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BioLiP
Download all results in tab-seperated text for 12 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    RNA
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 8fkz:L6
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0001824 ... P26373 37410842
    2 8fkz:L9
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P61313 37410842
    3 8fkz:LA
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P18621 37410842
    4 8fkz:LH
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0000027 ... P62750 37410842
    5 8fkz:LI
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P61254 37410842
    6 8fkz:LS
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0000463 ... P42766 37410842
    7 8fkz:LW
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P61927 37410842
    8 8fkz:LZ
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P62891 37410842
    9 8fkz:SA
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0002181 ... P36578 37410842
    10 8fkz:SE
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0000470 ... P62424 37410842
    11 8fkz:SM
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0000463 ... O00541 37410842
    12 8fkz:SR
    (3.04)
    BS01 >8fkz:L1 (identical to 8fl2:L1, 8fl3:L1, 8fl4:L1, 8fl6:L1, 8fl7:L1, 8fl9:L1, 8fla:L1, 8flb:L1, 8flc:L1, 8fld:L1, 8fle:L1, 8flf:L1)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
    cgaacgcacuugcggccccgggccucccggggcuacgccugucugagcgu
    cgcu
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>.............>>>..>...>>
    >....<<....>><<<<<<<<<...>>>>>>>>>................
    ....
    ? GO:0000079 ... Q9BZE4 37410842

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218