2.4) BS04 DCT 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45896 1s97:C (2.4) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45897 1s97:C (2.4) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45898 1s97:C (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45899 1s97:C (2.4) BS04 DCT 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45900 1s97:D (2.4) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45901 1s97:D (2.4) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45902 1s97:D (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45903 1s97:D (2.4) BS04 DCT 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45904 1s99:A (1.65) BS01 CA ? GO:0030975 ... O34911 15451668
    45905 1s9a:A (2.47) BS01 FE 1.13.11.- GO:0003824 ... O67987 15060064
    45906 1s9a:B (2.47) BS01 FE 1.13.11.- GO:0003824 ... O67987 15060064
    45907 1s9d:A (1.8) BS01 GDP 3.6.5.2 GO:0000139 ... P84080 14654833
    45908 1s9d:A (1.8) BS02 AFB 3.6.5.2 GO:0000139 ... P84080 14654833
    45909 1s9d:E (1.8) BS01 AFB ? GO:0005085 ... Q99418 14654833
    45910 1s9e:A (2.6) BS01 ADB 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 15115397
    45911 1s9f:A (2.0) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45912 1s9f:A (2.0) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45913 1s9f:A (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45914 1s9f:A (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45915 1s9f:A (2.0) BS05 DDY 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45916 1s9f:B (2.0) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45917 1s9f:B (2.0) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45918 1s9f:B (2.0) BS03 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45919 1s9f:B (2.0) BS04 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45920 1s9f:B (2.0) BS05 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45921 1s9f:B (2.0) BS06 DDY 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45922 1s9f:C (2.0) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45923 1s9f:C (2.0) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45924 1s9f:C (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45925 1s9f:C (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45926 1s9f:C (2.0) BS05 DDY 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45927 1s9f:D (2.0) BS01 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45928 1s9f:D (2.0) BS02 dna 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45929 1s9f:D (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45930 1s9f:D (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45931 1s9f:D (2.0) BS05 DDY 2.7.7.7 GO:0000287 ... Q97W02 15077104
    45932 1s9g:A (2.8) BS01 ABZ 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 15115397
    45933 1s9i:A (3.2) BS01 MG 2.7.12.2 GO:0004672 ... P36507 15543157
    45934 1s9i:A (3.2) BS02 ATP 2.7.12.2 GO:0004672 ... P36507 15543157
    45935 1s9i:A (3.2) BS03 5EA 2.7.12.2 GO:0004672 ... P36507 15543157
    45936 1s9i:B (3.2) BS01 MG 2.7.12.2 GO:0004672 ... P36507 15543157
    45937 1s9i:B (3.2) BS02 ATP 2.7.12.2 GO:0004672 ... P36507 15543157
    45938 1s9i:B (3.2) BS03 5EA 2.7.12.2 GO:0004672 ... P36507 15543157
    45939 1s9j:A (2.4) BS01 MG 2.7.12.2 GO:0004672 ... Q02750 15543157
    45940 1s9j:A (2.4) BS02 ATP 2.7.12.2 GO:0004672 ... Q02750 15543157
    45941 1s9j:A (2.4) BS03 BBM 2.7.12.2 GO:0004672 ... Q02750 15543157
    45942 1s9k:C (3.1) BS01 dna ? GO:0003677 ... Q13469 N/A
    45943 1s9k:C (3.1) BS02 dna ? GO:0003677 ... Q13469 N/A
    45944 1s9k:D (3.1) BS01 dna ? GO:0003677 ... P01100 N/A
    45945 1s9k:D (3.1) BS02 dna ? GO:0003677 ... P01100 N/A
    45946 1s9k:E (3.1) BS01 dna ? GO:0003677 ... P05412 N/A
    45947 1s9k:E (3.1) BS02 dna ? GO:0003677 ... P05412 N/A
    45948 1s9r:A (1.6) BS01 ARG 3.5.3.6 GO:0005737 ... P23793 15062088
    45949 1s9r:B (1.6) BS01 ARG 3.5.3.6 GO:0005737 ... P23793 15062088
    45950 1s9t:A (1.8) BS01 QUS ? GO:0015276 ... P42260 15721240 MOAD: Ki=253nM
    PDBbind: -logKd/Ki=6.82, IC50=0.15uM
    BindingDB: Ki=134nM
    45951 1s9t:B (1.8) BS01 QUS ? GO:0015276 ... P42260 15721240 MOAD: Ki=253nM
    BindingDB: Ki=134nM
    45952 1s9v:A (2.22) BS01 peptide ? GO:0006955 ... P01909 15020763
    45953 1s9v:B (2.22) BS01 peptide ? GO:0006955 ... P01920 15020763
    45954 1s9v:D (2.22) BS01 peptide ? GO:0006955 ... P01909 15020763
    45955 1s9v:E (2.22) BS01 peptide ? GO:0006955 ... P01920 15020763
    45956 1sa0:A (3.58) BS01 GTP 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45957 1sa0:A (3.58) BS02 CN2 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45958 1sa0:B (3.58) BS01 GDP ? GO:0000226 ... Q6B856 15014504
    45959 1sa0:B (3.58) BS02 CN2 ? GO:0000226 ... Q6B856 15014504
    45960 1sa0:C (3.58) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45961 1sa0:C (3.58) BS02 GTP 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45962 1sa0:C (3.58) BS03 CN2 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45963 1sa0:D (3.58) BS01 GDP ? GO:0000226 ... Q6B856 15014504
    45964 1sa0:D (3.58) BS02 CN2 ? GO:0000226 ... Q6B856 15014504
    45965 1sa1:A (4.2) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45966 1sa1:A (4.2) BS02 GTP 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45967 1sa1:B (4.2) BS01 GDP ? GO:0000226 ... Q6B856 15014504
    45968 1sa1:B (4.2) BS02 POD ? GO:0000226 ... Q6B856 15014504 BindingDB: IC50=460nM
    45969 1sa1:C (4.2) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45970 1sa1:C (4.2) BS02 GTP 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    45971 1sa1:D (4.2) BS01 GDP ? GO:0000226 ... Q6B856 15014504
    45972 1sa1:D (4.2) BS02 POD ? GO:0000226 ... Q6B856 15014504 BindingDB: IC50=460nM
    45973 1sa3:A (1.95) BS01 dna 3.1.21.4 GO:0003677 ... P11405 15341737
    45974 1sa3:A (1.95) BS02 dna 3.1.21.4 GO:0003677 ... P11405 15341737
    45975 1sa3:B (1.95) BS01 dna 3.1.21.4 GO:0003677 ... P11405 15341737
    45976 1sa3:B (1.95) BS02 dna 3.1.21.4 GO:0003677 ... P11405 15341737
    45977 1sa4:A (2.1) BS01 GLC 2.5.1.58
    2.5.1.59
    GO:0004659 ... P49354 15170324
    45978 1sa4:A (2.1) BS02 FPP 2.5.1.58
    2.5.1.59
    GO:0004659 ... P49354 15170324 BindingDB: Kd=2.0nM
    45979 1sa4:B (2.1) BS01 GLC 2.5.1.58 GO:0003824 ... P49356 15170324
    45980 1sa4:B (2.1) BS02 FRU 2.5.1.58 GO:0003824 ... P49356 15170324
    45981 1sa4:B (2.1) BS03 ZN 2.5.1.58 GO:0003824 ... P49356 15170324
    45982 1sa4:B (2.1) BS04 FPP 2.5.1.58 GO:0003824 ... P49356 15170324
    45983 1sa4:B (2.1) BS05 JAN 2.5.1.58 GO:0003824 ... P49356 15170324 BindingDB: IC50=0.860nM
    45984 1sa5:A (2.6) BS01 FPP 2.5.1.58
    2.5.1.59
    GO:0004659 ... Q04631 15170324
    45985 1sa5:B (2.6) BS01 ZN 2.5.1.58 GO:0003824 ... Q02293 15170324
    45986 1sa5:B (2.6) BS02 FPP 2.5.1.58 GO:0003824 ... Q02293 15170324
    45987 1sa5:B (2.6) BS03 BMV 2.5.1.58 GO:0003824 ... Q02293 15170324
    45988 1sac:A (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    45989 1sac:A (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    45990 1sac:B (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    45991 1sac:B (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    45992 1sac:C (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    45993 1sac:C (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    45994 1sac:D (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    45995 1sac:D (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    45996 1sac:E (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    45997 1sac:E (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    45998 1sat:A (1.75) BS01 ZN 3.4.24.40 GO:0001907 ... P23694 8089845
    45999 1sat:A (1.75) BS02 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    46000 1sat:A (1.75) BS03 CA 3.4.24.40 GO:0001907 ... P23694 8089845

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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