3mg4 L 3.11 BS01 MG D 1 S75 S78 S85 S88 3.4.25.1 0000502,0003674,0005515,0005634,0005737,0005829,0005839,0010499,0019774,0043161,0051603 P23724 20632995 2 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 3mg4 L 3.11 BS02 LXT K 1 D114 P115 D126 P127 3.4.25.1 0000502,0003674,0005515,0005634,0005737,0005829,0005839,0010499,0019774,0043161,0051603 -logKd/Ki=9.30, Ki=0.50nM P23724 20632995 213 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD 3mg4 L 3.11 BS03 MG L 1 T163 H166 V169 T192 H195 V198 3.4.25.1 0000502,0003674,0005515,0005634,0005737,0005829,0005839,0010499,0019774,0043161,0051603 P23724 20632995 195 QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD