1w7x H 1.8 BS01 CA H 1 E70 D72 E75 E80 E58 D60 E63 E68 3.4.21.21 0004252,0006508 P08709 16213138 1260 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP 1w7x H 1.8 BS02 413 H 1 H57 K60A T99 S170H P170I D189 S190 K192 S195 S214 W215 G216 Q217 G219 C220 H41 K45 T87 S164 P165 D182 S183 K185 S188 S207 W208 G209 Q210 G211 C212 3.4.21.21 0004252,0006508 Ki=0.004uM -logKd/Ki=8.40, Ki=0.004uM Ki=4nM P08709 16213138 1261 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP