2iw9 C 2.0 BS01 4SP C 1 I10 G11 E12 G13 V18 A31 V64 F80 E81 F82 L83 H84 Q85 D86 T89 L134 I11 G12 E13 G14 V19 A32 V65 F81 E82 F83 L84 H85 Q86 D87 T90 L135 D127 K129 Q131 N132 D145 T158 T165 D128 K130 Q132 N133 D146 T159 T166 2.7.11.22 0000082,0000086,0000122,0000287,0000307,0000781,0000793,0000805,0000806,0001673,0004672,0004674,0004693,0005515,0005524,0005634,0005635,0005654,0005667,0005737,0005768,0005813,0005829,0005856,0006260,0006281,0006338,0006351,0006468,0006813,0007099,0007165,0007265,0007346,0008284,0010389,0010468,0015030,0016301,0016310,0018105,0019904,0030332,0031453,0031571,0032298,0035173,0043247,0043687,0045740,0045893,0046872,0051298,0051301,0051321,0071732,0090398,0097123,0097124,0097134,0097135,0097472,0106310,1905784 ic50=8.9nM IC50=6.0nM, Ki=6.0nM, Kd=1310nM P24941 16942020 1297 SMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKTFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL