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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    38801 1po2:1 (2.9) BS01 J77 2.7.7.48
    3.4.22.28
    3.4.22.29
    3.6.1.15
    GO:0005198 ... P03300 15299887
    38802 1po2:4 (2.9) BS01 peptide 2.7.7.48
    3.4.22.28
    3.4.22.29
    3.6.1.15
    GO:0005198 ... P03300 15299887
    38803 1po3:A (3.4) BS01 FLC ? GO:0005515 ... P13036 12948487
    38804 1po3:A (3.4) BS02 FLC ? GO:0005515 ... P13036 12948487
    38805 1po3:B (3.4) BS01 FLC ? GO:0005515 ... P13036 12948487
    38806 1po3:B (3.4) BS02 FLC ? GO:0005515 ... P13036 12948487
    38807 1po5:A (1.6) BS01 HEM 1.14.14.1 GO:0004497 ... P00178 14563924
    38808 1po6:A (2.1) BS01 dna ? GO:0003676 ... P09651 12904298 PDBbind: Kd=157nM
    38809 1po7:A (1.2) BS01 MG 4.1.1.7 GO:0000287 ... P20906 N/A
    38810 1po7:A (1.2) BS02 CA 4.1.1.7 GO:0000287 ... P20906 N/A
    38811 1po7:A (1.2) BS03 TZD 4.1.1.7 GO:0000287 ... P20906 N/A
    38812 1po8:A (2.71) BS01 SHV 3.1.1.4 GO:0004623 ... Q9DF52 N/A
    38813 1po9:A (2.0) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38814 1po9:A (2.0) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38815 1po9:B (2.0) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38816 1po9:B (2.0) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38817 1poa:A (1.5) BS01 CA 3.1.1.4 GO:0004623 ... P00598 2274785
    38818 1poa:A (1.5) BS02 CA 3.1.1.4 GO:0004623 ... P00598 2274785
    38819 1pob:A (2.0) BS01 CA 3.1.1.4 GO:0004623 ... P00598 2274787
    38820 1pob:A (2.0) BS02 CA 3.1.1.4 GO:0004623 ... P00598 2274787
    38821 1pob:A (2.0) BS03 GEL 3.1.1.4 GO:0004623 ... P00598 2274787
    38822 1pob:B (2.0) BS01 CA 3.1.1.4 GO:0004623 ... P00598 2274787
    38823 1pob:B (2.0) BS02 CA 3.1.1.4 GO:0004623 ... P00598 2274787
    38824 1pob:B (2.0) BS03 GEL 3.1.1.4 GO:0004623 ... P00598 2274787
    38825 1poc:A (2.0) BS01 CA 3.1.1.4 GO:0004623 ... P00630 2274788
    38826 1poc:A (2.0) BS02 GEL 3.1.1.4 GO:0004623 ... P00630 2274788
    38827 1pod:A (2.1) BS01 CA 3.1.1.4 GO:0004623 ... P14555 1948070
    38828 1poe:A (2.1) BS01 CA 3.1.1.4 GO:0004623 ... P14555 1948070
    38829 1poe:A (2.1) BS02 CA 3.1.1.4 GO:0004623 ... P14555 1948070
    38830 1poe:A (2.1) BS03 GEL 3.1.1.4 GO:0004623 ... P14555 1948070
    38831 1poe:B (2.1) BS01 CA 3.1.1.4 GO:0004623 ... P14555 1948070
    38832 1poe:B (2.1) BS02 CA 3.1.1.4 GO:0004623 ... P14555 1948070
    38833 1poe:B (2.1) BS03 GEL 3.1.1.4 GO:0004623 ... P14555 1948070
    38834 1poh:A (2.0) BS01 SO4 ? GO:0004857 ... P0AA04 8226757
    38835 1poj:A (3.3) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38836 1poj:A (3.3) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38837 1poj:A (3.3) BS03 AE1 3.4.19.- GO:0005737 ... P39377 12946361
    38838 1poj:B (3.3) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38839 1poj:B (3.3) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38840 1poj:B (3.3) BS03 AE1 3.4.19.- GO:0005737 ... P39377 12946361
    38841 1pok:A (2.7) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38842 1pok:A (2.7) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38843 1pok:A (2.7) BS03 ASN 3.4.19.- GO:0005737 ... P39377 12946361
    38844 1pok:B (2.7) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38845 1pok:B (2.7) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12946361
    38846 1pok:B (2.7) BS03 ASN 3.4.19.- GO:0005737 ... P39377 12946361
    38847 1poo:A (2.1) BS01 CA 3.1.3.8 GO:0005576 ... O66037 10655618
    38848 1poo:A (2.1) BS02 CA 3.1.3.8 GO:0005576 ... O66037 10655618
    38849 1pop:A (2.1) BS01 peptide 3.4.22.2 GO:0006508 ... P00784 8416808
    38850 1pot:A (1.8) BS01 SPD ? GO:0015846 ... P0AFK9 8897598 MOAD: Kd=3.2uM
    PDBbind: -logKd/Ki=5.49, Kd=3.2uM
    38851 1pow:A (2.5) BS01 MG 1.2.3.3 GO:0000287 ... P37063 8145244
    38852 1pow:A (2.5) BS02 TPP 1.2.3.3 GO:0000287 ... P37063 8145244
    38853 1pow:A (2.5) BS03 FAD 1.2.3.3 GO:0000287 ... P37063 8145244
    38854 1pow:B (2.5) BS01 MG 1.2.3.3 GO:0000287 ... P37063 8145244
    38855 1pow:B (2.5) BS02 TPP 1.2.3.3 GO:0000287 ... P37063 8145244
    38856 1pow:B (2.5) BS03 FAD 1.2.3.3 GO:0000287 ... P37063 8145244
    38857 1pox:A (2.1) BS01 MG 1.2.3.3 GO:0000287 ... P37063 8145244
    38858 1pox:A (2.1) BS02 TPP 1.2.3.3 GO:0000287 ... P37063 8145244
    38859 1pox:A (2.1) BS03 FAD 1.2.3.3 GO:0000287 ... P37063 8145244
    38860 1pox:B (2.1) BS01 MG 1.2.3.3 GO:0000287 ... P37063 8145244
    38861 1pox:B (2.1) BS02 TPP 1.2.3.3 GO:0000287 ... P37063 8145244
    38862 1pox:B (2.1) BS03 FAD 1.2.3.3 GO:0000287 ... P37063 8145244
    38863 1poy:1 (2.5) BS01 SPD ? GO:0015846 ... P0AFK9 8621624 MOAD: Kd=3.2uM
    38864 1poy:2 (2.5) BS01 SPD ? GO:0015846 ... P0AFK9 8621624 MOAD: Kd=3.2uM
    38865 1poy:3 (2.5) BS01 SPD ? GO:0015846 ... P0AFK9 8621624 MOAD: Kd=3.2uM
    38866 1poy:4 (2.5) BS01 SPD ? GO:0015846 ... P0AFK9 8621624 MOAD: Kd=3.2uM
    38867 1pp9:A (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P31800 16024040
    38868 1pp9:A (2.1) BS02 AZI 1.10.2.2 GO:0005739 ... P31800 16024040
    38869 1pp9:B (2.1) BS01 JZR 1.10.2.2 GO:0004222 ... P23004 16024040
    38870 1pp9:C (2.1) BS01 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38871 1pp9:C (2.1) BS02 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38872 1pp9:C (2.1) BS03 SMA 1.10.2.2 GO:0005739 ... P00157 16024040
    38873 1pp9:C (2.1) BS04 UQ 1.10.2.2 GO:0005739 ... P00157 16024040
    38874 1pp9:D (2.1) BS01 HEC 7.1.1.8 GO:0009055 ... P00125 16024040
    38875 1pp9:E (2.1) BS01 FES 7.1.1.8 GO:0008121 ... P13272 16024040
    38876 1pp9:E (2.1) BS02 SMA 7.1.1.8 GO:0008121 ... P13272 16024040
    38877 1pp9:F (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00129 16024040
    38878 1pp9:G (2.1) BS01 AZI 1.10.2.2 GO:0005739 ... P13271 16024040
    38879 1pp9:O (2.1) BS01 JZR 1.10.2.2 GO:0004222 ... P23004 16024040
    38880 1pp9:P (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00157 16024040
    38881 1pp9:P (2.1) BS02 AZI 1.10.2.2 GO:0005739 ... P00157 16024040
    38882 1pp9:P (2.1) BS03 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38883 1pp9:P (2.1) BS04 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38884 1pp9:P (2.1) BS05 SMA 1.10.2.2 GO:0005739 ... P00157 16024040
    38885 1pp9:P (2.1) BS06 UQ 1.10.2.2 GO:0005739 ... P00157 16024040
    38886 1pp9:Q (2.1) BS01 HEC 7.1.1.8 GO:0009055 ... P00125 16024040
    38887 1pp9:R (2.1) BS01 SMA 7.1.1.8 GO:0008121 ... P13272 16024040
    38888 1pp9:R (2.1) BS02 FES 7.1.1.8 GO:0008121 ... P13272 16024040
    38889 1pp9:S (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00129 16024040
    38890 1ppa:A (2.0) BS01 ANL 3.1.1.4 GO:0004623 ... P04361 2120215
    38891 1ppb:H (1.92) BS01 0G6 3.4.21.5 GO:0004252 ... P00734 2583108
    38892 1ppc:E (1.8) BS01 MID 3.4.21.4 GO:0004175 ... P00760 2226434 MOAD: Ki=0.69uM
    PDBbind: -logKd/Ki=6.16, Ki=0.69uM
    BindingDB: Ki=325nM
    38893 1ppc:E (1.8) BS02 CA 3.4.21.4 GO:0004175 ... P00760 2226434
    38894 1ppe:E (2.0) BS01 peptide 3.4.21.4 GO:0004175 ... P00760 2914611
    38895 1ppf:E (1.8) BS01 FUC 3.4.21.37 GO:0000122 ... P08246 3640709
    38896 1ppg:E (2.3) BS01 peptide 3.4.21.37 GO:0000122 ... P08246 3391280
    38897 1ppg:E (2.3) BS02 FUC 3.4.21.37 GO:0000122 ... P08246 3391280
    38898 1ppg:E (2.3) BS03 FUC 3.4.21.37 GO:0000122 ... P08246 3391280
    38899 1pph:E (1.9) BS01 CA 3.4.21.4 GO:0004175 ... P00760 1879520
    38900 1pph:E (1.9) BS02 0ZG 3.4.21.4 GO:0004175 ... P00760 1879520 MOAD: Ki=1.2uM
    PDBbind: -logKd/Ki=5.92, Ki=1.2uM
    BindingDB: Ki=99999999999999nM
    38901 1ppi:A (2.2) BS01 GLC 3.2.1.1 GO:0003824 ... P00690 8193143 PDBbind: -logKd/Ki=5.01, Ki=9.7uM
    38902 1ppi:A (2.2) BS02 GLC 3.2.1.1 GO:0003824 ... P00690 8193143 PDBbind: -logKd/Ki=5.01, Ki=9.7uM
    38903 1ppi:A (2.2) BS03 BGC 3.2.1.1 GO:0003824 ... P00690 8193143 PDBbind: -logKd/Ki=5.01, Ki=9.7uM
    38904 1ppi:A (2.2) BS04 DAF 3.2.1.1 GO:0003824 ... P00690 8193143 PDBbind: -logKd/Ki=5.01, Ki=9.7uM
    38905 1ppi:A (2.2) BS05 CL 3.2.1.1 GO:0003824 ... P00690 8193143
    38906 1ppi:A (2.2) BS06 CA 3.2.1.1 GO:0003824 ... P00690 8193143
    38907 1ppj:A (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P31800 16024040
    38908 1ppj:A (2.1) BS02 AZI 1.10.2.2 GO:0005739 ... P31800 16024040
    38909 1ppj:B (2.1) BS01 JZR 1.10.2.2 GO:0004222 ... P23004 16024040
    38910 1ppj:C (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00157 16024040
    38911 1ppj:C (2.1) BS02 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38912 1ppj:C (2.1) BS03 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38913 1ppj:C (2.1) BS04 SMA 1.10.2.2 GO:0005739 ... P00157 16024040
    38914 1ppj:C (2.1) BS05 ANY 1.10.2.2 GO:0005739 ... P00157 16024040
    38915 1ppj:D (2.1) BS01 JZR 7.1.1.8 GO:0009055 ... P00125 16024040
    38916 1ppj:D (2.1) BS02 HEC 7.1.1.8 GO:0009055 ... P00125 16024040
    38917 1ppj:E (2.1) BS01 FES 7.1.1.8 GO:0008121 ... P13272 16024040
    38918 1ppj:E (2.1) BS02 SMA 7.1.1.8 GO:0008121 ... P13272 16024040
    38919 1ppj:F (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00129 16024040
    38920 1ppj:G (2.1) BS01 AZI 1.10.2.2 GO:0005739 ... P13271 16024040
    38921 1ppj:O (2.1) BS01 JZR 1.10.2.2 GO:0004222 ... P23004 16024040
    38922 1ppj:P (2.1) BS01 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38923 1ppj:P (2.1) BS02 HEM 1.10.2.2 GO:0005739 ... P00157 16024040
    38924 1ppj:P (2.1) BS03 SMA 1.10.2.2 GO:0005739 ... P00157 16024040
    38925 1ppj:P (2.1) BS04 ANY 1.10.2.2 GO:0005739 ... P00157 16024040
    38926 1ppj:Q (2.1) BS01 HEC 7.1.1.8 GO:0009055 ... P00125 16024040
    38927 1ppj:R (2.1) BS01 SMA 7.1.1.8 GO:0008121 ... P13272 16024040
    38928 1ppj:R (2.1) BS02 FES 7.1.1.8 GO:0008121 ... P13272 16024040
    38929 1ppj:S (2.1) BS01 JZR 1.10.2.2 GO:0005739 ... P00129 16024040
    38930 1ppk:E (1.8) BS01 IVV 3.4.23.20 GO:0004190 ... P00798 1606144 MOAD: Ki=22nM
    PDBbind: -logKd/Ki=7.66, Ki=22nM
    38931 1ppl:E (1.7) BS01 1Z7 3.4.23.20 GO:0004190 ... P00798 1606144 MOAD: Ki=2.8nM
    PDBbind: -logKd/Ki=8.55, Ki=2.8nM
    38932 1ppm:E (1.7) BS01 0P1 3.4.23.20 GO:0004190 ... P00798 1606144 MOAD: Ki=1600nM
    PDBbind: -logKd/Ki=5.80, Ki=1600nM
    38933 1ppp:A (1.9) BS01 E6C 3.4.22.2 GO:0006508 ... P00784 1445241
    38934 1ppr:M (2.0) BS01 CLA ? GO:0016168 ... P80484 8650577
    38935 1ppr:M (2.0) BS02 CLA ? GO:0016168 ... P80484 8650577
    38936 1ppr:M (2.0) BS03 PID ? GO:0016168 ... P80484 8650577
    38937 1ppr:M (2.0) BS04 PID ? GO:0016168 ... P80484 8650577
    38938 1ppr:M (2.0) BS05 PID ? GO:0016168 ... P80484 8650577
    38939 1ppr:M (2.0) BS06 PID ? GO:0016168 ... P80484 8650577
    38940 1ppr:M (2.0) BS07 PID ? GO:0016168 ... P80484 8650577
    38941 1ppr:M (2.0) BS08 PID ? GO:0016168 ... P80484 8650577
    38942 1ppr:M (2.0) BS09 PID ? GO:0016168 ... P80484 8650577
    38943 1ppr:M (2.0) BS10 PID ? GO:0016168 ... P80484 8650577
    38944 1ppr:N (2.0) BS01 CLA ? GO:0016168 ... P80484 8650577
    38945 1ppr:N (2.0) BS02 CLA ? GO:0016168 ... P80484 8650577
    38946 1ppr:N (2.0) BS03 PID ? GO:0016168 ... P80484 8650577
    38947 1ppr:N (2.0) BS04 PID ? GO:0016168 ... P80484 8650577
    38948 1ppr:N (2.0) BS05 PID ? GO:0016168 ... P80484 8650577
    38949 1ppr:N (2.0) BS06 PID ? GO:0016168 ... P80484 8650577
    38950 1ppr:N (2.0) BS07 PID ? GO:0016168 ... P80484 8650577
    38951 1ppr:N (2.0) BS08 PID ? GO:0016168 ... P80484 8650577
    38952 1ppr:N (2.0) BS09 PID ? GO:0016168 ... P80484 8650577
    38953 1ppr:N (2.0) BS10 PID ? GO:0016168 ... P80484 8650577
    38954 1ppr:O (2.0) BS01 CLA ? GO:0016168 ... P80484 8650577
    38955 1ppr:O (2.0) BS02 CLA ? GO:0016168 ... P80484 8650577
    38956 1ppr:O (2.0) BS03 PID ? GO:0016168 ... P80484 8650577
    38957 1ppr:O (2.0) BS04 PID ? GO:0016168 ... P80484 8650577
    38958 1ppr:O (2.0) BS05 PID ? GO:0016168 ... P80484 8650577
    38959 1ppr:O (2.0) BS06 PID ? GO:0016168 ... P80484 8650577
    38960 1ppr:O (2.0) BS07 PID ? GO:0016168 ... P80484 8650577
    38961 1ppr:O (2.0) BS08 PID ? GO:0016168 ... P80484 8650577
    38962 1ppr:O (2.0) BS09 PID ? GO:0016168 ... P80484 8650577
    38963 1ppr:O (2.0) BS10 PID ? GO:0016168 ... P80484 8650577
    38964 1ppv:A (1.7) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    38965 1ppv:A (1.7) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    38966 1ppv:A (1.7) BS03 BHI 5.3.3.2 GO:0000287 ... Q46822 15643873
    38967 1ppv:B (1.7) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    38968 1ppv:B (1.7) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    38969 1ppv:B (1.7) BS03 BHI 5.3.3.2 GO:0000287 ... Q46822 15643873
    38970 1ppw:A (2.21) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    38971 1ppw:A (2.21) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    38972 1ppw:A (2.21) BS03 EIP 5.3.3.2 GO:0000287 ... Q46822 15643873 MOAD: ic50~50uM
    PDBbind: -logKd/Ki=4.30, IC50=50uM
    38973 1ppw:B (2.21) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    38974 1ppw:B (2.21) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    38975 1ppw:B (2.21) BS03 EIP 5.3.3.2 GO:0000287 ... Q46822 15643873 MOAD: ic50~50uM
    38976 1ppx:A (-1.00) BS01 MG 3.6.1.55 GO:0000287 ... P08337 12939141
    38977 1pq2:A (2.7) BS01 HEM 1.14.14.1 GO:0002933 ... P10632 14676196
    38978 1pq2:A (2.7) BS02 PLM 1.14.14.1 GO:0002933 ... P10632 14676196
    38979 1pq2:B (2.7) BS01 PLM 1.14.14.1 GO:0002933 ... P10632 14676196
    38980 1pq2:B (2.7) BS02 HEM 1.14.14.1 GO:0002933 ... P10632 14676196
    38981 1pq3:A (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38982 1pq3:A (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38983 1pq3:A (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189 PDBbind: -logKd/Ki=7.52, Ki=30nM
    38984 1pq3:B (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38985 1pq3:B (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38986 1pq3:B (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189
    38987 1pq3:C (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38988 1pq3:C (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38989 1pq3:C (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189
    38990 1pq3:D (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38991 1pq3:D (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38992 1pq3:D (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189
    38993 1pq3:E (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38994 1pq3:E (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38995 1pq3:E (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189
    38996 1pq3:F (2.7) BS01 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38997 1pq3:F (2.7) BS02 MN 3.5.3.1 GO:0004053 ... P78540 12859189
    38998 1pq3:F (2.7) BS03 S2C 3.5.3.1 GO:0004053 ... P78540 12859189
    38999 1pq4:A (1.9) BS01 ZN ? GO:0030001 ... P73085 14583199
    39000 1pq4:B (1.9) BS01 ZN ? GO:0030001 ... P73085 14583199

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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