3kcf E 2.8 BS01 JZO E 1 I211 A230 K232 Y249 L260 S280 Y282 H283 K337 L340 I41 A60 K62 Y79 L90 S110 Y112 H113 K167 L170 D333 K335 N338 D351 T375 D163 K165 N168 D181 T205 2.7.11.30 0004672,0004675,0005524,0006468,0007178,0016020 IC50=3690nM, Ki=35nM P36897 19914068 5 ISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG