3kcf D 2.8 BS01 JZO D 1 I211 K232 E245 Y249 L260 F262 S280 Y282 H283 L340 I41 K62 E75 Y79 L90 F92 S110 Y112 H113 L170 D333 K335 N338 D351 T375 D163 K165 N168 D181 T205 2.7.11.30 0004672,0004675,0005524,0006468,0007178,0016020 IC50=3690nM, Ki=35nM P36897 19914068 4 ISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG