2ozr C 2.3 BS01 ZN C 1 H201 H205 H211 H119 H123 H129 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17623656 4011 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD 2ozr C 2.3 BS02 ZN C 2 H151 D153 H166 H179 H69 D71 H84 H97 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17623656 4012 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD 2ozr C 2.3 BS03 CA C 1 D158 G159 S161 L163 D181 E184 D76 G77 S79 L81 D99 E102 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17623656 4013 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD 2ozr C 2.3 BS04 CA C 2 D141 N173 G175 D177 D59 N91 G93 D95 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17623656 4014 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD 2ozr C 2.3 BS05 CA C 3 D107 D182 E184 D25 D100 E102 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17623656 4015 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD 2ozr C 2.3 BS06 GG1 C 1 K119 F196 L197 H201 L218 F220 I222 Y223 Y225 T226 S229 F231 K37 F114 L115 H119 L136 F138 I140 Y141 Y143 T144 S147 F149 H201 E202 H205 H211 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 ic50=0.67nM -logKd/Ki=9.17, IC50=0.67nM IC50=0.670000nM P45452 17623656 2003 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGD